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α-Glucosidase inhibitory potential of Oroxylum indicum using molecular docking, molecular dynamics, and in vitro evaluation

JOURNAL ARTICLE published June 2024 in Saudi Pharmaceutical Journal

Research funded by Department of Biotechnology, Ministry of Science and Technology, India (HRD-11011/32/2021-HRD-DBT)

Authors: Samhita Bhaumik | Alekhya Sarkar | Sudhan Debnath | Bimal Debnath | Rajat Ghosh | Magdi E.A. Zaki | Sami A. Al-Hussain

The amelioration effect of antidiabetic agents on cytokine expression in patients with type 2 diabetes mellitus

JOURNAL ARTICLE published May 2024 in Saudi Pharmaceutical Journal

Authors: Abeer M. Abd El-Hameed | Areej A. Eskandrani | Eman Salah Abdel-Reheim | Adel Abdel Moneim | Wessam Addaleel

α-Glucosidase, butyrylcholinesterase and acetylcholinesterase inhibitory activities of phenolic compounds from Carthamus tinctorius L. flowers: In silico and in vitro studies

JOURNAL ARTICLE published May 2024 in Saudi Pharmaceutical Journal

Research funded by King Abdulaziz University (RG-41-166-43)

Authors: Jawaher A.M. Alotaibi | Alaa Sirwi | Ali M. El-Halawany | Ahmed Esmat | Gamal A. Mohamed | Sabrin R.M. Ibrahim | Abdulrahim A. Alzain | Taher F. Halawa | Martin Safo | Hossam M. Abdallah

Exploring the therapeutic potential of Derris elliptica (Wall.) Benth in Streptozotocin-Induced diabetic Rats: Phytochemical characterization and antidiabetic evaluation

JOURNAL ARTICLE published April 2024 in Saudi Pharmaceutical Journal

Authors: Rassheda Abd Rahman | Hanish Singh Jayasingh Chellammal | Syed Adnan Ali Shah | Rozaini Mohd Zohdi | Dhani Ramachandran | Hannis Fadzillah Mohsin

Preparation and evaluation of antidiabetic activity of mangiferin-loaded solid lipid nanoparticles

JOURNAL ARTICLE published April 2024 in Saudi Journal of Biological Sciences

Authors: Ahmed I. Foudah | Mohammad Ayman Salkini | Mohammed H. Alqarni | Aftab Alam

α-glucosidase and α-amylase inhibitory activity of flavonols from Stenochlaena palustris (Burm.f.) Bedd

JOURNAL ARTICLE published February 2024 in Saudi Pharmaceutical Journal

Research funded by Kementerian Riset, Teknologi dan Pendidikan Tinggi (11320/UN19.5.1.3/AL.04/2023)

Authors: Rudi Hendra | Monika Kerry Army | Neni Frimayanti | Hilwan Yuda Teruna | Rizky Abdulah | Ari Satia Nugraha

Identification of antidiabetic inhibitors from Allophylus villosus and Mycetia sinensis by targeting α-glucosidase and PPAR-γ: In-vitro, in-vivo, and computational evidence

JOURNAL ARTICLE published January 2024 in Saudi Pharmaceutical Journal

Authors: Md Nur Kabidul Azam | Partha Biswas | Md. Mohaimenul Islam Tareq | Md Ridoy Hossain | Shabana Bibi | Md. Anisul Hoque | Amia khandker | Md Ashraful Alam | Md. Nazmul Hasan Zilani | Mohammad Shahedur Rahman | Norah A. Albekairi | Abdulrahman Alshammari | Md. Nazmul Hasan

In vitro anti-inflammatory, antidiabetic, antibacterial, and in silico studies of Ferruginan A isolated from Olea ferruginea Royle (Oleaceae)

JOURNAL ARTICLE published December 2023 in Saudi Pharmaceutical Journal

Research funded by King Abdulaziz University (IFPIP:988–130-1443)

Authors: Abdur Rauf | Bassam Oudh Aljohny | Umer Rashid | Yasir Anwar | Zafar Ali Shah | Naveed Muhammad | Anees Ahmed Khalil | Ahood Khalid | Gauhar Rehman

Multi-target action of Garcinia livingstonei extract and secondary metabolites against fatty acid synthase, α-glucosidase, and xanthine oxidase

JOURNAL ARTICLE published October 2023 in Saudi Pharmaceutical Journal

Authors: Azza M. Abdul-Rahman | Ahlam Elwekeel | Reem S. Alruhaimi | Emadeldin M. Kamel | Albandari Bin-Ammar | Ayman M. Mahmoud | Abeer S. Moawad | Mohamed A. Zaki

Potential antioxidant, anticholinergic, antidiabetic and antiglaucoma activities and molecular docking of spiraeoside as a secondary metabolite of onion (Allium cepa)

