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HPLC-Based Metabolomic Analysis and Characterization of Amaranthus cruentus Leaf and Inflorescence Extracts for Their Antidiabetic and Antihypertensive Potential

JOURNAL ARTICLE published 26 April 2024 in Molecules

Research funded by CONAHCYT (FORDECYT-PRONACES-15319/2020)

Authors: Jesús Alfredo Araujo-León | Ivonne Sánchez-del Pino | Rolffy Ortiz-Andrade | Sergio Hidalgo-Figueroa | Areli Carrera-Lanestosa | Ligia Guadalupe Brito-Argáez | Avel González-Sánchez | Germán Giácoman-Vallejos | Oswaldo Hernández-Abreu | Sergio R. Peraza-Sánchez | Andrés Xingú-López | Víctor Aguilar-Hernández

In Silico Analysis: Anti-Inflammatory and α-Glucosidase Inhibitory Activity of New α-Methylene-γ-Lactams

JOURNAL ARTICLE published 25 April 2024 in Molecules

Research funded by CONACyT (305283,778200)

Authors: Alexis Hernández-Guadarrama | Mónica Aideé Díaz-Román | Irma Linzaga-Elizalde | Blanca Eda Domínguez-Mendoza | A. Berenice Aguilar-Guadarrama

Bioactive α-Pyrone Analogs from the Endophytic Fungus Diaporthe sp. CB10100: α-Glucosidase Inhibitory Activity, Molecular Docking, and Molecular Dynamics Studies

JOURNAL ARTICLE published 12 April 2024 in Molecules

Research funded by Hunan Provincial Natural Science Foundation of China grants (2022JJ50294) | Hunan Provincial Department of Education Science Research Project (22B1036) | Hunan University of Medicine High-Level Talent Introduction Startup Funds (202203) | National Innovation and Entrepreneurship Training for University of PRC (S202312214004,202212214002,S202312214006)

Authors: Zhong Wang | Qingxian Ma | Guangling Wu | Yani Zhong | Bin Feng | Pingzhi Huang | Aijie Li | Genyun Tang | Xueshuang Huang | Hong Pu

Understanding Antidiabetic Potential of Oligosaccharides from Red Alga Dulse Devaleraea inkyuleei Xylan by Investigating α-Amylase and α-Glucosidase Inhibition

JOURNAL ARTICLE published 29 March 2024 in Molecules

Authors: Martin Alain Mune Mune | Tadashi Hatanaka | Hideki Kishimura | Yuya Kumagai

Profile of Phenolic Compounds and Antioxidant Activity of Celery (Apium graveolens) Juices Obtained from Pulp after α-Amylase Treatment from Aspergillus oryzae

JOURNAL ARTICLE published 23 March 2024 in Molecules

Research funded by scientific activities of the Institute of Food and Nutrition Technology, University of Rzeszow (500-806-03-01)

Authors: Natalia Szarek | Grażyna Jaworska | Paweł Hanus

Synthesis and Biological Evaluation of New Dihydrofuro[3,2-b]piperidine Derivatives as Potent α-Glucosidase Inhibitors

JOURNAL ARTICLE published 6 March 2024 in Molecules

Research funded by Central Leading Local Science and Technology Development Project of Sichuan Province (2023ZYD0040) | National Natural Science Foundation of China (21672205,21772192) | Western Light Talent Culture Project of CAS (2017XBZG_XBQNXZ_A1_006)

Authors: Haibo Wang | Xiaojiang Huang | Yang Pan | Guoqing Zhang | Senling Tang | Huawu Shao | Wei Jiao

A Recombinant Thermophilic and Glucose-Tolerant GH1 β-Glucosidase Derived from Hehua Hot Spring

JOURNAL ARTICLE published 26 February 2024 in Molecules

Research funded by Yunnan Applied Basic Research Project (202101AU070138) | Cangshan Comprehensive Scientific Investigation in Dali (KY2126109940) | Foundation of Yunnan Province Science and Technology Department (202305AM070003)

