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Trifluoromethylated Flavonoid-Based Isoxazoles as Antidiabetic and Anti-Obesity Agents: Synthesis, In Vitro α-Amylase Inhibitory Activity, Molecular Docking and Structure–Activity Relationship Analysis

JOURNAL ARTICLE published 27 August 2021 in Molecules

Authors: Faisal K. Algethami | Ilyes Saidi | Hani Nasser Abdelhamid | Mohamed R. Elamin | Babiker Y. Abdulkhair | Amani Chrouda | Hichem Ben Jannet

Enrichment and Purification of Polyphenol Extract from Sphallerocarpus gracilis Stems and Leaves and in Vitro Evaluation of DNA Damage-Protective Activity and Inhibitory Effects of α-Amylase and α-Glucosidase

JOURNAL ARTICLE published 2 December 2015 in Molecules

Authors: Tingting Ma | Xiangyu Sun | Chengrui Tian | Jiyang Luo | Cuiping Zheng | Jicheng Zhan

The Inhibition of α-Glucosidase, α-Amylase and Protein Glycation by Phenolic Extracts of Cotoneaster bullatus, Cotoneaster zabelii, and Cotoneaster integerrimus Leaves and Fruits: Focus on Anti-Hyperglycemic Activity and Kinetic Parameters

JOURNAL ARTICLE published 20 October 2022 in Molecules

Research funded by Medical University of Lodz (503/3-022-01/503-31-001-19-00)

Authors: Agnieszka Kicel | Anna Magiera | Marta Skrzywanek | Mariola Malczuk | Monika Anna Olszewska

Phytochemical Profile, Antioxidant Capacity, α-Amylase and α-Glucosidase Inhibitory Potential of Wild Moroccan Inula viscosa (L.) Aiton Leaves

JOURNAL ARTICLE published 24 May 2021 in Molecules

Authors: Fadoua Asraoui | Ayoub Kounnoun | Francesco Cacciola | Fouad El Mansouri | Imad Kabach | Yassine Oulad El Majdoub | Filippo Alibrando | Katia Arena | Emanuela Trovato | Luigi Mondello | Adnane Louajri

In Vitro Evaluation of α-amylase and α-glucosidase Inhibition of 2,3-Epoxyprocyanidin C1 and Other Constituents from Pterocarpus erinaceus Poir

JOURNAL ARTICLE published 23 December 2022 in Molecules

Authors: Romeo Toko Feunaing | Alfred Ngenge Tamfu | Abel Joel Yaya Gbaweng | Larissa Mekontso Magnibou | Fidele Ntchapda | Celine Henoumont | Sophie Laurent | Emmanuel Talla | Rodica Mihaela Dinica

Inhibitory Effect of Polyphenols from the Whole Green Jackfruit Flour against α-Glucosidase, α-Amylase, Aldose Reductase and Glycation at Multiple Stages and Their Interaction: Inhibition Kinetics and Molecular Simulations

JOURNAL ARTICLE published 14 March 2022 in Molecules

Authors: Tejaswini Maradesha | Shashank M. Patil | Khalid Awadh Al-Mutairi | Ramith Ramu | SubbaRao V. Madhunapantula | Taha Alqadi

Chia (Salvia hispanica L.), a Pre-Hispanic Food in the Treatment of Diabetes Mellitus: Hypoglycemic, Antioxidant, Anti-Inflammatory, and Inhibitory Properties of α-Glucosidase and α-Amylase, and in the Prevention of Cardiovascular Disease

JOURNAL ARTICLE published 13 December 2023 in Molecules

Authors: Rosario Tavera-Hernández | Manuel Jiménez-Estrada | J. Javier Alvarado-Sansininea | Maira Huerta-Reyes

The Application of Ultrasound in Honey: Antioxidant Activity, Inhibitory Effect on α-amylase and α-glucosidase, and In Vitro Digestibility Assessment

JOURNAL ARTICLE published 8 September 2022 in Molecules

Research funded by Consejo Nacional de Ciencia y Tecnología ((PRONAII food sovereignty - project 321293))

Authors: Armando Peláez-Acero | Diana Belem Garrido-Islas | Rafael Germán Campos-Montiel | Lucio González-Montiel | Gabriela Medina-Pérez | Lorena Luna-Rodríguez | Uriel González-Lemus | Antonio de Jesús Cenobio-Galindo

New Biologically Hybrid Pharmacophore Thiazolidinone-Based Indole Derivatives: Synthesis, In Vitro Αlpha-Amylase and Αlpha-Glucosidase Along with Molecular Docking Investigations

JOURNAL ARTICLE published 4 October 2022 in Molecules

Research funded by Umm al-Qura University (22UQU4320141DSR48)

Authors: Shoaib Khan | Shahid Iqbal | Fazal Rahim | Mazloom Shah | Rafaqat Hussain | Hamad Alrbyawi | Wajid Rehman | Ayed A. Dera | Liaqat Rasheed | H. H. Somaily | Rami Adel Pashameah | Eman Alzahrani | Abd-ElAziem Farouk

Chemical Analysis of the Antihyperglycemic, and Pancreatic α-Amylase, Lipase, and Intestinal α-Glucosidase Inhibitory Activities of Cannabis sativa L. Seed Extracts

JOURNAL ARTICLE published 22 December 2023 in Molecules

Research funded by Princess Nourah bint Abdulrahman University (PNURSP2023R141)

Authors: Salima Haddou | Amal Elrherabi | El Hassania Loukili | Rhizlan Abdnim | Asmae Hbika | Mohamed Bouhrim | Omkulthom Al Kamaly | Asmaa Saleh | Abdelaaty A. Shahat | Mohamed Bnouham | Belkheir Hammouti | Abdelkrim Chahine

