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Showing results for ISSN matching 0022-2623

Tackling Antimicrobial Resistance with Small Molecules Targeting LsrK: Challenges and Opportunities

JOURNAL ARTICLE published 24 December 2020 in Journal of Medicinal Chemistry

Authors: Pasquale Linciano | Valeria Cavalloro | Emanuela Martino | Johannes Kirchmair | Roberta Listro | Daniela Rossi | Simona Collina

https://doi.org/10.1021/acs.jmedchem.0c01282 Actions

Phosphate Chemical Probes Designed for Location Specific Inhibition of Intracellular Carbonic Anhydrases

JOURNAL ARTICLE published 24 September 2015 in Journal of Medicinal Chemistry

Research funded by Australian Research Council (DP110100071,FT10100185)

Authors: Gregory M. Rankin | Daniela Vullo | Claudiu T. Supuran | Sally-Ann Poulsen

https://doi.org/10.1021/acs.jmedchem.5b01228 Actions

Exploration of the Amine Terminus in a Novel Series of 1,2,4-Triazolo-3-yl-azabicyclo[3.1.0]hexanes as Selective Dopamine D3 Receptor Antagonists

JOURNAL ARTICLE published 14 October 2010 in Journal of Medicinal Chemistry

Authors: Fabrizio Micheli | Luca Arista | Barbara Bertani | Simone Braggio | Anna Maria Capelli | Susanna Cremonesi | Romano Di-Fabio | Giacomo Gelardi | Gabriella Gentile | Carla Marchioro | Alessandra Pasquarello | Stefano Provera | Giovanna Tedesco | Luca Tarsi | Silvia Terreni | Angela Worby | Christian Heidbreder

https://doi.org/10.1021/jm100832d Actions

Structure−Activity Studies on a Series of a 2-Aminopyrimidine-Containing Histamine H4 Receptor Ligands

JOURNAL ARTICLE published 23 October 2008 in Journal of Medicinal Chemistry

Authors: Robert J. Altenbach | Ronald M. Adair | Brian M. Bettencourt | Lawrence A. Black | Shannon R. Fix-Stenzel | Sujatha M. Gopalakrishnan | Gin C. Hsieh | Huaqing Liu | Kennan C. Marsh | Michael J. McPherson | Ivan Milicic | Thomas R. Miller | Timothy A. Vortherms | Usha Warrior | Jill M. Wetter | Neil Wishart | David G. Witte | Prisca Honore | Timothy A. Esbenshade | Arthur A. Hancock | Jorge D. Brioni | Marlon D. Cowart

https://doi.org/10.1021/jm8005959 Actions

Quick Assembly of 1,4-Diphenyltriazoles as Probes Targeting β-Amyloid Aggregates in Alzheimer's Disease

JOURNAL ARTICLE published 1 July 2007 in Journal of Medicinal Chemistry

Authors: Wenchao Qu | Mei-Ping Kung | Catherine Hou | Shunichi Oya | Hank F. Kung

https://doi.org/10.1021/jm070467l Actions

Synthesis and Optimization of a New Family of Type 3 17β-Hydroxysteroid Dehydrogenase Inhibitors by Parallel Liquid-Phase Chemistry

JOURNAL ARTICLE published 1 January 2002 in Journal of Medicinal Chemistry

Authors: René Maltais | Van Luu-The | Donald Poirier

https://doi.org/10.1021/jm010286y Actions

Corrections to Rational Modification of a Candidate Cancer Drug for Use against Chagas Disease

JOURNAL ARTICLE published 23 July 2009 in Journal of Medicinal Chemistry

Authors: James M. Kraus | Christophe L. M. J. Verlinde | Mandana Karimi | Galina I. Lepesheva | Michael H. Gelb | Frederick S. Buckner

https://doi.org/10.1021/jm900650s Actions

New Anticancer Agents Mimicking Protein Recognition Motifs

JOURNAL ARTICLE published 12 September 2013 in Journal of Medicinal Chemistry

Authors: Marco Persico | Anna Ramunno | Vita Maglio | Silvia Franceschelli | Chiara Esposito | Alfonso Carotenuto | Diego Brancaccio | Valeria De Pasquale | Luigi Michele Pavone | Michela Varra | Nausicaa Orteca | Ettore Novellino | Caterina Fattorusso

https://doi.org/10.1021/jm400947b Actions

Synthesis of two metabolites of (+)-propoxyphene

JOURNAL ARTICLE published August 1977 in Journal of Medicinal Chemistry

Authors: William W. Turner | Richard N. Booher | Stephen E. Smits | Albert Pohland

https://doi.org/10.1021/jm00218a015 Actions

Miliusanes, A Class of Cytotoxic Agents from Miliusa sinensis

JOURNAL ARTICLE published 1 January 2006 in Journal of Medicinal Chemistry

Authors: Hong-Jie Zhang | Cuiying Ma | Nguyen Van Hung | Nguyen Manh Cuong | Ghee Teng Tan | Bernard D. Santarsiero | Andrew D. Mesecar | D. Doel Soejarto | John M. Pezzuto | Harry H. S. Fong

https://doi.org/10.1021/jm0509492 Actions

Acridine-Based Agents with Topoisomerase II Activity Inhibit Pancreatic Cancer Cell Proliferation and Induce Apoptosis

