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Hedgehog inhibits β-catenin activity in synovial joint development and osteoarthritis JOURNAL ARTICLE published 28 March 2016 in Journal of Clinical Investigation |
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Histone methyltransferase SETD2 modulates alternative splicing to inhibit intestinal tumorigenesis JOURNAL ARTICLE published 21 August 2017 in Journal of Clinical Investigation Research funded by the Strategic Priority Research Program of the Chinese Academy of Sciences (XDB19000000) | the National Natural Science Foundation of China (31471281) | the National Natural Science Foundation of China (81422030) | the National Key Basic Research Program (2016YFC0902202) |
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Transplacental immune modulation with a bacterial-derived agent protects against allergic airway inflammation JOURNAL ARTICLE published 2 October 2018 in Journal of Clinical Investigation Research funded by National Health and Medical Research Council (App 1047212) |
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Androgen receptor activity in prostate cancer dictates efficacy of bipolar androgen therapy through MYC JOURNAL ARTICLE published 1 December 2022 in Journal of Clinical Investigation Research funded by Department of Defense (W81XWH2010079) | Department of Defense (W81XWH-22-1-0118) | Department of Defense (W81XWH1910724) | Johns Hopkins University (Clinician-Scientist Award) | Prostate Cancer Foundation (Young Investigator Award) | Prostate Cancer Foundation (Challenge Award) | National Institute of Health (1R01CA243184-01A1) | National Institute of Health (P50CA058236) |
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Degradation of GSPT1 causes TP53-independent cell death in leukemia while sparing normal hematopoietic stem cells JOURNAL ARTICLE published 15 August 2022 in Journal of Clinical Investigation Research funded by NIH (P50CA206963) | NIH (R01CA214608) | NIH (P01CA066966) | NIH (R01HL082945) | NIH (P01CA066996) | NIH (CA233691) | NIH (CA236626) |
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The D84G mutation in STIM1 causes nuclear envelope dysfunction and myopathy in mice JOURNAL ARTICLE published 1 April 2024 in Journal of Clinical Investigation Research funded by NIH-NIDDK (R01DK109911) | NIH-NIDDK (R01DK109911) |
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Reduced glucose-induced first-phase insulin release is a danger signal that predicts diabetes JOURNAL ARTICLE published 15 June 2021 in Journal of Clinical Investigation |
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Back to the future: evolutionary biology reveals a key regulatory switch in neuroblastoma pathogenesis JOURNAL ARTICLE published 15 May 2023 in Journal of Clinical Investigation |
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Finding a new balance to cure Charcot-Marie-Tooth 2A JOURNAL ARTICLE published 18 March 2019 in Journal of Clinical Investigation |
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Aortic carboxypeptidase–like protein, a WNT ligand, exacerbates nonalcoholic steatohepatitis JOURNAL ARTICLE published 2 April 2018 in Journal of Clinical Investigation Research funded by Grant-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science, and Technology of Japan (15K09031) |
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A conversation with Olufunmilayo Olopade JOURNAL ARTICLE published 16 January 2024 in Journal of Clinical Investigation |
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Lymph node fibroblastic reticular cells deposit fibrosis-associated collagen following organ transplantation JOURNAL ARTICLE published 29 June 2020 in Journal of Clinical Investigation Research funded by National Institutes of Health (RO1AI126596,RO1HL145813,RO1HL141815) | National Institutes of Health (RO1AI062765,RO1 AI14496) |
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The pan-microbiome profiling system Taxa4Meta identifies clinical dysbiotic features and classifies diarrheal disease JOURNAL ARTICLE published 16 January 2024 in Journal of Clinical Investigation Research funded by NIDDK, NIAID, NINR (NIDDK P30-DK56338,R01DK130517,NIAID R01-AI10091401,U01-AI24290,P01-AI152999,,NINR R01-NR013497.) |
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Noggin regulates foregut progenitor cell programming and mis-expression leads to esophageal atresia JOURNAL ARTICLE published 19 May 2020 in Journal of Clinical Investigation Research funded by Department of Veterans Affairs Merit Review (Award (I01 BX000930)) | DOD (CA160479) | NIH (RO1 DK071590) | The Helen and Nicholas Abumrad Research Fund (NA) | NIH (T32 CA106183) | Vanderbilt (VICTR (VR15139.1)) | NIH (R21TR001751) | Emory (Emory Orthopaedics Seed Grant) | Vanderbilt (Vanderbilt Digestive Disease Center,(P30 DK058404)) |
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Makorin rings the kisspeptin bell to signal pubertal initiation JOURNAL ARTICLE published 20 July 2020 in Journal of Clinical Investigation |
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Active transcription in the vascular bed characterizes rapid progression in idiopathic pulmonary fibrosis JOURNAL ARTICLE published 15 August 2023 in Journal of Clinical Investigation Research funded by National Institutes of Health (1R01HL161620-01A1,OTA-21-015E,1R01HL126596) | Cystic Fibrosis Foundation (MARGAR21F5) | U.S. Department of Veterans Affairs (101CX001969) |
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Rabbit antithymocyte globulin–induced serum sickness disease and human kidney graft survival JOURNAL ARTICLE published 9 November 2015 in Journal of Clinical Investigation |
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Blood-derived lysophospholipid sustains hepatic phospholipids and fat storage necessary for hepatoprotection in overnutrition JOURNAL ARTICLE published 1 September 2023 in Journal of Clinical Investigation Research funded by Ministry of Education, Singapore (MOE-T2EP30220-0001,MOE2019-T2-1-031) | Ministry of Health, Singapore (MOH-000217,MOH-001206,MOH-001234) |
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Cancer immunotherapy needs to learn how to stick to its guns JOURNAL ARTICLE published 11 November 2019 in Journal of Clinical Investigation |
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Integrated host/microbe metagenomics enables accurate lower respiratory tract infection diagnosis in critically ill children JOURNAL ARTICLE published 3 April 2023 in Journal of Clinical Investigation |