Discovery of Novel Coumarin Derivatives as Potential Dual Inhibitors against α-Glucosidase and α-Amylase for the Management of Post-Prandial Hyperglycemia via Molecular Modelling Approaches

JOURNAL ARTICLE published 17 June 2022 in Molecules

Authors: Shashank M. Patil | Reshma Mary Martiz | A. M. Satish | Abdullah M. Shbeer | Mohammed Ageel | Mohammed Al-Ghorbani | Lakshmi Ranganatha | Saravanan Parameswaran | Ramith Ramu

Synthesis and Evaluation of Trypanocidal Activity of Chromane-Type Compounds and Acetophenones

JOURNAL ARTICLE published 23 November 2021 in Molecules

Research funded by Departamento Administrativo de Ciencia, Tecnología e Innovación (111571249860 and 061‐2016) | Universidad de Antioquia (111571249860 and 061‐2016)

Authors: Luis A. González | Sara Robledo | Yulieth Upegui | Gustavo Escobar | Wiston Quiñones

Synthesis and Molecular Docking Studies of Alkoxy- and Imidazole-Substituted Xanthones as α-Amylase and α-Glucosidase Inhibitors

JOURNAL ARTICLE published 18 May 2023 in Molecules

Authors: Dolores G. Aguila-Muñoz | Gabriel Vázquez-Lira | Erika Sarmiento-Tlale | María C. Cruz-López | Fabiola E. Jiménez-Montejo | Víctor E. López y López | Carlos H. Escalante | Dulce Andrade-Pavón | Omar Gómez-García | Joaquín Tamariz | Aarón Mendieta-Moctezuma

Five New Pregnane Glycosides from Gymnema sylvestre and Their α-Glucosidase and α-Amylase Inhibitory Activities

JOURNAL ARTICLE published 28 May 2020 in Molecules

Authors: Phan Van Kiem | Duong Thi Hai Yen | Nguyen Van Hung | Nguyen Xuan Nhiem | Bui Huu Tai | Do Thi Trang | Pham Hai Yen | Tran Minh Ngoc | Chau Van Minh | SeonJu Park | Jae Hyuk Lee | Sun Yeou Kim | Seung Hyun Kim

Molecular Docking and Dynamics Simulation of Natural Compounds from Betel Leaves (Piper betle L.) for Investigating the Potential Inhibition of Alpha-Amylase and Alpha-Glucosidase of Type 2 Diabetes

JOURNAL ARTICLE published 15 July 2022 in Molecules

Research funded by University Grants Commission of Bangladesh. Data Availability Statement: Data are a (37.01.0000.073.03.007.20.133)

Authors: Sabbir Ahmed | Md Ali | Rumana Ruma | Shafi Mahmud | Gobindo Paul | Md Saleh | Mohammed Alshahrani | Ahmad Obaidullah | Sudhangshu Biswas | Md Rahman | Md Rahman | Md Islam

Benzimidazole Bearing Thiosemicarbazone Derivatives Act as Potent α-Amylase and α-Glucosidase Inhibitors; Synthesis, Bioactivity Screening and Molecular Docking Study

JOURNAL ARTICLE published 15 October 2022 in Molecules

Research funded by Taif University Researchers (TURSP-2020/111)

Authors: Hayat Ullah | Shoaib Khan | Fazal Rahim | Muhammad Taha | Rashid Iqbal | Maliha Sarfraz | Syed Adnan Ali Shah | Muhammad Sajid | Mohamed F. Awad | Awatif Omran | Marzough Aziz Albalawi | Mahmoud A. Abdelaziz | Azza Al Areefy | Ibrahim Jafri

Novel C-2 Symmetric Molecules as α-Glucosidase and α-Amylase Inhibitors: Design, Synthesis, Kinetic Evaluation, Molecular Docking and Pharmacokinetics

JOURNAL ARTICLE published 17 April 2019 in Molecules

Authors: Danish Shahzad | Aamer Saeed | Fayaz Ali Larik | Pervaiz Ali Channar | Qamar Abbas | Mohamed F. Alajmi | M. Ifzan Arshad | Mauricio F. Erben | Mubashir Hassan | Hussain Raza | Sung-Yum Seo | Hesham R. El-Seedi

Phytochemical Content and Antidiabetic Properties of Most Commonly Used Antidiabetic Medicinal Plants of Kenya

JOURNAL ARTICLE published 20 October 2023 in Molecules

Authors: Felix Wambua Muema | Consolata Nanjala | Millicent Akinyi Oulo | Phurpa Wangchuk

Synthesis of Novel Benzimidazole-Based Thiazole Derivatives as Multipotent Inhibitors of α-Amylase and α-Glucosidase: In Vitro Evaluation along with Molecular Docking Study

JOURNAL ARTICLE published 30 September 2022 in Molecules

Research funded by King Khalid University (RGP.2/167/43) | Taif University (TURSP-2020/67)

Authors: Rafaqat Hussain | Shahid Iqbal | Mazloom Shah | Wajid Rehman | Shoaib Khan | Liaqat Rasheed | Fazal Rahim | Ayed A. Dera | Sana Kehili | Eslam B. Elkaeed | Nasser S. Awwad | Majed A. Bajaber | Mohammed Issa Alahmdi | Hamad Alrbyawi | Hashem O. Alsaab

Synthesis and Biological Evaluation of Spirocyclic Chromane Derivatives as a Potential Treatment of Prostate Cancer

JOURNAL ARTICLE published 25 May 2021 in Molecules

Authors: Li Feng | Shujia Yu | Hai Wang | Shengwei Yang | Xue Li | Hongjuan Dai | Liwen Zhao | Cheng Jiang | Yazhou Wang