Surface-associated antigen induces permeabilization of primary mouse B-cells and lysosome exocytosis facilitating antigen uptake and presentation to T-cells

JOURNAL ARTICLE published 27 October 2021 in eLife

Research funded by National Institutes of Health (R01 GM064625) | National Institutes of Health (T32 GM080201)

Authors: Fernando Y Maeda | Jurriaan JH van Haaren | David B Langley | Daniel Christ | Norma W Andrews | Wenxia Song

Genetic dissection of the RNA polymerase II transcription cycle

JOURNAL ARTICLE published 1 July 2022 in eLife

Research funded by National Human Genome Research Institute (R01-HG010346) | National Human Genome Research Institute (R01-HG009309)

Authors: Shao-Pei Chou | Adriana K Alexander | Edward J Rice | Lauren A Choate | Charles G Danko

Transcription of a 5’ extended mRNA isoform directs dynamic chromatin changes and interference of a downstream promoter

JOURNAL ARTICLE published 14 September 2017 in eLife

Research funded by Francis Crick Institute (FC001203) | Pew Charitable Trusts (00027344) | March of Dimes Foundation (5-FY15-99) | National Science Foundation (DGE-1106400 Graduate Student Fellowship) | Agency for Science, Technology and Research (Graduate Student Fellowship)

Authors: Minghao Chia | Amy Tresenrider | Jingxun Chen | Gianpiero Spedale | Victoria Jorgensen | Elçin Ünal | Folkert Jacobus van Werven

Tuberculosis-associated IFN-I induces Siglec-1 on tunneling nanotubes and favors HIV-1 spread in macrophages

JOURNAL ARTICLE published 30 March 2020 in eLife

Research funded by Agence Nationale de Recherches sur le Sida et les Hépatites Virales (ANRS2014-049) | Agence Nationale de Recherches sur le Sida et les Hépatites Virales (ANRS2020-01) | Agence Nationale de Recherches sur le Sida et les Hépatites Virales (ANRS2018-01) | Agence Nationale de la Recherche (ANR-11-EQUIPEX-0003) | Agence Nationale de la Recherche (ANR16-CE13-0005-01) | Fondation pour la Recherche Médicale (DEQ20160334902) | Fondation pour la Recherche Médicale (DEQ2016 0334894) | ECOS-Sud program (A14S01) | Human Frontier Science Program (RGP0035/2016) | National Agency for Science and Technology, Argentina (PICT-2015–0055) | National Agency for Science and Technology, Argentina (PICT-2017–1317) | National Institutes of Health (OD011104) | National Institutes of Health (AI111943) | National Institutes of Health (AI097059) | National Institutes of Health (AI110163) | National Institutes of Health (AI111914) | Université Toulouse III - Paul Sabatier (Axes Thématiques Prioritaires doctoral scholarship) | Sidaction (4th year doctoral scholarship) | Centre Hospitalier Universitaire de Toulouse (Master's scholarship) | Ministerio de Economía y Competitividad (Secretariat of State of Research, Development and Innovation SAF2016-80033-R) | Institute of Health Carlos III (CM17/00242)

Authors: Maeva Dupont | Shanti Souriant | Luciana Balboa | Thien-Phong Vu Manh | Karine Pingris | Stella Rousset | Céline Cougoule | Yoann Rombouts | Renaud Poincloux | Myriam Ben Neji | Carolina Allers | Deepak Kaushal | Marcelo J Kuroda | Susana Benet | Javier Martinez-Picado | Nuria Izquierdo-Useros | Maria del Carmen Sasiain | Isabelle Maridonneau-Parini | Olivier Neyrolles | Christel Vérollet | Geanncarlo Lugo-Villarino

Natural variation in autumn expression is the major adaptive determinant distinguishing Arabidopsis FLC haplotypes

JOURNAL ARTICLE published 9 September 2020 in eLife

Research funded by Horizon 2020 Framework Programme (MEXTIM) | Biotechnology and Biological Sciences Research Council (BB/J004588/1) | Biotechnology and Biological Sciences Research Council (BB/P013511/1) | Biotechnology and Biological Sciences Research Council (BB/P003095/1) | Biotechnology and Biological Sciences Research Council (BB/L016079/1)

Authors: Jo Hepworth | Rea L Antoniou-Kourounioti | Kristina Berggren | Catja Selga | Eleri H Tudor | Bryony Yates | Deborah Cox | Barley Rose Collier Harris | Judith A Irwin | Martin Howard | Torbjörn Säll | Svante Holm | Caroline Dean

