Evaluation of heterologous prime-boost vaccination strategies using chimpanzee adenovirus and modified vaccinia virus for TB subunit vaccination in rhesus macaques

JOURNAL ARTICLE published 14 May 2020 in npj Vaccines

Authors: Michel P. M. Vierboom | Agnes L. Chenine | Patricia A. Darrah | Richard A. W. Vervenne | Charelle Boot | Sam O. Hofman | Claudia C. Sombroek | Karin Dijkman | Mohamed A. Khayum | Marieke A. Stammes | Krista G. Haanstra | Chantal Hoffmann | Doris Schmitt | Nathalie Silvestre | Alexander G. White | H. Jacob Borish | Robert A. Seder | Nadia Ouaked | Stephane Leung-Theung-Long | Geneviève Inchauspé | Ravi Anantha | Mary Limbach | Thomas G. Evans | Danilo Casimiro | Maria Lempicki | Dominick J. Laddy | Aurelio Bonavia | Frank A. W. Verreck

Adenovectors encoding RSV-F protein induce durable and mucosal immunity in macaques after two intramuscular administrations

JOURNAL ARTICLE published 20 December 2019 in npj Vaccines

Authors: N. C. Salisch | A. Izquierdo Gil | D. N. Czapska-Casey | L. Vorthoren | J. Serroyen | J. Tolboom | E. Saeland | H. Schuitemaker | R. C. Zahn

Memory-like innate response to booster vaccination with MF-59 adjuvanted influenza vaccine in children

JOURNAL ARTICLE published 13 July 2023 in npj Vaccines

Research funded by U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases (U19 AI167903)

Authors: Dmitri Kazmin | Elizabeth A. Clutterbuck | Giorgio Napolitani | Amanda L. Wilkins | Andrea Tarlton | Amber J. Thompson | Emmanuele Montomoli | Guilia Lapini | Smiti Bihari | Rachel White | Claire Jones | Matthew D. Snape | Ushma Galal | Ly-Mee Yu | Rino Rappuoli | Giuseppe Del Giudice | Andrew J. Pollard | Bali Pulendran

Effects of adjuvants in a rabies-vectored Ebola virus vaccine on protection from surrogate challenge

JOURNAL ARTICLE published 8 February 2023 in npj Vaccines

Research funded by Division of Intramural Research, National Institute of Allergy and Infectious Diseases (HHSN272201700082C,R01 AI105204)

Authors: Catherine Yankowski | Drishya Kurup | Christoph Wirblich | Matthias J. Schnell

Inactivated rabies-vectored SARS-CoV-2 vaccine provides long-term immune response unaffected by vector immunity

JOURNAL ARTICLE published 23 September 2022 in npj Vaccines

Research funded by Division of Intramural Research, National Institute of Allergy and Infectious Diseases (R21AI158044)

Authors: Catherine Yankowski | Christoph Wirblich | Drishya Kurup | Matthias J. Schnell

The full health, economic, and social benefits of prospective Strep A vaccination

JOURNAL ARTICLE published 30 October 2023 in npj Vaccines

Research funded by Wellcome Trust (215490/Z/19/Z,215490/Z/19/Z,215490/Z/19/Z,215490/Z/19/Z,215490/Z/19/Z,215490/Z/19/Z,215490/Z/19/Z)

Authors: Daniel Cadarette | Maddalena Ferranna | Jeffrey W. Cannon | Kaja Abbas | Fiona Giannini | Leo Zucker | David E. Bloom

Vaccine-induced time- and age-dependent mucosal immunity to gastrointestinal parasite infection

JOURNAL ARTICLE published 7 July 2022 in npj Vaccines

Research funded by RCUK | Biotechnology and Biological Sciences Research Council (BB/M012956/1,BB/M012956/1,BB/M011968/1,BB/M011968/1,BB/M011968/1,BB/M011968/1,BB/M011968/1)

Authors: Wei Liu | Tom N. McNeilly | Mairi Mitchell | Stewart T. G. Burgess | Alasdair J. Nisbet | Jacqueline B. Matthews | Simon A. Babayan

Reverse development of vaccines against antimicrobial-resistant pathogens

JOURNAL ARTICLE published 3 April 2024 in npj Vaccines

Authors: Fabio Bagnoli | Ilaria Galgani | V. Kumaran Vadivelu | Sanjay Phogat

COVID-19 vaccines: breaking record times to first-in-human trials

JOURNAL ARTICLE published 30 April 2020 in npj Vaccines

Authors: Young Chan Kim | Barbara Dema | Arturo Reyes-Sandoval

Clostridium perfringens epsilon toxin vaccine candidate lacking toxicity to cells expressing myelin and lymphocyte protein

JOURNAL ARTICLE published 30 July 2019 in npj Vaccines

Research funded by RCUK | Biotechnology and Biological Sciences Research Council (BB/N001591/1,BB/N001591/1,BB/N001591/1)

Authors: Helen Morcrette | Monika Bokori-Brown | Stephanie Ong | Leo Bennett | Brendan W. Wren | Nick Lewis | Richard W. Titball

Neutrophil swarming and extracellular trap formation play a significant role in Alum adjuvant activity

