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Capitalizing on Cancer Replication Stress by Preventing PAR Chain Turnover: A New Type of Synthetic Lethality

JOURNAL ARTICLE published April 2019 in Cancer Cell

Authors: Niamh McDermott | Erika S. Buechelmaier | Simon N. Powell

Re: a Word of Caution on New and Revolutionary Diagnostic Tests

JOURNAL ARTICLE published February 2016 in Cancer Cell

Authors: Myron G. Best | Nik Sol | Bakhos A. Tannous | Pieter Wesseling | Thomas Wurdinger

It's a Free for All—Insulin-Positive Cells Join the Group of Potential Progenitors for Pancreatic Ductal Adenocarcinoma

JOURNAL ARTICLE published November 2009 in Cancer Cell

Authors: John P. Morris | Matthias Hebrok

More Rules, Still Exceptions: Understanding Immunomodulatory Antibody Activity In Vivo

JOURNAL ARTICLE published April 2018 in Cancer Cell

Authors: Andrea Ipsen-Escobedo | Falk Nimmerjahn

Proteasome Inhibitors Evoke Latent Tumor Suppression Programs in Pro-B MLL Leukemias through MLL-AF4

JOURNAL ARTICLE published April 2014 in Cancer Cell

Authors: Han Liu | Todd D. Westergard | Amanda Cashen | David R. Piwnica-Worms | Lori Kunkle | Ravi Vij | Can G. Pham | John DiPersio | Emily H. Cheng | James J. Hsieh

The Role of Cdk5 in Neuroendocrine Thyroid Cancer

JOURNAL ARTICLE published October 2013 in Cancer Cell

Authors: Karine Pozo | Emely Castro-Rivera | Chunfeng Tan | Florian Plattner | Gert Schwach | Veronika Siegl | Douglas Meyer | Ailan Guo | Justin Gundara | Gabriel Mettlach | Edmond Richer | Jonathan A. Guevara | Li Ning | Anjali Gupta | Guiyang Hao | Li-Huei Tsai | Xiankai Sun | Pietro Antich | Stanley Sidhu | Bruce G. Robinson | Herbert Chen | Fiemu E. Nwariaku | Roswitha Pfragner | James A. Richardson | James A. Bibb

The Immune Revolution: A Case for Priming, Not Checkpoint

JOURNAL ARTICLE published April 2018 in Cancer Cell

Research funded by NIH (R01 CA169123,P01 CA210944,P30 CA016520)

Authors: Robert H. Vonderheide

Dysregulated IL-18 Is a Key Driver of Immunosuppression and a Possible Therapeutic Target in the Multiple Myeloma Microenvironment

JOURNAL ARTICLE published April 2018 in Cancer Cell

Research funded by Cure Cancer Australia and Cancer Australia (1139523,1122183) | National Health and Medical Research Council (1107417,1124690,1132519) | Austrian Science Fund (J-3635) | EMBO (ALT945-2015) | DFG (EXC 1023) | NCI (CA190045,CA186781) | Institut National Du Cancer (PLBIO 16)

Authors: Kyohei Nakamura | Sahar Kassem | Alice Cleynen | Marie-Lorraine Chrétien | Camille Guillerey | Eva Maria Putz | Tobias Bald | Irmgard Förster | Slavica Vuckovic | Geoffrey R. Hill | Seth L. Masters | Marta Chesi | P. Leif Bergsagel | Hervé Avet-Loiseau | Ludovic Martinet | Mark J. Smyth

Sequential Therapy with PARP and WEE1 Inhibitors Minimizes Toxicity while Maintaining Efficacy

JOURNAL ARTICLE published June 2019 in Cancer Cell

Research funded by NIH (CA217842,CA217685,CA098258,CA210950,HG008100) | Komen Foundation (SAC110052) | Breast Cancer Research Foundation (BCRF-17-108) | CPRIT (RP170640,RR160021,FG-2018-10723) | CCSG (CA016672) | Susan G. Komen grant (PDF17483544)

Authors: Yong Fang | Daniel J. McGrail | Chaoyang Sun | Marilyne Labrie | Xiaohua Chen | Dong Zhang | Zhenlin Ju | Christopher P. Vellano | Yiling Lu | Yongsheng Li | Kang Jin Jeong | Zhiyong Ding | Jiyong Liang | Steven W. Wang | Hui Dai | Sanghoon Lee | Nidhi Sahni | Imelda Mercado-Uribe | Tae-beom Kim | Ken Chen | Shiaw-Yih Lin | Guang Peng | Shannon N. Westin | Jinsong Liu | Mark J. O'Connor | Timothy A. Yap | Gordon B. Mills

MEK inhibition overcomes chemoimmunotherapy resistance by inducing CXCL10 in cancer cells

