Influenza evolution and H3N2 vaccine effectiveness, with application to the 2014/2015 season

JOURNAL ARTICLE published August 2016 in Protein Engineering Design and Selection

Authors: Xi Li | Michael W. Deem

Molecular modeling of HIV-1 reverse transcriptase drug-resistant mutant strains: implications for the mechanism of polymerase action

JOURNAL ARTICLE published 1 December 1997 in Protein Engineering Design and Selection

Authors: M. B. Kroeger Smith | C. J. Michejda | S. H. Hughes | P. L. Boyer | P. A. Janssen | K. Andries | R. W. Buckheit | R. H. Smith

The role of residues outside the active site: structural basis for function of C191 mutants of Escherichia coli aspartate aminotransferase

JOURNAL ARTICLE published February 2000 in Protein Engineering, Design and Selection

Authors: Constance J.Jeffery | Lisa M.Gloss | Gregory A.Petsko | Dagmar Ringe

Folding and stability of the active N-terminal domain of tissue inhibitor of metalloproteinases-1 and -2

JOURNAL ARTICLE published 1994 in "Protein Engineering, Design and Selection"

Authors: Richard A. Williamson | Helga Bartels | Gillian Murphy | Robert B. Freedman

Production, characterization and cytotoxic properties of a diphtheria toxin-ciliary neurotrophic factor fusion protein

JOURNAL ARTICLE published 1995 in "Protein Engineering, Design and Selection"

Authors: Alessandro Negro | Stephen D. Skaper

Molecular modelling and site-directed mutagenesis on a bovine anti-testosterone monoclonal antibody

JOURNAL ARTICLE published 1992 in "Protein Engineering, Design and Selection"

Authors: Terry Jackson | A.Brian Morris | C.R.Andrew Martin | F.V.David Lewis | G.Peter Sanders

Molecular modelling of UH-301 and 5-HT^la receptor interactions

JOURNAL ARTICLE published 1996 in "Protein Engineering, Design and Selection"

Authors: Ingebrigt Sylte | Øyvind Edvardsen | Svein G. Dahl

Engineered dimer interface mutants of triosephosphate isomerase: the role of inter-subunit interactions in enzyme function and stability

JOURNAL ARTICLE published 1 May 2011 in Protein Engineering Design and Selection

Authors: M. Banerjee | H. Balaram | N. V. Joshi | P. Balaram

Cold-adaptation mechanism of mutant enzymes of 3-isopropylmalate dehydrogenase from Thermus thermophilus

JOURNAL ARTICLE published June 2002 in Protein Engineering, Design and Selection

Authors: Toshiharu Suzuki | Masako Yasugi | Fumio Arisaka | Tairo Oshima | Akihiko Yamagishi

Thermostabilization by replacement of specific residues with lysine in a Bacillus alkaline cellulase: building a structural model and implications of newly formed double intrahelical salt bridges

JOURNAL ARTICLE published July 2001 in Protein Engineering, Design and Selection

Authors: Tadahiro Ozawa | Yoshihiro Hakamada | Yuji Hatada | Tohru Kobayashi | Tsuyoshi Shirai | Susumu Ito

Specificity grafting of human antibody frameworks selected from a phage display library: generation of a highly stable humanized anti-CD22 single-chain Fv fragment

JOURNAL ARTICLE published 1 October 2003 in Protein Engineering Design and Selection

Authors: J. Krauss | M. A.E. Arndt | A. C.R. Martin | H. Liu | S. M. Rybak

Stepwise transplantation of an active site loop between heat-labile enterotoxins LT-II and LT-I and characterization of the obtained hybrid toxins

JOURNAL ARTICLE published 1 November 1998 in Protein Engineering Design and Selection

Authors: I. K. Feil | A. A. Platas | F. van den Akker | R. Reddy | E. A. Merritt | D. R. Storm | W. G. Hol

Replacement of cysteine-107 of Saccharomyces cerevisiae iso-1-cytochrome c with threonine: improved stability of the mutant protein

JOURNAL ARTICLE published 1987 in "Protein Engineering, Design and Selection"

Authors: R.L. Cutler | G.J. Pielak | A. G. Mauk | M. Smith

On the classification of modular proteins

JOURNAL ARTICLE published 1996 in "Protein Engineering, Design and Selection"

Authors: Bernard Henrissat | Peer Bork

A single Fc binding domain–alkaline phosphatase gene fusion expresses a protein with both IgG binding ability and alkaline phosphatase enzymatic activity

JOURNAL ARTICLE published 1994 in "Protein Engineering, Design and Selection"

Authors: Chang-Lin Wang | May Huang | Carla A.R. Wesson | Dale C. Birdsell | William R. Trumble

Mutation of charged residues in the TR3 death domain does not perturb interaction with TRADD

JOURNAL ARTICLE published October 2002 in Protein Engineering, Design and Selection

Authors: Elisabeth Tunbridge | Colin Dingwall | Colin Edge | Madhavi Konduri | Douglas J. DeMarini | George P. Livi | Peter R. Maycox

Lessons from the Fersht laboratory could be vital for the future of the pharmaceutical industry

JOURNAL ARTICLE published 1 January 2011 in Protein Engineering Design and Selection

Authors: W. H. J. Ward

Exploring the unique pharmacology of a novel opioid receptor, ZFOR1, using molecular modeling and the `message–address' concept

JOURNAL ARTICLE published December 2001 in Protein Engineering, Design and Selection

Authors: Iain J. McFadyen | Thomas G. Metzger | M.Germana Paterlini | David M. Ferguson

A chimeric cysteine protease of Plasmodium berghei engineered to resemble the Plasmodium falciparum protease falcipain-2

JOURNAL ARTICLE published 1 January 2007 in Protein Engineering, Design and Selection

Authors: Ajay Singh | K. Jordan Walker | Puran S. Sijwali | Anthony L. Lau | Philip J. Rosenthal

A simple method for assessing the mutational effect on the protein-DNA interaction: application to amino acid substitutions

JOURNAL ARTICLE published 1994 in "Protein Engineering, Design and Selection"

Authors: Yifei Wang | Akinori Sarai