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Intravital Imaging Reveals How BRAF Inhibition Generates Drug-Tolerant Microenvironments with High Integrin β1/FAK Signaling

JOURNAL ARTICLE published April 2015 in Cancer Cell

Authors: Eishu Hirata | Maria Romina Girotti | Amaya Viros | Steven Hooper | Bradley Spencer-Dene | Michiyuki Matsuda | James Larkin | Richard Marais | Erik Sahai

Role of Nucleosomal Occupancy in the Epigenetic Silencing of the MLH1 CpG Island

JOURNAL ARTICLE published November 2007 in Cancer Cell

Authors: Joy C. Lin | Shinwu Jeong | Gangning Liang | Daiya Takai | Merhnaz Fatemi | Yvonne C. Tsai | Gerda Egger | Einav Nili Gal-Yam | Peter A. Jones

Myeloproliferative stem cell disorders by deregulated Rap1 activation in SPA-1-deficient mice

JOURNAL ARTICLE published July 2003 in Cancer Cell

Authors: Daisuke Ishida | Kohei Kometani | Hailin Yang | Kiyokazu Kakugawa | Kyoko Masuda | Kazuhiro Iwai | Misao Suzuki | Shigeyoshi Itohara | Tatsutoshi Nakahata | Hiroshi Hiai | Hiroshi Kawamoto | Masakazu Hattori | Nagahiro Minato

The Role of SPINK1 in ETS Rearrangement-Negative Prostate Cancers

JOURNAL ARTICLE published June 2008 in Cancer Cell

Authors: Scott A. Tomlins | Daniel R. Rhodes | Jianjun Yu | Sooryanarayana Varambally | Rohit Mehra | Sven Perner | Francesca Demichelis | Beth E. Helgeson | Bharathi Laxman | David S. Morris | Qi Cao | Xuhong Cao | Ove Andrén | Katja Fall | Laura Johnson | John T. Wei | Rajal B. Shah | Hikmat Al-Ahmadie | James A. Eastham | Scott E. Eggener | Samson W. Fine | Kristina Hotakainen | Ulf-Håkan Stenman | Alex Tsodikov | William L. Gerald | Hans Lilja | Victor E. Reuter | Phillip W. Kantoff | Peter T. Scardino | Mark A. Rubin | Anders S. Bjartell | Arul M. Chinnaiyan

CREPT Accelerates Tumorigenesis by Regulating the Transcription of Cell-Cycle-Related Genes

JOURNAL ARTICLE published January 2012 in Cancer Cell

Authors: Dongdong Lu | Yinyuan Wu | Yinyin Wang | Fangli Ren | Dianjun Wang | Fuqin Su | Yanquan Zhang | Xi Yang | Guihua Jin | Xinbao Hao | Dacheng He | Yonggong Zhai | David M. Irwin | Jim Hu | Joseph J.Y. Sung | Jun Yu | Baoqing Jia | Zhijie Chang

A signaling pathway leading to metastasis is controlled by N-cadherin and the FGF receptor

JOURNAL ARTICLE published October 2002 in Cancer Cell

Authors: Kimita Suyama | Irina Shapiro | Mitchell Guttman | Rachel B. Hazan

Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling

JOURNAL ARTICLE published March 2002 in Cancer Cell

Authors: Eng-Juh Yeoh | Mary E Ross | Sheila A Shurtleff | W.Kent Williams | Divyen Patel | Rami Mahfouz | Fred G Behm | Susana C Raimondi | Mary V Relling | Anami Patel | Cheng Cheng | Dario Campana | Dawn Wilkins | Xiaodong Zhou | Jinyan Li | Huiqing Liu | Ching-Hon Pui | William E Evans | Clayton Naeve | Limsoon Wong | James R Downing

Orai1 and STIM1 Are Critical for Breast Tumor Cell Migration and Metastasis

JOURNAL ARTICLE published February 2009 in Cancer Cell

Authors: Shengyu Yang | J. Jillian Zhang | Xin-Yun Huang

β4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium

JOURNAL ARTICLE published September 2002 in Cancer Cell

Authors: Valerie M Weaver | Sophie Lelièvre | Johnathon N Lakins | Micah A Chrenek | Jonathan C.R Jones | Filippo Giancotti | Zena Werb | Mina J Bissell

p63 and p73 are not required for the development and p53-dependent apoptosis of T cells

