Kinome-Wide RNA Interference Screen Reveals a Role for PDK1 in Acquired Resistance to CDK4/6 Inhibition in ER-Positive Breast Cancer

JOURNAL ARTICLE published 1 May 2017 in Cancer Research

Research funded by Cure Foundation (SAC100013) | Breast Cancer Research Foundation (8364) | NIH NCI (P50 CA98131 and P30 CA68485)

Authors: Valerie M. Jansen | Neil E. Bhola | Joshua A. Bauer | Luigi Formisano | Kyung-Min Lee | Katherine E. Hutchinson | Agnieszka K. Witkiewicz | Preston D. Moore | Mónica Valéria Estrada | Violeta Sánchez | Paula G. Ericsson | Melinda E. Sanders | Paula R. Pohlmann | Michael J. Pishvaian | David A. Riddle | Teresa C. Dugger | Wenyi Wei | Erik S. Knudsen | Carlos L. Arteaga