JOURNAL ARTICLE published February 2022 in Cancer Cell

Authors: Emeric Limagne | Lisa Nuttin | Marion Thibaudin | Elise Jacquin | Romain Aucagne | Marjorie Bon | Solène Revy | Robby Barnestein | Elise Ballot | Caroline Truntzer | Valentin Derangère | Jean-David Fumet | Charlène Latour | Cédric Rébé | Pierre-Simon Bellaye | Coureche-Guillaume Kaderbhaï | Aodrenn Spill | Bertrand Collin | Mary B. Callanan | Aurélie Lagrange | Laure Favier | Bruno Coudert | Laurent Arnould | Sylvain Ladoire | Bertrand Routy | Philippe Joubert | François Ghiringhelli

The Architecture and Evolution of Cancer Neochromosomes

JOURNAL ARTICLE published November 2014 in Cancer Cell

Authors: Dale W. Garsed | Owen J. Marshall | Vincent D.A. Corbin | Arthur Hsu | Leon Di Stefano | Jan Schröder | Jason Li | Zhi-Ping Feng | Bo W. Kim | Mark Kowarsky | Ben Lansdell | Ross Brookwell | Ola Myklebost | Leonardo Meza-Zepeda | Andrew J. Holloway | Florence Pedeutour | K.H. Andy Choo | Michael A. Damore | Andrew J. Deans | Anthony T. Papenfuss | David M. Thomas

Data Triumph at C

JOURNAL ARTICLE published April 2017 in Cancer Cell

Research funded by Marcus Foundation (NCT02516670)

Authors: Mark Levine | Pierre-Christian Violet

Cancer and Apoptosis: Who Is Built to Last?

JOURNAL ARTICLE published January 2017 in Cancer Cell

Authors: Douglas R. Green

Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex

JOURNAL ARTICLE published April 2004 in Cancer Cell

Authors: Matthew C Franklin | Kendall D Carey | Felix F Vajdos | Daniel J Leahy | Abraham M de Vos | Mark X Sliwkowski

Head of the Class: OLIG2 and Glioblastoma Phenotype

JOURNAL ARTICLE published May 2016 in Cancer Cell

Research funded by NIH (R01NS096238)

Authors: Nalin Leelatian | Rebecca A. Ihrie

Recurrent DGCR8, DROSHA, and SIX Homeodomain Mutations in Favorable Histology Wilms Tumors

JOURNAL ARTICLE published March 2015 in Cancer Cell

Authors: Amy L. Walz | Ariadne Ooms | Samantha Gadd | Daniela S. Gerhard | Malcolm A. Smith | Jaime M. Guidry Auvil | Daoud Meerzaman | Qing-Rong Chen | Chih Hao Hsu | Chunhua Yan | Cu Nguyen | Ying Hu | Reanne Bowlby | Denise Brooks | Yussanne Ma | Andrew J. Mungall | Richard A. Moore | Jacqueline Schein | Marco A. Marra | Vicki Huff | Jeffrey S. Dome | Yueh-Yun Chi | Charles G. Mullighan | Jing Ma | David A. Wheeler | Oliver A. Hampton | Nadereh Jafari | Nicole Ross | Julie M. Gastier-Foster | Elizabeth J. Perlman

Determinants of Oncogenic Transformation in Acute Promyelocytic Leukemia: The Hetero-Union Makes the Force

JOURNAL ARTICLE published July 2007 in Cancer Cell

Authors: Saverio Minucci | Pier Giuseppe Pelicci

Pancreatic Cancer: Planning Ahead for Metastatic Spread

JOURNAL ARTICLE published June 2016 in Cancer Cell

Authors: Ingunn M. Stromnes | Philip D. Greenberg

Human C-Reactive Protein Binds Activating Fcγ Receptors and Protects Myeloma Tumor Cells from Apoptosis

JOURNAL ARTICLE published September 2007 in Cancer Cell

Authors: Jing Yang | Michele Wezeman | Xiang Zhang | Pei Lin | Michael Wang | Jianfei Qian | Bo Wan | Larry W. Kwak | Long Yu | Qing Yi

Olig2-Dependent Reciprocal Shift in PDGF and EGF Receptor Signaling Regulates Tumor Phenotype and Mitotic Growth in Malignant Glioma

JOURNAL ARTICLE published May 2016 in Cancer Cell

Research funded by NIH (R01 NS078092,R01 NS075243)

Authors: Fanghui Lu | Ying Chen | Chuntao Zhao | Haibo Wang | Danyang He | Lingli Xu | Jincheng Wang | Xuelian He | Yaqi Deng | Ellen E. Lu | Xue Liu | Ravinder Verma | Hong Bu | Rachid Drissi | Maryam Fouladi | Anat O. Stemmer-Rachamimov | Dennis Burns | Mei Xin | Joshua B. Rubin | El Mustapha Bahassi | Peter Canoll | Eric C. Holland | Q. Richard Lu