Multivalent N-Acetylgalactosamine-Conjugated siRNA Localizes in Hepatocytes and Elicits Robust RNAi-Mediated Gene Silencing

JOURNAL ARTICLE published 10 December 2014 in Journal of the American Chemical Society

Authors: Jayaprakash K. Nair | Jennifer L. S. Willoughby | Amy Chan | Klaus Charisse | Md. Rowshon Alam | Qianfan Wang | Menno Hoekstra | Pachamuthu Kandasamy | Alexander V. Kel’in | Stuart Milstein | Nate Taneja | Jonathan O’Shea | Sarfraz Shaikh | Ligang Zhang | Ronald J. van der Sluis | Michael E. Jung | Akin Akinc | Renta Hutabarat | Satya Kuchimanchi | Kevin Fitzgerald | Tracy Zimmermann | Theo J. C. van Berkel | Martin A. Maier | Kallanthottathil G. Rajeev | Muthiah Manoharan