Crispr strategies for stem cell engineering: a new frontier in musculoskeletal regeneration

JOURNAL ARTICLE published 22 November 2023 in European Cells and Materials

Authors: JP Graham | LC Werba | I Federico | T Gonzalez-Fernandez

Nicorandil mitigates arthrogenic contracture induced by knee joint extension immobilization in rats: interference with RhoA/ROCK signaling and TGF-β1/Smad pathway

JOURNAL ARTICLE published 15 March 2024 in European Cells and Materials

Authors: XM Li | K Wang | M Liu | QB Zhang | Y Zhou

Intervertebral disc and endplate cell characterisation highlights annulus fibrosus cells as the most promising for tissue-specific disc degeneration therapy

JOURNAL ARTICLE published 3 March 2020 in European Cells and Materials

Authors: P De Luca | IRCCS Istituto Ortopedico Galeazzi, Orthopaedic Biotechnology Lab, Milan, Italy | M Castagnetta | L de Girolamo | S Coco | M Malacarne | E Ragni | M Viganò | G Lugano | M Brayda-Bruno | D Coviello | A Colombini

Designer fat cells: adipogenic differentiation of CRISPR-Cas9 genome-engineered induced pluripotent stem cells

JOURNAL ARTICLE published 29 December 2023 in European Cells and Materials

Authors: EV Ely | AT Kapinski | SG Paradi | R Tang | F Guilak | KH Collins

Potential of Notochordal Cells within Injectable Biomaterials to Promote Intervertebral Disc Regeneration

JOURNAL ARTICLE published 1 March 2024 in European Cells and Materials

Authors: RJ Williams | S Basatvat | TC Schmitz | R Janani | C Sammon | K Benz | K Ito | MA Tryfonidou | JW Snuggs | CL Le Maitre

Gene activated reinforced scaffolds for SOX9 delivery to enhance repair of large load bearing articular cartilage defects

JOURNAL ARTICLE published 27 March 2024 in European Cells and Materials

Authors: M Joyce | T Hodgkinson | C Intini | JE Dixon | DJ Kelly | FJ O'Brien

Establishment of a Coculture System with Osteochondral and Synovial Explants as an Ex Vivo Inflammatory Osteoarthritis Model

JOURNAL ARTICLE published 27 February 2024 in European Cells and Materials

Authors: K Li | Y Zhu | M Alini | MJ Stoddart | S Grad | Z Li

Treatment of volumetric muscle loss in female rats with biomimetic sponges

JOURNAL ARTICLE published 19 October 2023 in European Cells and Materials

Authors: D Johnson | A Dunn | G Haas | J Madsen | J Robinson | C Tobo | N Ziemkiewicz | A Nagarapu | S Shringarpure | K Garg

Single cell multi-omics characterise discrete human tendon cells populations that persist in vitro and on fibrous scaffolds

JOURNAL ARTICLE published 2 August 2022 in European Cells and Materials

Authors: A Gomez-Collignon | R Brown | A Carr | S Dakin | A Lach | C Loizou | M Rogers | R Sharp | A Kendal

Notochordal cell-derived matrix inhibits MAPK signaling in the degenerative disc environment

JOURNAL ARTICLE published 7 November 2023 in European Cells and Materials

Authors: LT Laagland | FC Bach | FM Riemers | G Erdmann | TS Braun | GGH van den Akker | TC Schmitz | LB Creemers | C Sachse | CL Le Maitre | TJM Welting | K Ito | MF Templin | MA Tryfonidou

Relationship between microscale shear modulus, composition, and structure in porcine, canine, and human temporomandibular-joint cartilage: relevance to disease and degeneration

JOURNAL ARTICLE published 1 November 2023 in European Cells and Materials

Authors: D Yoon | S Peralta | N Fiani | GS Reeve | I Cohen | LJ Bonassar

Intervertebral disc degeneration instigates vertebral endplate remodeling and facet joint pathology in a large animal model

JOURNAL ARTICLE published 23 April 2024 in European Cells and Materials

Authors: SE Gullbrand | BS Orozco | M Fainor | K Meadows | R Hilliard | M Boyes | S Mahindroo | RL Mauck | DM Elliott | TP Schaer | HE Smith

AAV-mediated, in vivo gene delivery to the rotator cuff

JOURNAL ARTICLE published 29 December 2023 in European Cells and Materials

Authors: RE Sherwin | EB McGlinch | MA Barry | CM Lopez De Padilla | DR Montonye | CH Evans | A Atasoy-Zeybek

Changes in osteogenesis by human dental pulp stem cells on porcine decellularised adipose tissue solid foams of different porosity

JOURNAL ARTICLE published 28 November 2023 in European Cells and Materials

Authors: Jon Luzuriaga | Nerea García-Urkia | Jone Salvador-Moya | Beatriz Pardo-Rodríguez | Iker Etxebarria | Francisco-Javier Fernandez-San-Argimiro | Beatriz Olalde | Fernando Unda | Jose Ramon Pineda | Iratxe Madarieta | Gaskon Ibarretxe

Creating tissue with intervertebral disc-like characteristics using gdf5 functionalized silk scaffolds and human mesenchymal stromal cells

JOURNAL ARTICLE published 16 October 2023 in European Cells and Materials

Authors: AS Croft | J Fuhrer | M Wöltje | B Gantenbein

Extracellular matrix from hiPSC-mesenchymal progenitors modulates the three-lineage differentiation of human bone marrow stromal cells

JOURNAL ARTICLE published 2 April 2024 in European Cells and Materials

Authors: D Hanetseder | B Schaedl | H Redl | D Marolt Presen

Alginate hydrogel-guided rAAV-mediated FGF-2 and TGF-β delivery and overexpression stimulates the biological activities of human meniscal fibrochondrocytes for meniscus repair

JOURNAL ARTICLE published 21 February 2024 in European Cells and Materials

Authors: JK Venkatesan | W Liu | H Madry | M Cucchiarini

Fast and non-viral method to deliver plasmid DNA to human muscle-tendon graft used in anterior cruciate ligament reconstruction

JOURNAL ARTICLE published 5 December 2023 in European Cells and Materials

Authors: A Šećerović | B Markelc | I Matić | A Frischer | A Hacobian | T Jesenko | M Cemazar | H Redl | D Marolt Presen | A Ivković

A novel mouse model of polytrauma with spinal cord injury–associated heterotopic ossification

JOURNAL ARTICLE published 21 March 2024 in European Cells and Materials

Authors: R Aita | G Unnithan | T Klaylat | JA Petruccelli | G St-Jean | M Radhakrishna | R Gawri | C Gao

Burn-Synovectomy Mouse Model for Temporomandibular Joint Osteoarthritis

JOURNAL ARTICLE published 5 March 2024 in European Cells and Materials

Authors: Ginny Ching-Yun Hsu