JOURNAL ARTICLE published 23 January 2017 in npj Vaccines

Authors: J. Stephen | H. E. Scales | R. A. Benson | D. Erben | P. Garside | J. M. Brewer

Immunofocusing and enhancing autologous Tier-2 HIV-1 neutralization by displaying Env trimers on two-component protein nanoparticles

JOURNAL ARTICLE published 9 February 2021 in npj Vaccines

Research funded by Bill and Melinda Gates Foundation (OPP1132237,OPP1111923,INV-008352/OPP1153692,OPP1153692,OPP1132237) | EC | Horizon 2020 Framework Programme (681137,681137) | amfAR, The Foundation for AIDS Research (109514-61-RKVA) | U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases (P01 AI110657,AI144462)

Authors: Philip J. M. Brouwer | Aleksandar Antanasijevic | Marlon de Gast | Joel D. Allen | Tom P. L. Bijl | Anila Yasmeen | Rashmi Ravichandran | Judith A. Burger | Gabriel Ozorowski | Jonathan L. Torres | Celia LaBranche | David C. Montefiori | Rajesh P. Ringe | Marit J. van Gils | John P. Moore | Per Johan Klasse | Max Crispin | Neil P. King | Andrew B. Ward | Rogier W. Sanders

Sequential immunization induces strong and broad immunity against all four dengue virus serotypes

JOURNAL ARTICLE published 24 July 2020 in npj Vaccines

Authors: Jue Hou | Shubham Shrivastava | Hooi Linn Loo | Lan Hiong Wong | Eng Eong Ooi | Jianzhu Chen

A protective bivalent vaccine against Rift Valley fever and bluetongue

JOURNAL ARTICLE published 30 July 2020 in npj Vaccines

Authors: Eva Calvo-Pinilla | Alejandro Marín-López | Sandra Moreno | Gema Lorenzo | Sergio Utrilla-Trigo | Luis Jiménez-Cabello | Julio Benavides | Aitor Nogales | Rafael Blasco | Alejandro Brun | Javier Ortego

Safety and immunogenicity of an AS03-adjuvanted plant-based SARS-CoV-2 vaccine in Adults with and without Comorbidities

JOURNAL ARTICLE published 9 November 2022 in npj Vaccines

Authors: Nathalie Charland | Philipe Gobeil | Stéphane Pillet | Iohann Boulay | Annie Séguin | Alexander Makarkov | Gretchen Heizer | Kapil Bhutada | Asif Mahmood | Sonia Trépanier | Karen Hager | Julia Jiang-Wright | Judith Atkins | Pooja Saxena | Matthew P. Cheng | Donald C. Vinh | Philippe Boutet | François Roman | Robbert Van Der Most | Maria Angeles Ceregido | Marc Dionne | Guy Tellier | Jean-Sébastien Gauthier | Brandon Essink | Michael Libman | Jason Haffizulla | André Fréchette | Marc-André D’Aoust | Nathalie Landry | Brian J. Ward

Factors influencing long-term persistence of anti-HBs after hepatitis B vaccination

JOURNAL ARTICLE published 26 December 2022 in npj Vaccines

Authors: Marco Fonzo | Chiara Bertoncello | Andrea Trevisan

Evaluation of the immunogenicity of prime-boost vaccination with the replication-deficient viral vectored COVID-19 vaccine candidate ChAdOx1 nCoV-19