A protein phosphatase network controls the temporal and spatial dynamics of differentiation commitment in human epidermis

JOURNAL ARTICLE published 18 October 2017 in eLife

Research funded by Wellcome Trust (096540/Z/11/Z) | Medical Research Council (G1100073) | Wellcome Trust (108058/Z/15/Z)

Authors: Ajay Mishra | Bénédicte Oulès | Angela Oliveira Pisco | Tony Ly | Kifayathullah Liakath-Ali | Gernot Walko | Priyalakshmi Viswanathan | Matthieu Tihy | Jagdeesh Nijjher | Sara-Jane Dunn | Angus I Lamond | Fiona M Watt

Size uniformity of animal cells is actively maintained by a p38 MAPK-dependent regulation of G1-length

JOURNAL ARTICLE published 29 March 2018 in eLife

Research funded by Canadian Institutes of Health Research (FRN-343437) | National Institute of General Medical Sciences (GM26875)

Authors: Shixuan Liu | Miriam Bracha Ginzberg | Nish Patel | Marc Hild | Bosco Leung | Zhengda Li | Yen-Chi Chen | Nancy Chang | Yuan Wang | Ceryl Tan | Shulamit Diena | William Trimble | Larry Wasserman | Jeremy L Jenkins | Marc W Kirschner | Ran Kafri

Rem2 stabilizes intrinsic excitability and spontaneous firing in visual circuits

JOURNAL ARTICLE published 29 May 2018 in eLife

Research funded by National Eye Institute (EY022122) | National Institute of Mental Health (K01MH101639) | National Institute of Neurological Disorders and Stroke (R01NS065856) | National Institute of Neurological Disorders and Stroke (Ruth L Kirschstein NIH Training Grant T32NS007292)

Authors: Anna R Moore | Sarah E Richards | Katelyn Kenny | Leandro Royer | Urann Chan | Kelly Flavahan | Stephen D Van Hooser | Suzanne Paradis

Human hippocampal responses to network intracranial stimulation vary with theta phase

JOURNAL ARTICLE published 1 December 2022 in eLife

Research funded by National Institute of Neurological Disorders and Stroke (R01NS113804) | National Institute of Mental Health (F31MH125577)

Authors: Sarah M Lurie | James E Kragel | Stephan U Schuele | Joel L Voss

Repeated losses of PRDM9-directed recombination despite the conservation of PRDM9 across vertebrates

JOURNAL ARTICLE published 6 June 2017 in eLife

Research funded by National Institutes of Health (R01 GM83098) | National Science Foundation (DDIG DEB-1405232)

Authors: Zachary Baker | Molly Schumer | Yuki Haba | Lisa Bashkirova | Chris Holland | Gil G Rosenthal | Molly Przeworski

Hypoxia-induced tracheal elasticity in vector beetle facilitates the loading of pinewood nematode

JOURNAL ARTICLE published 30 March 2023 in eLife

Research funded by National Natural Science Foundation of China (32088102) | National Natural Science Foundation of China (32061123002) | National Key Research and Development Program of China (2021YFC2600100) | National Natural Science Foundation of China (32230066) | National Natural Science Foundation of China (31970466)

Authors: Xuan Tang | Jiao Zhou | Tuuli-Marjaana Koski | Shiyao Liu | Lilin Zhao | Jianghua Sun

Early prediction of clinical response to checkpoint inhibitor therapy in human solid tumors through mathematical modeling

JOURNAL ARTICLE published 9 November 2021 in eLife

Research funded by National Science Foundation (DMS-1930583) | National Institutes of Health (1R01CA253865) | National Institutes of Health (1U01CA196403) | National Institutes of Health (1U01CA213759) | National Institutes of Health (1R01CA226537) | National Institutes of Health (1R01CA222007) | National Institutes of Health (U54CA210181) | National Institutes of Health (P30CA016672) | National Institutes of Health (P30CA072720) | European Commission (SER Cymru II Programme) | National Institutes of Health (U01CA200468) | National Institutes of Health (R01CA222959) | DOD Breast Cancer Research (Breakthrough Level IV Award W81XWH-17-1-0389) | National Institutes of Health (R01CA109322) | National Institutes of Health (R01CA127483) | National Institutes of Health (R01CA208703) | National Institutes of Health (R01CA140243) | National Institutes of Health (R01CA188610)