Authors: Qian Zhu | Yuying Huang | Zhengfeng Yang | Xingci Wu | Qianru Zhu | Hongzhao Zheng | Dan Zhu | Zhihua Lv | Yirui Yin

Dearomatization of 3-Aminophenols for Synthesis of Spiro[chromane-3,1′-cyclohexane]-2′,4′-dien-6′-ones via Hydride Transfer Strategy-Enabled [5+1] Annulations

JOURNAL ARTICLE published 26 February 2024 in Molecules

Research funded by National Natural Science Foundation of China (22208184,21978144) | Support Plan on Science and Technology for Youth Innovation of Universities in Shandong Province (2019KJM002) | Talents of High Level Scientific Research Foundation (6651118009,6631115015)

Authors: Jia-Cheng Ge | Yufeng Wang | Feng-Wei Guo | Xiangyun Kong | Fangzhi Hu | Shuai-Shuai Li

A New Potent Inhibitor against α-Glucosidase Based on an In Vitro Enzymatic Synthesis Approach

JOURNAL ARTICLE published 16 February 2024 in Molecules

Research funded by The national key research and development program (2020YFA0907903) | ability establishment of sustainable use for valuable Chinese medicine resources (2060302)

Authors: Huanyu Zhang | Xiance Che | Hongyan Jing | Yaowu Su | Wenqi Yang | Rubing Wang | Guoqi Zhang | Jie Meng | Wei Yuan | Juan Wang | Wenyuan Gao

Statistical Characterization of Food-Derived α-Amylase Inhibitory Peptides: Computer Simulation and Partial Least Squares Regression Analysis

JOURNAL ARTICLE published 13 January 2024 in Molecules

Research funded by National Key Research and Development Program of China (2021YFD2100402)

Authors: Wenhui Li | Shangci Yang | Jiulong An | Min Wang | He Li | Xinqi Liu

Evaluating the Antioxidant and Antidiabetic Properties of Medicago sativa and Solidago virgaurea Polyphenolic-Rich Extracts

JOURNAL ARTICLE published 9 January 2024 in Molecules

Research funded by Ministry of Research, Innovation and Digitization, CCCDI-UEFISCDI (PN-III-P2-2.1-PED-2021-1185) | Competitiveness Operational Program, Axis 1, Action 1.2.3 (105535) | Core-Program (PN 7N/23-02-0101/2023)

Authors: Gabriela Paun | Elena Neagu | Andreia Alecu | Camelia Albu | Ana-Maria Seciu-Grama | Gabriel Lucian Radu

In Silico Design, Synthesis, and Evaluation of Novel Enantiopure Isoxazolidines as Promising Dual Inhibitors of α-Amylase and α-Glucosidase

JOURNAL ARTICLE published 6 January 2024 in Molecules

Authors: Fahad Alhawday | Fahad Alminderej | Siwar Ghannay | Bechir Hammami | Abuzar E. A. E. Albadri | Adel Kadri | Kaiss Aouadi

Exploring Antioxidant and α-Glucosidase Inhibitory Activities in Mulberry Leaves (Morus alba L.) across Growth Stages: A Comprehensive Metabolomic Analysis with Chemometrics

JOURNAL ARTICLE published 27 December 2023 in Molecules

Research funded by Natural Science Foundation of Hebei Province (H2021423017,H2022418001) | Key R&D plan of Hebei Province (23372503D,22372503D) | Science and Technology Project of National Administration of Traditional Chinese Medicine (gzy-kjs-2023-029) | S&T Program of Hebei (223777127D,226Z7714G)

Authors: Wenjie Li | Shenghui Hao | Hengyang Li | Qi An | Lina Yang | Bing Guo | Zijing Xue | Yongli Liu | Long Guo | Yuguang Zheng | Dan Zhang

Chemical Analysis of the Antihyperglycemic, and Pancreatic α-Amylase, Lipase, and Intestinal α-Glucosidase Inhibitory Activities of Cannabis sativa L. Seed Extracts

