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Deep learning-based molecular dynamics simulation for structure-based drug design against SARS-CoV-2

JOURNAL ARTICLE published 2022 in Computational and Structural Biotechnology Journal

Authors: Yao Sun | Yanqi Jiao | Chengcheng Shi | Yang Zhang

EccBase: A high-quality database for exploration and characterization of extrachromosomal circular DNAs in cancer

JOURNAL ARTICLE published 2023 in Computational and Structural Biotechnology Journal

Authors: Haiyang Sun | Xinyi Lu | Lingyun Zou

The impact of noise and missing fragmentation cleavages on de novo peptide identification algorithms

JOURNAL ARTICLE published 2022 in Computational and Structural Biotechnology Journal

Research funded by Irish Research Council (GOIPG/2019/1650)

Authors: Kevin McDonnell | Enda Howley | Florence Abram

Prospective bacterial and fungal sources of hyaluronic acid: A review

JOURNAL ARTICLE published 2022 in Computational and Structural Biotechnology Journal

Authors: E.V. Shikina | R.A. Kovalevsky | A.I. Shirkovskaya | Ph.V. Toukach

Automated machine learning in nanotoxicity assessment: A comparative study of predictive model performance

JOURNAL ARTICLE published December 2024 in Computational and Structural Biotechnology Journal

Authors: Xiao Xiao | Tung X. Trinh | Zayakhuu Gerelkhuu | Eunyong Ha | Tae Hyun Yoon

Streptomyces coelicolor macrodomain hydrolase SCO6735 cleaves thymidine-linked ADP-ribosylation of DNA

JOURNAL ARTICLE published 2022 in Computational and Structural Biotechnology Journal

Authors: Andrea Hloušek-Kasun | Petra Mikolčević | Johannes Gregor Matthias Rack | Callum Tromans-Coia | Marion Schuller | Gytis Jankevicius | Marija Matković | Branimir Bertoša | Ivan Ahel | Andreja Mikoč

CRISPR/Cas9 based genome editing for targeted transcriptional control in triple-negative breast cancer

JOURNAL ARTICLE published 2021 in Computational and Structural Biotechnology Journal

Authors: Desh Deepak Singh | Ihn Han | Eun-Ha Choi | Dharmendra Kumar Yadav

APPROACHES TO ENGINEER STABILITY OF BEETLE LUCIFERASES

JOURNAL ARTICLE published September 2012 in Computational and Structural Biotechnology Journal

Research funded by Russian Foundation for Basic Research ((grant 08-04-00624 and 11-04-00698))

Authors: Mikhail I. Koksharov | Natalia N. Ugarova

Modelling of pH-dependence to develop a strategy for stabilising mAbs at acidic steps in production

JOURNAL ARTICLE published 2020 in Computational and Structural Biotechnology Journal

Research funded by Engineering and Physical Sciences Research Council (EP/N024796/1)

Authors: Max Hebditch | Ryan Kean | Jim Warwicker

Fever temperatures modulate intraprotein dynamics and enhance the binding affinity between monoclonal antibodies and the spike protein from SARS-CoV-2

JOURNAL ARTICLE published 2022 in Computational and Structural Biotechnology Journal

Research funded by National Supercomputing Center, Korea Institute of Science and Technology Information (KSC-2020-CRE-0203) | Chonnam National University (2022-2574)

Authors: Dong Gun Kim | Hak Sung Kim | Yoonjoo Choi | Razvan Costin Stan

Immunopathology, host-virus genome interactions, and effective vaccine development in SARS-CoV-2

JOURNAL ARTICLE published 2020 in Computational and Structural Biotechnology Journal

Authors: Desh Deepak Singh | Ihn Han | Eun-Ha Choi | Dharmendra Kumar Yadav

Structural insight into the macrocyclic inhibitor TPX-0022 of c-Met and c-Src

JOURNAL ARTICLE published 2023 in Computational and Structural Biotechnology Journal