Authors: Joseph D Butner | Geoffrey V Martin | Zhihui Wang | Bruna Corradetti | Mauro Ferrari | Nestor Esnaola | Caroline Chung | David S Hong | James W Welsh | Naomi Hasegawa | Elizabeth A Mittendorf | Steven A Curley | Shu-Hsia Chen | Ping-Ying Pan | Steven K Libutti | Shridar Ganesan | Richard L Sidman | Renata Pasqualini | Wadih Arap | Eugene J Koay | Vittorio Cristini

Rapid stimulus-driven modulation of slow ocular position drifts

JOURNAL ARTICLE published 6 August 2020 in eLife

Research funded by Deutsche Forschungsgemeinschaft (HA6749/2-1) | Deutsche Forschungsgemeinschaft (EXC307) | Werner Reichardt Centre for Integrative Neuroscience (Mini_GK 2017–04)

Authors: Tatiana Malevich | Antimo Buonocore | Ziad M Hafed

Comprehensive machine-learning survival framework develops a consensus model in large-scale multicenter cohorts for pancreatic cancer

JOURNAL ARTICLE published 25 October 2022 in eLife

Research funded by National Natural Science Foundation of China (81870457) | National Natural Science Foundation of China (82172944)

Authors: Libo Wang | Zaoqu Liu | Ruopeng Liang | Weijie Wang | Rongtao Zhu | Jian Li | Zhe Xing | Siyuan Weng | Xinwei Han | Yu-ling Sun

Interneuronal mechanisms of hippocampal theta oscillations in a full-scale model of the rodent CA1 circuit

JOURNAL ARTICLE published 23 December 2016 in eLife

Research funded by National Institutes of Health (F32NS090753) | National Science Foundation (DGE-0808392) | National Science Foundation (XSEDE Allocations - TG-IBN140007) | National Science Foundation (XSEDE Allocations - TG-IBN130022) | National Science Foundation (XSEDE Allocations - TG-IBN100011) | National Institutes of Health (NS35915) | National Science Foundation (IOS-1310378) | National Institutes of Health (NS090583)

Authors: Marianne J Bezaire | Ivan Raikov | Kelly Burk | Dhrumil Vyas | Ivan Soltesz

Dynein-mediated transport and membrane trafficking control PAR3 polarised distribution

JOURNAL ARTICLE published 23 January 2019 in eLife

Research funded by Fondation ARC pour la Recherche sur le Cancer (SLR20130607102) | Ligue Contre le Cancer (RS14/75-58) | Fondation ARC pour la Recherche sur le Cancer (PJA 20141201756) | Fondation ARC pour la Recherche sur le Cancer (PJA 20161204931)

Authors: Julie Jouette | Antoine Guichet | Sandra B Claret

Developmental evolution of the forebrain in cavefish, from natural variations in neuropeptides to behavior

JOURNAL ARTICLE published 6 February 2018 in eLife

Research funded by Agence Nationale de la Recherche (Blindtest) | Fondation pour la Recherche Médicale (DEQ20150331745 RETAUX)

Authors: Alexandre Alié | Lucie Devos | Jorge Torres-Paz | Lise Prunier | Fanny Boulet | Maryline Blin | Yannick Elipot | Sylvie Retaux

An excitatory amacrine cell detects object motion and provides feature-selective input to ganglion cells in the mouse retina

JOURNAL ARTICLE published 19 May 2015 in eLife

Research funded by National Institutes of Health (NIH) (EY021855) | Research to Prevent Blindness (RPB) (Career Development Award) | National Institutes of Health (NIH) (EY 023341)

Authors: Tahnbee Kim | Florentina Soto | Daniel Kerschensteiner

AANAT1 functions in astrocytes to regulate sleep homeostasis

JOURNAL ARTICLE published 21 September 2020 in eLife

Research funded by Natural Sciences and Engineering Research Council of Canada (RGPIN-2017-05142) | Canadian Institutes of Health Research (MOP-137034) | National Institutes of Health (DK120757)

Authors: Sejal Davla | Gregory Artiushin | Yongjun Li | Daryan Chitsaz | Sally Li | Amita Sehgal | Donald J van Meyel

The untapped potential of medaka and its wild relatives

JOURNAL ARTICLE published 9 July 2019 in eLife

Research funded by Leibniz Association (P91/2016)

Authors: Leon Hilgers | Julia Schwarzer