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Recurrent UBE3C-LRP5 translocations in head and neck cancer with therapeutic implications

JOURNAL ARTICLE published 4 March 2024 in npj Precision Oncology

Research funded by DBT India Alliance (IA/I/11/2500278)

Authors: Bhasker Dharavath | Ashwin Butle | Akshita Chaudhary | Ankita Pal | Sanket Desai | Aniket Chowdhury | Rahul Thorat | Pawan Upadhyay | Sudhir Nair | Amit Dutt

Author Correction: Circulating tumor cell heterogeneity in neuroendocrine prostate cancer by single cell copy number analysis

JOURNAL ARTICLE published 13 September 2021 in npj Precision Oncology

Authors: Vincenza Conteduca | Sheng-Yu Ku | Luisa Fernandez | Angel Dago-Rodriquez | Jerry Lee | Adam Jendrisak | Megan Slade | Cole Gilbertson | Jyothi Manohar | Michael Sigouros | Yipeng Wang | Ryan Dittamore | Rick Wenstrup | Juan Miguel Mosquera | Joseph D. Schonhoft | Himisha Beltran

Retraction Note: Birinapant sensitizes platinum-resistant carcinomas with high levels of cIAP to carboplatin therapy

JOURNAL ARTICLE published 9 August 2021 in npj Precision Oncology

Authors: V. La | R. Fujikawa | D. M. Janzen | M. Nunez | L. Bainvoll | L. Hwang | K. Faull | G. Lawson | S. Memarzadeh

Towards precision radiation oncology: endocrine therapy response as a biomarker for personalization of breast radiotherapy

JOURNAL ARTICLE published 24 January 2023 in npj Precision Oncology

Research funded by U.S. Department of Defense (W81XWH-21-1-0112,W81XWH-21-1-0114) | U.S. Department of Health & Human Services | National Institutes of Health (R01CA245294) | Cancer Prevention and Research Institute of Texas (RP190454)

Authors: S. M. Nashir Udden | GuemHee Baek | Kamal Pandey | Chantal Vidal | Yulun Liu | Asal S. Rahimi | D. Nathan Kim | Chika R. Nwachukwu | Ram S. Mani | Prasanna G. Alluri

RETRACTED ARTICLE: Birinapant sensitizes platinum-resistant carcinomas with high levels of cIAP to carboplatin therapy

JOURNAL ARTICLE published 3 April 2017 in npj Precision Oncology

Authors: V. La | R. Fujikawa | D. M. Janzen | M. Nunez | L. Bainvoll | L. Hwang | K. Faull | G. Lawson | S. Memarzadeh

Emergence of mTOR mutation as an acquired resistance mechanism to AKT inhibition, and subsequent response to mTORC1/2 inhibition

JOURNAL ARTICLE published 1 December 2021 in npj Precision Oncology

Authors: Niamh Coleman | Vivek Subbiah | Shubham Pant | Keyur Patel | Sinchita Roy-Chowdhuri | Sireesha Yedururi | Amber Johnson | Timothy A. Yap | Jordi Rodon | Kenna Shaw | Funda Meric-Bernstam

Biallelic EPCAM deletions induce tissue-specific DNA repair deficiency and cancer predisposition

JOURNAL ARTICLE published 11 March 2024 in npj Precision Oncology

Research funded by Gouvernement du Canada | Canadian Institutes of Health Research (PJT-156006) | Gouvernement du Canada | Instituts de Recherche en Santé du Canada | CIHR Skin Research Training Centre (MOP-137899) | EIF | Stand Up To Cancer (SU2C-AACR-CT01-17)

Authors: V. J. Forster | M. Aronson | C. Zhang | J. Chung | S. Sudhaman | M. A. Galati | J. Kelly | L. Negm | A. B. Ercan | L. Stengs | C. Durno | M. Edwards | M. Komosa | L. E. Oldfield | N. M. Nunes | S. Pedersen | J. Wellum | I. Siddiqui | V. Bianchi | B. R. Weil | V. L. Fox | T. J. Pugh | J. Kamihara | U. Tabori

