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Replacing what’s lost: a new era of stem cell therapy for Parkinson’s disease

JOURNAL ARTICLE published December 2020 in Translational Neurodegeneration

Research funded by National Medical Research Council (NMRC/OFYIRG/2016/11)

Authors: Yong Fan | Shi-Yan Ng

How to spot ocular abnormalities in progressive supranuclear palsy? A practical review

JOURNAL ARTICLE published December 2019 in Translational Neurodegeneration

Research funded by Chulalongkorn University (the Chulalongkorn Academic Advancement Fund into Its 2nd Century Project of Chulalongkorn University (2300042200),Center of Excellence grant (GCE 6100930004-1))

Authors: Onanong Phokaewvarangkul | Roongroj Bhidayasiri

Considerations for biomarker strategies in clinical trials investigating tau-targeting therapeutics for Alzheimer’s disease

JOURNAL ARTICLE published 21 May 2024 in Translational Neurodegeneration

Authors: Lewis K. Penny | Richard Lofthouse | Mohammad Arastoo | Andy Porter | Soumya Palliyil | Charles R. Harrington | Claude M. Wischik

A longitudinal assessment of retinal function and structure in the APP/PS1 transgenic mouse model of Alzheimer’s disease

JOURNAL ARTICLE published December 2019 in Translational Neurodegeneration

Research funded by National Health and Medical Research Council (GNT1105930,GNT1101258) | Mason Foundation (MAS2017F019)

Authors: Dana Georgevsky | Stephanie Retsas | Newsha Raoufi | Olga Shimoni | S. Mojtaba Golzan

Neuronal and synaptic adaptations underlying the benefits of deep brain stimulation for Parkinson's disease

JOURNAL ARTICLE published 30 November 2023 in Translational Neurodegeneration

Research funded by STI2030-Major Projects (2022ZD0208605) | National Natural Science Foundation of China (32071023,82271274,82171242) | Shanghai Association for Science and Technology (22XD1420700) | Shanghai Municipal Health Commission (2022XD046) | Shanghai Municipal Education Commission (SHSMU-ZDCX20211901)

Authors: Wenying Xu | Jie Wang | Xin-Ni Li | Jingxue Liang | Lu Song | Yi Wu | Zhenguo Liu | Bomin Sun | Wei-Guang Li

Early life adversity as a risk factor for cognitive impairment and Alzheimer’s disease

JOURNAL ARTICLE published 12 May 2023 in Translational Neurodegeneration

Research funded by National Institute on Aging (RF1AG058603)

Authors: Zhihai Huang | J. Dedrick Jordan | Quanguang Zhang

Neuroinflammation in neurodegenerative disorders: the roles of microglia and astrocytes

JOURNAL ARTICLE published December 2020 in Translational Neurodegeneration

Research funded by Ministry of Science, ICT and Future Planning (2018R1A2A2A15023219) | Ministry of Health and Welfare (grant number: HI20C0253) | Medical Research Centre (2017R1A5A2015395)

Authors: Hyuk Sung Kwon | Seong-Ho Koh

RNAi mechanisms in Huntington’s disease therapy: siRNA versus shRNA

JOURNAL ARTICLE published December 2017 in Translational Neurodegeneration

Authors: Sebastian Aguiar | Bram van der Gaag | Francesco Albert Bosco Cortese

Clinicians’ prescription preferences for treating patients with Alzheimer’s disease in Shanghai

JOURNAL ARTICLE published December 2016 in Translational Neurodegeneration

Research funded by National Key Clinical Disciplines to the Shanghai Mental Health Center (Office of Medical Affairs, Ministry of Health, 2011-873; OMA-MH, 2011-873) | the Shanghai Clinical Center for Mental Disorders (2014) | Shanghai Science and Technology Committee (15411961400)

Authors: Chun-Xia Ban | Shi-Fu Xiao | Xiang Lin | Tao Wang | Qi Qiu | Min-Jie Zhu | Xia Li

Clinical and genetic characterization of a large cohort of patients with Wilson’s disease in China

JOURNAL ARTICLE published December 2022 in Translational Neurodegeneration

Research funded by National Natural Science Foundation of China (81903895,81973825,82104783) | Natural Science Foundation of Anhui Province (1908085QC90) | Anhui University Collaborative Innovation Project (GXXT-2020-025)

Authors: Shijie Zhang | Wenming Yang | Xiang Li | Pei Pei | Ting Dong | Yue Yang | Jing Zhang

Mini-review on initiatives to interfere with the propagation and clearance of alpha-synuclein in Parkinson’s disease

JOURNAL ARTICLE published December 2017 in Translational Neurodegeneration

Authors: Daniel Kam Yin Chan | Ying Hua Xu | Luke Kar Man Chan | Nady Braidy | George D. Mellick