JOURNAL ARTICLE published 1 January 2008 in Journal of Medicinal Chemistry

Authors: John R. Goodell | Andrei V. Ougolkov | Hiroshi Hiasa | Harneet Kaur | Rory Remmel | Daniel D. Billadeau | David M. Ferguson

https://doi.org/10.1021/jm701228e Actions

2,6,8-Trisubstituted 1-Deazapurines as Adenosine Receptor Antagonists

JOURNAL ARTICLE published 1 February 2007 in Journal of Medicinal Chemistry

Authors: Lisa C. W. Chang | Jacobien K. von Frijtag Drabbe Künzel | Thea Mulder-Krieger | Joost Westerhout | Thomas Spangenberg | Johannes Brussee | Adriaan P. IJzerman

https://doi.org/10.1021/jm0607956 Actions

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JOURNAL ARTICLE published 1 July 1960 in Journal of Medicinal Chemistry

https://doi.org/10.1021/jm50011a902 Actions

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JOURNAL ARTICLE published 1 February 1961 in Journal of Medicinal Chemistry

https://doi.org/10.1021/jm50014a908 Actions

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JOURNAL ARTICLE published 1 April 1961 in Journal of Medicinal Chemistry

https://doi.org/10.1021/jm50015a903 Actions

Discovery of Orally Bioavailable 1,3,4-Trisubstituted 2-Oxopiperazine-Based Melanocortin-4 Receptor Agonists as Potential Antiobesity Agents

JOURNAL ARTICLE published 9 October 2008 in Journal of Medicinal Chemistry

Authors: Xinrong Tian | Adrian G. Switzer | Steve A. Derose | Rajesh K. Mishra | Mark G. Solinsky | Rashid N. Mumin | Frank H. Ebetino | Lalith R. Jayasinghe | Mark E. Webster | Anny-Odile Colson | Doreen Crossdoersen | Beth B. Pinney | Julie A. Farmer | Martin E. Dowty | Cindy M. Obringer | Charles A. Cruze | Melissa L. Burklow | Paula M. Suchanek | Lily Dong | Mary Kay Dirr | Russell J. Sheldon | John A. Wos

https://doi.org/10.1021/jm800525p Actions

Novel Bis(1H-indol-2-yl)methanones as Potent Inhibitors of FLT3 and Platelet-Derived Growth Factor Receptor Tyrosine Kinase

JOURNAL ARTICLE published 1 June 2006 in Journal of Medicinal Chemistry

Authors: Siavosh Mahboobi | Andrea Uecker | Andreas Sellmer | Christophe Cénac | Heymo Höcher | Herwig Pongratz | Emerich Eichhorn | Harald Hufsky | Antje Trümpler | Marit Sicker | Florian Heidel | Thomas Fischer | Carol Stocking | Sigurd Elz | Frank-D. Böhmer | Stefan Dove

https://doi.org/10.1021/jm058033i Actions

(+)-cis-N-(para-, meta-, and ortho-substituted benzyl)-N-normetazocines: Synthesis and binding affinity at the [3H]-(+)-pentazocine-labeled (.sigma.1) site and quantitative structure-affinity relationship studies

JOURNAL ARTICLE published February 1995 in Journal of Medicinal Chemistry

Authors: S. Wayne Mascarella | Xu Bai | Wanda Williams | Bethel Sine | Wayne D. Bowen | F. Ivy Carroll

https://doi.org/10.1021/jm00003a019 Actions

Iodinated 2-Aminotetralins and 3-Amino-1-benzopyrans: Ligands for Dopamine D2 and D3 Receptors

JOURNAL ARTICLE published November 1994 in Journal of Medicinal Chemistry

Authors: Sumalee Chumpradit | Mei-Ping Kung | Janet Vessotskie | Catherine Foulon | Mu Mu | Hank F. Kung

https://doi.org/10.1021/jm00050a021 Actions

Novel Ligands Rationally Designed for Characterizing I2−Imidazoline Binding Sites Nature and Functions

JOURNAL ARTICLE published 1 August 2008 in Journal of Medicinal Chemistry

Authors: Francesco Gentili | Claudia Cardinaletti | Cristian Vesprini | Francesca Ghelfi | Aniket Farande | Mario Giannella | Alessandro Piergentili | Wilma Quaglia | Laura Mattioli | Marina Perfumi | Alan Hudson | Maria Pigini

https://doi.org/10.1021/jm800400k Actions
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