JOURNAL ARTICLE published October 2023 in Saudi Pharmaceutical Journal

Authors: Lokman Durmaz | Hatice Kiziltas | Hasan Karagecili | Saleh Alwasel | İlhami Gulcin

Exploring Kinnow mandarin's hidden potential: Nature's key to antimicrobial and antidiabetic gold nanoparticles (K-AuNPs)

JOURNAL ARTICLE published October 2023 in Saudi Journal of Biological Sciences

Research funded by University of Hail (RG-23 146)

Authors: Amjad R. Alyahyawi | Salman Khan | Zeeshan Rafi | Parul Singh | Kahkashan Moheet | Rihab Akasha | Saheem Ahmad

In-vitro and ex-vivo antidiabetic, and antioxidant activities of Box-Behnken design optimized Solanum xanthocarpum extract loaded niosomes

JOURNAL ARTICLE published October 2023 in Saudi Pharmaceutical Journal

Research funded by Ministry of Education – Kingdom of Saudi Arabi (IFKSUOR3-375-1)

Authors: Rama Tyagi | Ayesha Waheed | Neeraj Kumar | Mohd. Mujeeb | Tanveer Naved | Mohammad Rashid Khan | Khaled Alhosaini | Yasser A. Alqarni | Rani Rahat | Perwez Alam | Swati Madan

The α-glucosidase inhibitory activity of avicularin and 4-O-methyl gallic acid isolated from Syzygium myrtifolium leaves

JOURNAL ARTICLE published August 2023 in Saudi Pharmaceutical Journal

Authors: Islan Nor | Komar Ruslan Wirasutisna | Rika Hartati | Muhamad Insanu

In vitro evaluation of novel mefenamic acid derivatives as potential α-glucosidase and urease inhibitors: Design, synthesis, in silico and cytotoxic studies

JOURNAL ARTICLE published July 2023 in Journal of Saudi Chemical Society

Research funded by Princess Nourah Bint Abdulrahman University (RSPD2023R620)

Authors: Saima Daud | Obaid-ur-Rahman Abid | Wajid Rehman | Maryam Niaz | Asma Sardar | Liaqat Rasheed | Basit Niaz | Basit Ali Shah | Hadil Faris Alotaibi | Ahmad J. Obaidullah | Mohammed M. Alanazi

In vitro alpha-amylase and alpha-glucosidase inhibitory activity and in vivo antidiabetic activity of Quercus coccifera (Oak tree) leaves extracts

JOURNAL ARTICLE published July 2023 in Saudi Journal of Biological Sciences

Authors: Saif Aldeen Jaber

Identification of novel oxadiazole-based benzothiazole derivatives as potent inhibitors of α-glucosidase and urease: Synthesis, in vitro bio-evaluation and their in silico molecular docking study

JOURNAL ARTICLE published July 2023 in Journal of Saudi Chemical Society

Research funded by King Saud University (RSPD2023R628)

Authors: Yousaf Khan | Aneela Maalik | Wajid Rehman | Rafaqat Hussain | Shoaib Khan | Mohammed M. Alanazi | Hanadi H Asiri | Shahid Iqbal

The antidiabetic effect of methanolic extract of Holarrhena pubescens seeds is mediated through multiple mechanisms of action

JOURNAL ARTICLE published June 2023 in Saudi Pharmaceutical Journal

Research funded by Shaqra University (SU-ANN-202228)

Authors: AbdulRahman A I Alyahya | Mohammed Asad | Mohammed Sanad Alhussaini | Kamal Eldin Ahmed Abdelsalam | Essa Awad Alenezi

Estimating the potential economic impact of the Wasfaty program on costs of antidiabetic treatment: An initiative for the digital transformation of health

JOURNAL ARTICLE published June 2023 in Saudi Pharmaceutical Journal

Authors: Thamir M. Alshammari | Saud I. Alsubait | Khalidah A. Alenzi | Ziyad S. Almalki

Phytochemical screening and metabolomic approach based on Fourier transform infrared (FTIR): Identification of α-amylase inhibitor metabolites in Vernonia amygdalina leaves

JOURNAL ARTICLE published November 2022 in Journal of Saudi Chemical Society

Authors: Norainny Yunitasari | Respati Tri Swasono | Harno Dwi Pranowo | Tri Joko Raharjo

Reusability of immobilized β-glucosidase on sodium alginate-coated magnetic nanoparticles and high productivity applications

JOURNAL ARTICLE published September 2022 in Journal of Saudi Chemical Society

Authors: Fawze Alnadari | Yemin Xue | Nouf H. Alsubhi | Soha A. Alamoudi | Afaf S. Alwabli | Diana A. Al-Quwaie | Yahya Saud Hamed | Mustapha Muhammad Nasiru | Alia A.M. Ebrahim | Mohamed T. El-Saadony | Fei Pan