Endophytic fungi-assisted biomass synthesis of eco-friendly formulated silver nanoparticles for enhanced antibacterial, antioxidant, and antidiabetic activities

JOURNAL ARTICLE published August 2024 in Journal of Drug Delivery Science and Technology

Research funded by King Saud University (RSP2024R352)

Authors: Frazer Andrade | Christopher Jenipher | Nilambari Gurav | Sameer Nadaf | Mohd Shahnawaz Khan | Nilesh Mahajan | Durgacharan Bhagwat | Mohan Kalaskar | Rupesh Chikhale | Ritesh Bhole | Sulabha Lalsare | Akshay Baheti | Muniappan Ayyanar | Shailendra Gurav

Synthesis and biological (in vitro and in silico) screening of the 4-aryl-fused pyranopyrazole derivatives as enzyme (α-amylase, α-glucosidase, acetylcholinesterase & proteinase) inhibitors with anti-oxidant and cytotoxic activities

JOURNAL ARTICLE published August 2024 in Journal of Molecular Structure

Authors: Nagwa M. Abdelazeem | Wael Mahmoud Aboulthana | Zeinab A. Elshahid | Marwa El-Hussieny | Aisha A.K. Al-Ashmawy

Retrogradation inhibition of starches in staple foods with maltotetraose-forming amylase

JOURNAL ARTICLE published August 2024 in Food Chemistry

Authors: Yunlong Cui | Xueting Li | Dengyue Sun | Li Guo | Bo Cui | Feixue Zou | Jinpeng Wang | Chunrui Sun

1,2,3-Triazole-based betulinic acid derivatives as α-glucosidase inhibitors: Synthesis and in vitro and in vivo biological evaluation

JOURNAL ARTICLE published August 2024 in Journal of Molecular Structure

Authors: Yufei Zhang | Jiangyi Li | Xiaofeng Min | Bingwen Liang | Jinping Sun | Keyin Lin | Zhuang Xiong | Xuetao Xu | Wen-Hua Chen

Discovery of novel 6-(piperidin-1-ylsulfonyl)-2H-chromenes targeting α-glucosidase, α-amylase, and PPAR-γ: Design, synthesis, virtual screening, and anti-diabetic activity for type 2 diabetes mellitus

JOURNAL ARTICLE published August 2024 in Computational Biology and Chemistry

Authors: Hamdy Khamees Thabet | Moustafa S. Abusaif | Mohd Imran | Mohamed Hamdy Helal | Saleh Ibrahim Alaqel | Ahmed Alshehri | Abida Ash Mohd | Yousry A. Ammar | Ahmed Ragab

Exploring the anti-inflammatory, sedative, antidiabetic, and antioxidant potential in in-vitro and in-vivo models and phenolic profiling of Atractylis aristata Batt.

JOURNAL ARTICLE published August 2024 in Journal of Ethnopharmacology

Authors: Asma Abid | Zahnit Wafa | Mahdi Belguidoum | Tatou Touahria | Nour Elhouda Mekhadmi | Messaouda Dekmouche | Lazhar Bechki | Kamilia Bireche | Walid Boussebaa | Ammar AL-Farga

“GC-MS profiling, sub-acute toxicity study and total phenolic and flavonoid content analysis of methanolic leaf extract of Schima wallichii (D.C.) Korth-a traditional antidiabetic medicinal plant”

JOURNAL ARTICLE published August 2024 in Journal of Ethnopharmacology

Authors: Maibam Beebina Chanu | Wahengbam Kabita Chanu | Brajakishor Singh Chingakham

Indolyl imine compounds as multi-target agents; synthesis, antidiabetic, anticholinesterase, antioxidant activities and molecular modeling

JOURNAL ARTICLE published August 2024 in Journal of Molecular Structure

Research funded by Gebze Technical University (2021-A101-04)

Authors: Sadık M. Ceyhan | İrem Nur Zengin | Murat Bingul | Hasan Sahin | Mehmet Boga | Mehmet F. Saglam | Hakan Kandemir | Ibrahim F. Sengul

Chemical stability of carboxylpyranocyanidin-3-O-glucoside under β-glucosidase treatment and description of their interaction

JOURNAL ARTICLE published July 2024 in Food Chemistry

Authors: Kailan Yuan | Xusheng Li | Yingyu Zeng | Chuqi Liu | Yuanqin Zhu | Jun Hu | Jianxia Sun | Weibin Bai

Phenolic constituents with potent α-glucosidase inhibitory and cytotoxic activities from Rumex nepalensis var. remotiflorus

JOURNAL ARTICLE published July 2024 in Phytochemistry

Research funded by Ministry of Science and Technology of the People's Republic of China (2021YFE0103600)