Role of early life exposure and environment on neurodegeneration: implications on brain disorders

JOURNAL ARTICLE published December 2014 in Translational Neurodegeneration

Authors: Shweta Modgil | Debomoy K Lahiri | Vijay L Sharma | Akshay Anand

CRISPR/dCas9-Dnmt3a-mediated targeted DNA methylation of APP rescues brain pathology in a mouse model of Alzheimer’s disease

JOURNAL ARTICLE published 15 September 2022 in Translational Neurodegeneration

Research funded by Ministry of Health and Welfare (2021M3E5E5096464) | Ministry of Education (NRF-2022R1A6A1A03053343)

Authors: Hanseul Park | Jaein Shin | Yunkyung Kim | Takashi Saito | Takaomi C. Saido | Jongpil Kim

Modulation of tau phosphorylation by environmental copper

JOURNAL ARTICLE published December 2014 in Translational Neurodegeneration

Authors: Kellen Voss | Christopher Harris | Martina Ralle | Megan Duffy | Charles Murchison | Joseph F Quinn

Amyloid, tau, pathogen infection and antimicrobial protection in Alzheimer’s disease –conformist, nonconformist, and realistic prospects for AD pathogenesis

JOURNAL ARTICLE published December 2018 in Translational Neurodegeneration

Research funded by National Institutes of Health (AG059217,AG061875,AG062257,AG057509,AG054111,AG020670,AG057981) | BrightFocus Foundation (A2016346F) | Alzheimer Association (AARG-17-500335) | Florida Department of Health (8AZ07)

Authors: Hongmei Li | Chia-Chen Liu | Hui Zheng | Timothy Y. Huang

Why do ‘OFF’ periods still occur during continuous drug delivery in Parkinson’s disease?

JOURNAL ARTICLE published 13 October 2022 in Translational Neurodegeneration

Authors: Silvia Rota | Daniele Urso | Daniel J. van Wamelen | Valentina Leta | Iro Boura | Per Odin | Alberto J. Espay | Peter Jenner | K. Ray Chaudhuri

The interplay of aging, genetics and environmental factors in the pathogenesis of Parkinson’s disease

JOURNAL ARTICLE published December 2019 in Translational Neurodegeneration

Research funded by Tai Hung Fai Charitable Foundation - Edwin S H Leong Research Programme for Parkinson’s Disease (N/A) | The Henry G. Leong Endowed Professorship in Neurology (N/A) | The Donation Fund for Neurology Research (N/A) | Health and Medical Research Fund (N/A)

Authors: Shirley Yin-Yu Pang | Philip Wing-Lok Ho | Hui-Fang Liu | Chi-Ting Leung | Lingfei Li | Eunice Eun Seo Chang | David Boyer Ramsden | Shu-Leong Ho

α-Synuclein conformers reveal link to clinical heterogeneity of α-synucleinopathies

JOURNAL ARTICLE published 14 March 2023 in Translational Neurodegeneration

Authors: Matthias Schmitz | Niccolò Candelise | Sezgi Canaslan | Hermann C. Altmeppen | Jakob Matschke | Markus Glatzel | Neelam Younas | Saima Zafar | Peter Hermann | Inga Zerr

Neurofilament light chain is increased in the parahippocampal cortex and associates with pathological hallmarks in Parkinson’s disease dementia

JOURNAL ARTICLE published 20 January 2023 in Translational Neurodegeneration

Research funded by Michael J. Fox Foundation for Parkinson's Research (17253) | Stichting ParkinsonFonds (1881)

Authors: Irene Frigerio | Max A. Laansma | Chen-Pei Lin | Emma J. M. Hermans | Maud M. A. Bouwman | John G. J. M. Bol | Yvon Galis-de Graaf | Dagmar H. Hepp | Annemieke J. M. Rozemuller | Frederik Barkhof | Wilma D. J. van de Berg | Laura E. Jonkman

Ecto-GPR37: a potential biomarker for Parkinson’s disease

JOURNAL ARTICLE published 26 February 2021 in Translational Neurodegeneration

Research funded by Ministerio de Ciencia, Innovación y Universidades (SAF2017-87349-R,MDM-2017-0729) | Instituto de Salud Carlos III (PIE14/00034,PI19/00144)

Authors: Xavier Morató | Paula Garcia-Esparcia | Josep Argerich | Franc Llorens | Inga Zerr | Wojciech Paslawski | Eva Borràs | Eduard Sabidó | Ulla E. Petäjä-Repo | Víctor Fernández-Dueñas | Isidro Ferrer | Per Svenningsson | Francisco Ciruela