JOURNAL ARTICLE published 27 July 2020 in npj Vaccines

Research funded by RCUK | Biotechnology and Biological Sciences Research Council (BBS/E/I/00007031,BBS/E/I/00007034,BBS/E/I/00007037,BBS/E/I/00007039,BBS/E/I/00007031,BBS/E/I/00007034,BBS/E/I/00007037,BBS/E/I/00007039,BBS/E/I/00007031,BBS/E/I/00007034,BBS/E/I/00007037,BBS/E/I/00007039,BBS/E/I/00007031,BBS/E/I/00007034,BBS/E/I/00007037,BBS/E/I/00007039,BBS/E/I/00007031,BBS/E/I/00007034,BBS/E/I/00007037,BBS/E/I/00007039,BBS/E/I/00007031,BBS/E/I/00007034,BBS/E/I/00007037,BBS/E/I/00007039,BBS/E/I/00007031,BBS/E/I/00007034,BBS/E/I/00007037,BBS/E/I/00007039,BBS/E/I/00007031,BBS/E/I/00007034,BBS/E/I/00007037,BBS/E/I/00007039,BBS/E/I/00007031,BBS/E/I/00007034,BBS/E/I/00007037,BBS/E/I/00007039,BBS/E/I/00007031,BBS/E/I/00007034,BBS/E/I/00007037,BBS/E/I/00007039,BBS/E/I/00007031,BBS/E/I/00007034,BBS/E/I/00007037,BBS/E/I/00007039,BBS/E/I/00007031,BBS/E/I/00007034,BBS/E/I/00007037,BBS/E/I/00007039,BBS/E/I/00007031,BBS/E/I/00007034,BBS/E/I/00007037,BBS/E/I/00007039,BBS/E/I/00007031,BBS/E/I/00007034,BBS/E/I/00007037,BBS/E/I/00007039,BBS/E/I/00007031,BBS/E/I/00007034,BBS/E/I/00007037,BBS/E/I/00007039,BBS/E/I/00007031,BBS/E/I/00007034,BBS/E/I/00007037,BBS/E/I/00007039,BBS/E/I/00007031,BBS/E/I/00007034,BBS/E/I/00007037,BBS/E/I/00007039,BBS/E/I/00007031,BBS/E/I/00007034,BBS/E/I/00007037,BBS/E/I/00007039,BBS/E/I/00007031,BBS/E/I/00007034,BBS/E/I/00007037,BBS/E/I/00007039,BBS/E/I/00007031,BBS/E/I/00007034,BBS/E/I/00007037,BBS/E/I/00007039,BBS/E/I/00007031,BBS/E/I/00007034,BBS/E/I/00007037,BBS/E/I/00007039,BBS/E/I/00007031,BBS/E/I/00007034,BBS/E/I/00007037,BBS/E/I/00007039,BBS/E/I/00007031,BBS/E/I/00007034,BBS/E/I/00007037,BBS/E/I/00007039,BBS/E/I/00007031,BBS/E/I/00007034,BBS/E/I/00007037,BBS/E/I/00007039,BBS/E/I/00007031,BBS/E/I/00007034,BBS/E/I/00007037,BBS/E/I/00007039,BBS/E/I/00007031,BBS/E/I/00007034,BBS/E/I/00007037,BBS/E/I/00007039) | Bill and Melinda Gates Foundation (OPP1215550,OPP1215550,OPP1215550,OPP1215550,OPP1215550,OPP1215550,OPP1215550,OPP1215550,OPP1215550,OPP1215550,OPP1215550,OPP1215550,OPP1215550,OPP1215550,OPP1215550,OPP1215550,OPP1215550,OPP1215550,OPP1215550,OPP1215550,OPP1215550,OPP1215550,OPP1215550,OPP1215550,OPP1215550,OPP1215550) | RCUK | Engineering and Physical Sciences Research Council (EP/R013756/1,EP/R013756/1,EP/R013756/1,EP/R013756/1,EP/R013756/1,EP/R013756/1,EP/R013756/1,EP/R013756/1,EP/S025243/1,EP/S025243/1,EP/R013756/1,EP/R013756/1) | U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases (HHSN272201400008C,HHSN272201400008C,HHSN272201400008C,HHSN272201400008C,HHSN272201400008C,HHSN272201400008C,HHSN272201400008C,HHSN272201400008C,HHSN272201400008C,HHSN272201400008C)

Authors: Simon P. Graham | Rebecca K. McLean | Alexandra J. Spencer | Sandra Belij-Rammerstorfer | Daniel Wright | Marta Ulaszewska | Jane C. Edwards | Jack W. P. Hayes | Veronica Martini | Nazia Thakur | Carina Conceicao | Isabelle Dietrich | Holly Shelton | Ryan Waters | Anna Ludi | Ginette Wilsden | Clare Browning | Dagmara Bialy | Sushant Bhat | Phoebe Stevenson-Leggett | Philippa Hollinghurst | Ciaran Gilbride | David Pulido | Katy Moffat | Hannah Sharpe | Elizabeth Allen | Valerie Mioulet | Chris Chiu | Joseph Newman | Amin S. Asfor | Alison Burman | Sylvia Crossley | Jiandong Huo | Raymond J. Owens | Miles Carroll | John A. Hammond | Elma Tchilian | Dalan Bailey | Bryan Charleston | Sarah C. Gilbert | Tobias J. Tuthill | Teresa Lambe

Messenger RNA expressing PfCSP induces functional, protective immune responses against malaria in mice

JOURNAL ARTICLE published 18 June 2021 in npj Vaccines

Authors: Katherine L. Mallory | Justin A. Taylor | Xiaoyan Zou | Ishita N. Waghela | Cosette G. Schneider | Michael Q. Sibilo | Neeraja M. Punde | Leah C. Perazzo | Tatyana Savransky | Martha Sedegah | Sheetij Dutta | Chris J. Janse | Norbert Pardi | Paulo J. C. Lin | Ying K. Tam | Drew Weissman | Evelina Angov

Multicomponent gold nano-glycoconjugate as a highly immunogenic and protective platform against Burkholderia mallei

JOURNAL ARTICLE published 10 September 2020 in npj Vaccines

Research funded by U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases (AI12660101,AI12660101)

Authors: Daniel Tapia | Javier I. Sanchez-Villamil | Alfredo G. Torres

Vaccine genetics of IGHV1-2 VRC01-class broadly neutralizing antibody precursor naïve human B cells

JOURNAL ARTICLE published 6 September 2021 in npj Vaccines

Research funded by U.S. Department of Health & Human Services | National Institutes of Health (AI144462,AI144462,AI100663,AI142590,AI138963)

Authors: Jeong Hyun Lee | Laura Toy | Justin T. Kos | Yana Safonova | William R. Schief | Colin Havenar-Daughton | Corey T. Watson | Shane Crotty