Authors: Jing-Juan Li | Xin-Xin Wang | Yuan-Meng Li | Na Li | Hong-Tao Zhu | Komila Alibekovna Eshbakova | Ying-Jun Zhang

Sulfonylureas exert antidiabetic action on adipocytes by inhibition of PPARγ serine 273 phosphorylation

JOURNAL ARTICLE published July 2024 in Molecular Metabolism

Research funded by German Research Foundation (450149205-TRR333)

Authors: Bodo Haas | Moritz David Sebastian Hass | Alexander Voltz | Matthias Vogel | Julia Walther | Arijit Biswas | Daniela Hass | Alexander Pfeifer

Sensitive and label-free SPR biosensing platforms for high-throughput screening of plasma membrane receptors interactions with insulin-like targets of hypoglycaemic activity

JOURNAL ARTICLE published July 2024 in Talanta

Authors: Marcin Drozd | Ewa Kobylska | Małgorzata Żmieńko | Michał Chudy

Rapid screening of potential α-glucosidase inhibitors from the waste leaves of Rheum tanguticum by activity-oriented extraction and enrichment optimization, UPLC-QTOF-MS/MS, molecular docking and in vitro validation

JOURNAL ARTICLE published July 2024 in Microchemical Journal

Authors: Weihang Lu | Tao Chen | Cheng Shen | Denglang Zou | Juyuan Luo | Shuo Wang | Zhibo Song | Jing Jia | Yulin Li

Cross-linked α-amylase aggregates on Fe3O4 magnetic nanoparticles modified with polydopamine/polyethyleneimine for efficient hydrolysis of starch

JOURNAL ARTICLE published July 2024 in Particuology

Authors: Jiandong Cui | Xiuming Tang | Qingqing Ma | Yuyan Chang | Qunli Zhang | Shiru Jia

In silico studies of Ruellia tuberosa L. compounds as aldose reductase, dipeptidyl peptidase 4, and α-glucosidase inhibitors against type 2 diabetes mellitus

JOURNAL ARTICLE published 1 July 2024 in Journal of Pharmacy & Pharmacognosy Research

Authors: Ekowati Retnaningtyas | Andri Setiawan | Budi Susatia | Tanto Hariyanto | Ni Luh Putu Eka Sudiwati

Pilot market surveillance of GMM contaminations in alpha-amylase food enzyme products: A detection strategy strengthened by a newly developed qPCR method targeting a GM Bacillus licheniformis producing alpha-amylase

JOURNAL ARTICLE published July 2024 in Food Chemistry: Molecular Sciences

Research funded by FOD Volksgezondheid, Veiligheid van de Voedselketen en Leefmilieu (RT 17/5 SPECENZYM)

Authors: Marie-Alice Fraiture | Andrea Gobbo | Chloé Guillitte | Ugo Marchesi | Daniela Verginelli | Joke De Greve | Jolien D'aes | Kevin Vanneste | Nina Papazova | Nancy H.C. Roosens

Synthesis and characterization of some novel benzoyl thioureas as potent α-glucosidase inhibitors: In vitro and in silico

JOURNAL ARTICLE published July 2024 in Journal of Molecular Structure

Authors: Muhammad Azeem Shakil | Saeed Ullah | Sobia Ahsan Halim | Khalid Mahmood | Muhammad Hanif | Muhammad Khalid | Ajaz Hussain | Faizullah Khan | Ataf Ali Altaf | Muhammad Rashid | Ajmal Khan | Muhammad U. Anwar | Ahmed Al-Harrasi

Milk casein hydrolysate peptides regulate starch digestion through inhibition of α-glucosidase: An insight into the active oligopeptide screening, enzyme inhibition behaviors, and oligopeptide-enzyme binding interactions

JOURNAL ARTICLE published July 2024 in Food Hydrocolloids

Authors: Ruibo Cao | Wenyue Li | Jifan Zhang | Xingyu Bao | Haotian Feng | Jiaqi Sun | Xuebo Liu | Lijun Sun

Microbial production of α-amylase from agro-waste: An approach towards biorefinery and bio-economy

JOURNAL ARTICLE published July 2024 in Energy Nexus

Authors: Pramod Kumar Sahu | Renu Singh | Manoj Shrivastava | Sibanada Darjee | Vellaichamy Mageshwaran | Laccy Phurailtpam | Bharti Rohatgi

Response surface methodology as an approach for optimization of alpha amylase production by using bacterial consortium under submerged fermentation

JOURNAL ARTICLE published July 2024 in Kuwait Journal of Science

Authors: Roheena Abdullah | Sitara Ahmad | Kinza Nisar | Afshan Kaleem | Mehwish Iqtedar