Recent advances in precision oncology research

JOURNAL ARTICLE published 16 April 2018 in npj Precision Oncology

Authors: Ann M. Bode | Zigang Dong

Somatic copy number profiling from hepatocellular carcinoma circulating tumor cells

JOURNAL ARTICLE published 2 July 2020 in npj Precision Oncology

Authors: Colin M. Court | Shuang Hou | Lian Liu | Paul Winograd | Benjamin J. DiPardo | Sean X. Liu | Pin-Jung Chen | Yazhen Zhu | Matthew Smalley | Ryan Zhang | Saeed Sadeghi | Richard S. Finn | Fady M. Kaldas | Ronald W. Busuttil | Xianghong J. Zhou | Hsian-Rong Tseng | James S. Tomlinson | Thomas G. Graeber | Vatche G. Agopian

Case series of outcomes in advanced cancer patients with single pathway alterations receiving N-of-One therapies

JOURNAL ARTICLE published 28 March 2022 in npj Precision Oncology

Research funded by U.S. Department of Health & Human Services | NIH | NCI | Division of Cancer Epidemiology and Genetics, National Cancer Institute (Grants P30 CA023100) | U.S. Department of Health & Human Services | NIH | National Cancer Institute (K08CA168999 and R21CA192072)

Authors: Diviya Gupta | Razelle Kurzrock | Suzanna Lee | Ryosuke Okamura | Hyo Jeong Lim | Ki Hwan Kim | Jason K. Sicklick | Shumei Kato

Preoperative immune landscape predisposes adverse outcomes in hepatocellular carcinoma patients with liver transplantation

JOURNAL ARTICLE published 26 March 2021 in npj Precision Oncology

Research funded by National Research Foundation of Korea (2014M3C9A3063541,2018R1A2B2003782,2020R1A4A1018398,2020R1A6A3A13076391) | Ministry of Health and Welfare (HI15C3224)

Authors: Sang-Ho Yoon | Seo-Won Choi | Suk Woo Nam | Kyoung Bun Lee | Jin-Wu Nam

ELAVL2 loss promotes aggressive mesenchymal transition in glioblastoma

JOURNAL ARTICLE published 28 March 2024 in npj Precision Oncology

Research funded by National Research Foundation of Korea (2015M3C7A1028926 & 2020M3A9G8022029) | Korea Research Institute of Bioscience and Biotechnology (KGM456212109816) | Electronics and Telecommunications Research Institute (21YB1500)

Authors: Yona Kim | Ji Hyeon You | Yeonjoo Ryu | Gyuri Park | Urim Lee | Hyo Eun Moon | Hye Ran Park | Chang W. Song | Ja-Lok Ku | Sung-Hye Park | Sun Ha Paek

Artificial intelligence in neuro-oncology: advances and challenges in brain tumor diagnosis, prognosis, and precision treatment

JOURNAL ARTICLE published 29 March 2024 in npj Precision Oncology

Research funded by Emory University (00128909)

Authors: Sirvan Khalighi | Kartik Reddy | Abhishek Midya | Krunal Balvantbhai Pandav | Anant Madabhushi | Malak Abedalthagafi

Development and testing of a polygenic risk score for breast cancer aggressiveness

JOURNAL ARTICLE published 15 May 2023 in npj Precision Oncology

Research funded by U.S. Department of Health & Human Services | NIH | National Cancer Institute (K08 CA237829,U01 CA195565,R01 CA129059,R01 CA105274,U01 CA195565,U01 CA196406,P01 CA210961,K24 CA169004)

Authors: Yiwey Shieh | Jacquelyn Roger | Christina Yau | Denise M. Wolf | Gillian L. Hirst | Lamorna Brown Swigart | Scott Huntsman | Donglei Hu | Jovia L. Nierenberg | Pooja Middha | Rachel S. Heise | Yushu Shi | Linda Kachuri | Qianqian Zhu | Song Yao | Christine B. Ambrosone | Marilyn L. Kwan | Bette J. Caan | John S. Witte | Lawrence H. Kushi | Laura van ‘T Veer | Laura J. Esserman | Elad Ziv

