Oral Recombinant Methioninase, Combined With Oral Caffeine and Injected Cisplatinum, Overcome Cisplatinum-Resistance and Regresses Patient-derived Orthotopic Xenograft Model of Osteosarcoma

JOURNAL ARTICLE published September 2019 in Anticancer Research

Authors: TAKASHI HIGUCHI | HIROMICHI OSHIRO | KENTARO MIYAKE | NORIHIKO SUGISAWA | QINGHONG HAN | YUYING TAN | JUNHO PARK | ZHIYING ZHANG | SAHAR RAZMJOOEI | NORIO YAMAMOTO | KATSUHIRO HAYASHI | HIROAKI KIMURA | SHINJI MIWA | KENTARO IGARASHI | MICHAEL BOUVET | SANT P. CHAWLA | SHREE RAM SINGH | HIROYUKI TSUCHIYA | ROBERT M. HOFFMAN