Engineering precision therapies: lessons and motivations from the clinic

JOURNAL ARTICLE published 17 February 2021 in Synthetic Biology

Research funded by National Center of Competence in Research on Molecular Systems Engineering and in part by the European Research Council (785800)

Authors: Mingqi Xie | Mirta Viviani | Martin Fussenegger

Moving towards chemical-free agriculture, 37 kb at a time

JOURNAL ARTICLE published 17 February 2021 in Synthetic Biology

Authors: Sonja Billerbeck

OpenMTA, a paradigm shift in exchanging biological material

JOURNAL ARTICLE published 1 January 2018 in Synthetic Biology

Authors: Konstantinos Vavitsas

Construction of an artificial biosynthetic pathway for hyperextended archaeal membrane lipids in the bacteriumEscherichia coli

JOURNAL ARTICLE published 1 January 2020 in Synthetic Biology

Research funded by JSPS KAKENHI (18K19170,19H04651,20H02899) | Noda Institute for Scientific Research (19J21282)

Authors: Ryo Yoshida | Hisashi Hemmi

Engineering DNA nanotubes for resilience in an E. coli TXTL system

JOURNAL ARTICLE published 1 January 2018 in Synthetic Biology

Research funded by Office of Science (DE-SC0010595) | Human Frontier Science Program (RGP0037/2015)

Authors: Melissa A Klocke | Jonathan Garamella | Hari K K Subramanian | Vincent Noireaux | Elisa Franco

Highly efficient libraries design for saturation mutagenesis

JOURNAL ARTICLE published 2 February 2022 in Synthetic Biology

Research funded by Office of Science (DE-SC0018368)

Authors: Gur Pines | Assaf Pines | Carrie A Eckert

Advances in in vitro genetic code reprogramming in 2014–2017

JOURNAL ARTICLE published 1 January 2018 in Synthetic Biology

Research funded by Core Research for Evolutional Science and Technology (JPMJCR12L2) | Japan Society for the Promotion of Science (26220204) | Precursory Research for Embryonic Science and Technology (JPMJPR14K3)

Authors: Takayuki Katoh | Toby Passioura | Hiroaki Suga

Speaking to nature: a deep learning representational model of proteins ushers in protein linguistics

JOURNAL ARTICLE published 1 January 2019 in Synthetic Biology

Authors: Daniel Bojar

Harnessing synthetic biology to expand chemical diversity of antibiotics

JOURNAL ARTICLE published 17 February 2021 in Synthetic Biology

Authors: Fatima Enam

Editing Aspergillus terreus using the CRISPR-Cas9 system

JOURNAL ARTICLE published 28 December 2022 in Synthetic Biology

Research funded by Ministry of Science and Technology, Taiwan (MOST-108-2320-B-110-007-MY3)

Authors: Sra-Yh Shih | Uffe Hasbro Mortensen | Fang-Rong Chang | HsinYuan Tsai

Different protein localizations on the inner and outer leaflet of cell-sized liposomes using cell-free protein synthesis

JOURNAL ARTICLE published 1 January 2018 in Synthetic Biology

Authors: Atsuko Uyeda | Takayoshi Watanabe | Takahiro Hohsaka | Tomoaki Matsuura

High-yield ‘one-pot’ biosynthesis of raspberry ketone, a high-value fine chemical

JOURNAL ARTICLE published 26 October 2021 in Synthetic Biology

Research funded by Engineering and Physical Sciences Research Council (EP/K038648/1)

Authors: Simon J Moore | Tommaso Tosi | David Bell | Yonek B Hleba | Karen M Polizzi | Paul S Freemont

Investing in our nation’s future military leaders’ synthetic biology knowledge to understand and recognize threats and applications

JOURNAL ARTICLE published 1 January 2019 in Synthetic Biology

Authors: J Jordan Steel | Katherine L Bates | Michael D Barnhart

Engineering a living biomaterial via bacterial surface capture of environmental molecules

JOURNAL ARTICLE published 1 January 2018 in Synthetic Biology

Research funded by National Science Foundation (1709238) | Office of Naval Research (N00014-17-12306,N00014-15-1-2502) | Air Force Office of Scientific Research (FA9550-13-1-0108)

Authors: Felicia Y Scott | Keith C Heyde | MaryJoe K Rice | Warren C Ruder

Advances in engineering CRISPR-Cas9 as a molecular Swiss Army knife

JOURNAL ARTICLE published 1 January 2020 in Synthetic Biology

Research funded by BrisSynBio, a BBSRC/EPSRC Synthetic Biology Research Centre (BB/L01386X/1) | Royal Society University Research Fellowship (UF160357)

Authors: Grace A Meaker | Emma J Hair | Thomas E Gorochowski

Aquarium: open-source laboratory software for design, execution and data management

JOURNAL ARTICLE published 17 February 2021 in Synthetic Biology

Research funded by Defense Advanced Research Projects Agency (HR001117C0095)

Authors: Justin Vrana | Orlando de Lange | Yaoyu Yang | Garrett Newman | Ayesha Saleem | Abraham Miller | Cameron Cordray | Samer Halabiya | Michelle Parks | Eriberto Lopez | Sarah Goldberg | Benjamin Keller | Devin Strickland | Eric Klavins

Building a custom high-throughput platform at the Joint Genome Institute for DNA construct design and assembly—present and future challenges

JOURNAL ARTICLE published 1 January 2020 in Synthetic Biology

Research funded by U.S. Department of Energy, Office of Science, Office of Biological and Environmental Research (DE-AC02-05CH11231)

Authors: Ian K Blaby | Jan-Fang Cheng

Translation inhibition and resource balance in the TX-TL cell-free gene expression system

JOURNAL ARTICLE published 1 January 2017 in Synthetic Biology

Research funded by Office of Naval Research (ONR N00014-13-1-0074)

Authors: Vijayalakshmi H Nagaraj | James M Greene | Anirvan M Sengupta | Eduardo D Sontag

The naringenin-dependent regulator FdeR can be applied as a NIMPLY gate controlled by naringenin and arabinose

JOURNAL ARTICLE published 18 January 2024 in Synthetic Biology

Research funded by National Council for Scientific and Technological Development of the Ministry of Science and Technology of Brazil (313710/2018-0 446077/2020-8) | National Geographic Society (51118T-18) | National Council for Scientific and Technological Development of the Ministry of Science and Technology of Brazil (313710/2018-0 446077/2020-8) | National Geographic Society (51118T-18)

Authors: Fernanda Miyuki Kashiwagi | Brenno Wendler Miranda | Emanuel Maltempi de Souza | Marcelo Müller-Santos

Construction of a novel phagemid to produce custom DNA origami scaffolds

JOURNAL ARTICLE published 1 January 2018 in Synthetic Biology

Research funded by Army Research Office (W911NF-14-1-0507) | Del E. Webb Foundation (p13-2-28) | National Science Foundation (CCF-1317640) | Ruth L. Kirschstein NRSA Postdoctoral Fellowship (F32GM119322) | Burroughs Wellcome Fund (1010247)

Authors: Parsa M Nafisi | Tural Aksel | Shawn M Douglas