Research funded by Natural Science Foundation of Hunan Province (2018TP1017,2023JJ20092,2023JJ40954) | National Natural Science Foundation of China (31900880,81570537,81974074,82202920,82273496) | Department of Science and Technology of Hunan Province (2018RS3026,2021RC4012) | Central South University (2023CXQD076) | China Postdoctoral Science Foundation (2019M652805)

Authors: Lingzhi Qu | Hang Lin | Shuyan Dai | Ming Guo | Xiaojuan Chen | Longying Jiang | Huajun Zhang | Maoyu Li | Xunjun Liang | Zhuchu Chen | Hudie Wei | Yongheng Chen

Improving antibody optimization ability of generative adversarial network through large language model

JOURNAL ARTICLE published 2023 in Computational and Structural Biotechnology Journal

Authors: Wenbin Zhao | Xiaowei Luo | Fan Tong | Xiangwen Zheng | Jing Li | Guangyu Zhao | Dongsheng Zhao

IMFSegNet: Cost-effective and objective quantification of intramuscular fat in histological sections by deep learning

JOURNAL ARTICLE published 2023 in Computational and Structural Biotechnology Journal

Research funded by Bundesministerium für Bildung und Forschung (13N15709)

Authors: Jan-Philipp Praetorius | Kassandra Walluks | Carl-Magnus Svensson | Dirk Arnold | Marc Thilo Figge

Caffeine causes cell cycle arrest at G0/G1 and increases of ubiquitinated proteins, ATP and mitochondrial membrane potential in renal cells

JOURNAL ARTICLE published 2023 in Computational and Structural Biotechnology Journal

Authors: Rattiyaporn Kanlaya | Chonnicha Subkod | Supanan Nanthawuttiphan | Visith Thongboonkerd

TWN-FS method: A novel fragment screening method for drug discovery

JOURNAL ARTICLE published 2023 in Computational and Structural Biotechnology Journal

Research funded by Ministry of Science, ICT and Future Planning (NRF-2020R1A2C100691511)

Authors: Hye Ree Yoon | Gyoung Jin Park | Anand Balupuri | Nam Sook Kang

CCLHunter: An efficient toolkit for cancer cell line authentication

JOURNAL ARTICLE published 2023 in Computational and Structural Biotechnology Journal

Research funded by National Natural Science Foundation of China (31970634,32170669) | Chinese Academy of Sciences (XDB38030400) | Youth Innovation Promotion Association of the Chinese Academy of Sciences (2022098) | National Key Research and Development Program of China (2020YFA0907001)

Authors: Congfan Bu | Xinchang Zheng | Jialin Mai | Zhi Nie | Jingyao Zeng | Qiheng Qian | Tianyi Xu | Yanling Sun | Yiming Bao | Jingfa Xiao

Data pre-processing for analyzing microbiome data – A mini review

JOURNAL ARTICLE published 2023 in Computational and Structural Biotechnology Journal

Authors: Ruwen Zhou | Siu Kin Ng | Joseph Jao Yiu Sung | Wilson Wen Bin Goh | Sunny Hei Wong

The chromatin remodeling factors EP300 and TRRAP are novel SMYD3 interactors involved in the emerging ‘nonmutational epigenetic reprogramming’ cancer hallmark

JOURNAL ARTICLE published 2023 in Computational and Structural Biotechnology Journal

Authors: Candida Fasano | Martina Lepore Signorile | Elisabetta Di Nicola | Antonino Pantaleo | Giovanna Forte | Katia De Marco | Paola Sanese | Vittoria Disciglio | Valentina Grossi | Cristiano Simone

Biomarker discovery process at binomial decision point (2BDP): Analytical pipeline to construct biomarker panel

JOURNAL ARTICLE published 2023 in Computational and Structural Biotechnology Journal

Authors: Nabarun Chakraborty | Alexander Lawrence | Ross Campbell | Ruoting Yang | Rasha Hammamieh