Superhydrophobic lab-on-chip measures secretome protonation state and provides a personalized risk assessment of sporadic tumour

JOURNAL ARTICLE published 19 November 2018 in npj Precision Oncology

Authors: N. Malara | F. Gentile | N. Coppedè | M. L. Coluccio | P. Candeloro | G. Perozziello | L. Ferrara | M. Giannetto | M. Careri | A. Castellini | C. Mignogna | I. Presta | C. K. Pirrone | D. Maisano | A. Donato | G. Donato | M. Greco | D. Scumaci | G. Cuda | F. Casale | E. Ferraro | S. Bonacci | V. Trunzo | V. Mollace | V. Onesto | R. Majewska | F. Amato | M. Renne | N. Innaro | G. Sena | R. Sacco | F. Givigliano | C. Voci | G. Volpentesta | G. Guzzi | A. Lavano | E. Scali | U. Bottoni | E. Di Fabrizio

Multi-omics analysis reveals NNMT as a master metabolic regulator of metastasis in esophageal squamous cell carcinoma

JOURNAL ARTICLE published 30 January 2024 in npj Precision Oncology

Research funded by National Natural Science Foundation of China (82173386,92059203,82172982,82172992)

Authors: Qi Huang | Haiming Chen | Dandan Yin | Jie Wang | Shaodong Wang | Feng Yang | Jiawei Li | Teng Mu | Jilun Li | Jia Zhao | Rong Yin | Wei Li | Mantang Qiu | Erbao Zhang | Xiangnan Li

Tumor inherent interferon regulators as biomarkers of long-term chemotherapeutic response in TNBC

JOURNAL ARTICLE published 29 August 2019 in npj Precision Oncology

Authors: Natasha K. Brockwell | Jai Rautela | Katie L. Owen | Linden J. Gearing | Siddhartha Deb | Kate Harvey | Alex Spurling | Damien Zanker | Chia-Ling Chan | Helen E. Cumming | Niantao Deng | Jasmine M. Zakhour | Hendrika M. Duivenvoorden | Tina Robinson | Marion Harris | Michelle White | Jane Fox | Corinne Ooi | Beena Kumar | Jacqui Thomson | Nicole Potasz | Alex Swarbrick | Paul J. Hertzog | Tim J. Molloy | Sandra O’ Toole | Vinod Ganju | Belinda S. Parker

Tailored duration of adjuvant trastuzumab for human epidermal growth factor receptor 2-positive breast cancer

JOURNAL ARTICLE published 5 August 2020 in npj Precision Oncology

Research funded by National Natural Science Foundation of China (81672600 and 81722032)

Authors: Ke-Da Yu | Xin Wang | Wan-Kun Chen | Lei Fan | Miao Mo | Han Chen

A single nucleotide variant of human PARP1 determines response to PARP inhibitors

JOURNAL ARTICLE published 27 April 2020 in npj Precision Oncology

Authors: Rivki Cashman | Alona Zilberberg | Avner Priel | Hagit Philip | Alexander Varvak | Avi Jacob | Irit Shoval | Sol Efroni

Targeting extracellular and juxtamembrane FGFR2 mutations in chemotherapy-refractory cholangiocarcinoma

JOURNAL ARTICLE published 3 September 2021 in npj Precision Oncology

Authors: Michael Bitzer | Stephan Spahn | Sepideh Babaei | Marius Horger | Stephan Singer | Klaus Schulze-Osthoff | Pavlos Missios | Sergios Gatidis | Dominik Nann | Sven Mattern | Veit Scheble | Konstantin Nikolaou | Sorin Armeanu-Ebinger | Martin Schulze | Christopher Schroeder | Saskia Biskup | Janina Beha | Manfred Claassen | Kristina Ruhm | Antti Poso | Nisar P. Malek