JOURNAL ARTICLE published 22 December 2023 in Molecules

Research funded by Princess Nourah bint Abdulrahman University (PNURSP2023R141)

Authors: Salima Haddou | Amal Elrherabi | El Hassania Loukili | Rhizlan Abdnim | Asmae Hbika | Mohamed Bouhrim | Omkulthom Al Kamaly | Asmaa Saleh | Abdelaaty A. Shahat | Mohamed Bnouham | Belkheir Hammouti | Abdelkrim Chahine

Chia (Salvia hispanica L.), a Pre-Hispanic Food in the Treatment of Diabetes Mellitus: Hypoglycemic, Antioxidant, Anti-Inflammatory, and Inhibitory Properties of α-Glucosidase and α-Amylase, and in the Prevention of Cardiovascular Disease

JOURNAL ARTICLE published 13 December 2023 in Molecules

Authors: Rosario Tavera-Hernández | Manuel Jiménez-Estrada | J. Javier Alvarado-Sansininea | Maira Huerta-Reyes

Chemical Constituents and α-Glucosidase Inhibitory, Antioxidant and Hepatoprotective Activities of Ampelopsis grossedentata

JOURNAL ARTICLE published 5 December 2023 in Molecules

Research funded by Hunan Provincial Department of Education (20C1397) | Hunan University of Chinese Medicine (2022A2-19,2021YX11,202286,2023CX71)

Authors: Qu-Jing Luo | Wen-Chao Zhou | Xin-Yi Liu | Ya-Jie Li | Qing-Ling Xie | Bin Wang | Chao Liu | Wen-Mao Wang | Wei Wang | Xu-Dong Zhou

Salazinic Acid and Norlobaridone from the Lichen Hypotrachyna cirrhata: Antioxidant Activity, α-Glucosidase Inhibitory and Molecular Docking Studies

JOURNAL ARTICLE published 29 November 2023 in Molecules

Authors: Tatapudi Kiran Kumar | Bandi Siva | Basani Kiranmai | Vidya Jyothi Alli | Surender Singh Jadav | Araveeti Madhusudana Reddy | Joël Boustie | Françoise Le Devehat | Ashok Kumar Tiwari | Katragadda Suresh Babu

HPLC-DAD-MS Characterization, Antioxidant Activity, α-amylase Inhibition, Molecular Docking, and ADMET of Flavonoids from Fenugreek Seeds

JOURNAL ARTICLE published 27 November 2023 in Molecules

Research funded by Deputyship for Research & Innovation, Ministry of Education in Saudi Arabia (IFP-IMSIU-2023015)

Authors: Mohammed Lamine Khenifi | Talia Serseg | Piotr Migas | Mirosława Krauze-Baranowska | Sadin Özdemir | Chawki Bensouici | Mohammed I. Alghonaim | Khattab Al-Khafaji | Sulaiman A. Alsalamah | Messaoud Boudjeniba | Mohamed Yousfi | Fehmi Boufahja | Hamdi Bendif | Mohamed Mahdid

In Vitro Antibacterial, Antioxidant, Anticholinesterase, and Antidiabetic Activities and Chemical Composition of Salvia balansae

JOURNAL ARTICLE published 27 November 2023 in Molecules

Research funded by Ministry of Education in Saudi Arabia (IFP-IMSIU-2023020)

Authors: Amırat Mokhtar | Tabak Souhila | Bouriah Nacéra | Benabdallah Amina | Mohammed I. Alghonaim | Mehmet Öztürk | Sulaiman A. Alsalamah | Mohamed Djamel Miara | Fehmi Boufahja | Hamdi Bendif

The Conformational Change of the L3 Loop Affects the Structural Changes in the Substrate Binding Pocket Entrance of β-Glucosidase

JOURNAL ARTICLE published 27 November 2023 in Molecules

Research funded by National Research Foundation of Korea (NRF-2017M3A9F6029736,NRF-2021R1I1A1A01050838) | Korea Initiative for Fostering University of Research and Innovation (NRF-2020M3H1A1075314) | ProGen (ProGen)

Authors: Ki Hyun Nam