JOURNAL ARTICLE published July 2004 in Cancer Cell

Authors: Makoto Senoo | John P Manis | Frederick W Alt | Frank McKeon

A Case of Mistaken Identity? Nonductal Origins of Pancreatic “Ductal” Cancers

JOURNAL ARTICLE published March 2007 in Cancer Cell

Authors: L. Charles Murtaugh | Steven D. Leach

RNA interference: the new somatic cell genetics?

JOURNAL ARTICLE published July 2002 in Cancer Cell

Authors: Patrick J Paddison | Gregory J Hannon

Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors

JOURNAL ARTICLE published May 2004 in Cancer Cell

Authors: Benjamin J Moeller | Yiting Cao | Chuan Y Li | Mark W Dewhirst

The DLEU2/miR-15a/16-1 Cluster Controls B Cell Proliferation and Its Deletion Leads to Chronic Lymphocytic Leukemia

JOURNAL ARTICLE published January 2010 in Cancer Cell

Authors: Ulf Klein | Marie Lia | Marta Crespo | Rachael Siegel | Qiong Shen | Tongwei Mo | Alberto Ambesi-Impiombato | Andrea Califano | Anna Migliazza | Govind Bhagat | Riccardo Dalla-Favera

Regulators of Mitotic Arrest and Ceramide Metabolism Are Determinants of Sensitivity to Paclitaxel and Other Chemotherapeutic Drugs

JOURNAL ARTICLE published June 2007 in Cancer Cell

Authors: Charles Swanton | Michela Marani | Olivier Pardo | Patricia H. Warne | Gavin Kelly | Erik Sahai | Frédéric Elustondo | Jenny Chang | Jillian Temple | Ahmed A. Ahmed | James D. Brenton | Julian Downward | Barbara Nicke

Efficacy of TG101348, a Selective JAK2 Inhibitor, in Treatment of a Murine Model of JAK2V617F-Induced Polycythemia Vera

JOURNAL ARTICLE published April 2008 in Cancer Cell

Authors: Gerlinde Wernig | Michael G. Kharas | Rachel Okabe | Sandra A. Moore | Dena S. Leeman | Dana E. Cullen | Maricel Gozo | Elizabeth P. McDowell | Ross L. Levine | John Doukas | Chi Ching Mak | Glenn Noronha | Michael Martin | Yon D. Ko | Benjamin H. Lee | Richard M. Soll | Ayalew Tefferi | John D. Hood | D. Gary Gilliland

Cell tension, matrix mechanics, and cancer development

JOURNAL ARTICLE published September 2005 in Cancer Cell

Authors: Sui Huang | Donald E. Ingber

Inhibition of HER-kinase activation prevents ERK-mediated degradation of PPARγ

JOURNAL ARTICLE published June 2004 in Cancer Cell

Authors: Michael Hedvat | Anjali Jain | Dennis A Carson | Lorenzo M Leoni | Ganghua Huang | Stuart Holden | Desheng Lu | Maripat Corr | William Fox | David B Agus

Preexistence and Clonal Selection of MET Amplification in EGFR Mutant NSCLC

JOURNAL ARTICLE published January 2010 in Cancer Cell

Authors: Alexa B. Turke | Kreshnik Zejnullahu | Yi-Long Wu | Youngchul Song | Dora Dias-Santagata | Eugene Lifshits | Luca Toschi | Andrew Rogers | Tony Mok | Lecia Sequist | Neal I. Lindeman | Carly Murphy | Sara Akhavanfard | Beow Y. Yeap | Yun Xiao | Marzia Capelletti | A. John Iafrate | Charles Lee | James G. Christensen | Jeffrey A. Engelman | Pasi A. Jänne

Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein

JOURNAL ARTICLE published April 2002 in Cancer Cell

Authors: Keiichi Kondo | Jeff Klco | Eijiro Nakamura | Mirna Lechpammer | William G Kaelin