Targeting altered cancer methionine metabolism with recombinant methioninase (rMETase) overcomes partial gemcitabine-resistance and regresses a patient-derived orthotopic xenograft (PDOX) nude mouse model of pancreatic cancer

JOURNAL ARTICLE published 3 April 2018 in Cell Cycle

Authors: Kei Kawaguchi | Kentaro Miyake | Qinghong Han | Shukuan Li | Yuying Tan | Kentaro Igarashi | Thinzar M. Lwin | Takashi Higuchi | Tasuku Kiyuna | Masuyo Miyake | Hiromichi Oshiro | Michael Bouvet | Michiaki Unno | Robert M. Hoffman