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Assessing the subjective effects of stimulants in casual users; A methodology and preliminary results

JOURNAL ARTICLE published August 1978 in Clinical Pharmacology & Therapeutics

Authors: Jonathan O. Cole | Harrison G. Pope | Richard LaBrie | Martin Ionescu-Pioggia

Human pharmacology and abuse potential of meptazinol

JOURNAL ARTICLE published April 1987 in Clinical Pharmacology and Therapeutics

Authors: Rolley E Johnson | Donald R Jasinski

Methadone‐naloxone mixtures for use in methadone maintenance programs; I. An evaluation in man of their pharmacological feasibility; II. Demonstration of acute physical dependence

JOURNAL ARTICLE published February 1974 in Clinical Pharmacology & Therapeutics

Authors: John G. Nutt | Donald R. Jasinski

Oxaprozin disposition in renal disease

JOURNAL ARTICLE published April 1982 in Clinical Pharmacology and Therapeutics

Authors: Soong T Chiang | Gail Morrison | John A Knowles | Hans W Ruelius | Barry R Walker

Diazepam tapering in detoxification for high-dose benzodiazepine abuse

JOURNAL ARTICLE published October 1984 in Clinical Pharmacology and Therapeutics

Authors: M Harrison | U Busto | C A Naranjo | H L Kaplan | E M Sellers

Studies of delayed‐action medication

JOURNAL ARTICLE published January 1965 in Clinical Pharmacology & Therapeutics

Authors: Leo E. Hollister | Saul L. Kanter

Efficacy and Effectiveness Too Trials: Clinical Trial Designs to Generate Evidence on Efficacy and on Effectiveness in Wide Practice

JOURNAL ARTICLE published April 2019 in Clinical Pharmacology & Therapeutics

Research funded by National Institutes of Health (U24TR001609)

Authors: Harry P. Selker | Hans‐Georg Eichler | Norman L. Stockbridge | Newell E. McElwee | Willard H. Dere | Theodora Cohen | John K. Erban | Vicki L. Seyfert‐Margolis | Peter K. Honig | Kenneth I. Kaitin | Kenneth A. Oye | Ralph B. D'Agostino

Effect of CYP4F2,VKORC1, and CYP2C9 in Influencing Coumarin Dose: A Single‐Patient Data Meta‐Analysis in More Than 15,000 Individuals

JOURNAL ARTICLE published June 2019 in Clinical Pharmacology & Therapeutics

Research funded by British Heart Foundation (RG/14/5/30893)

Authors: Elisa Danese | Sara Raimondi | Martina Montagnana | Angela Tagetti | Taimour Langaee | Paola Borgiani | Cinzia Ciccacci | Antonio J. Carcas | Alberto M. Borobia | Hoi Y. Tong | Cristina Dávila‐Fajardo | Mariana Rodrigues Botton | Stephane Bourgeois | Panos Deloukas | Michael D. Caldwell | Jim K. Burmester | Richard L. Berg | Larisa H. Cavallari | Katarzyna Drozda | Min Huang | Li‐Zi Zhao | Han‐Jing Cen | Rocio Gonzalez‐Conejero | Vanessa Roldan | Yusuke Nakamura | Taisei Mushiroda | Inna Y. Gong | Richard B. Kim | Keita Hirai | Kunihiko Itoh | Carlos Isaza | Leonardo Beltrán | Enrique Jiménez‐Varo | Marisa Cañadas‐Garre | Alice Giontella | Marianne K. Kringen | Kari Bente Foss Haug | Hye Sun Gwak | Kyung Eun Lee | Pietro Minuz | Ming Ta Michael Lee | Steven A. Lubitz | Stuart Scott | Cristina Mazzaccara | Lucia Sacchetti | Ece Genç | Mahmut Özer | Anil Pathare | Rajagopal Krishnamoorthy | Andras Paldi | Virginie Siguret | Marie‐Anne Loriot | Vijay Kumar Kutala | Guilherme Suarez‐Kurtz | Jamila Perini | Josh C. Denny | Andrea H. Ramirez | Balraj Mittal | Saurabh Singh Rathore | Hersh Sagreiya | Russ Altman | Mohamed Hossam A. Shahin | Sherief I. Khalifa | Nita A. Limdi | Charles Rivers | Aditi Shendre | Chrisly Dillon | Ivet M. Suriapranata | Hong‐Hao Zhou | Sheng‐Lan Tan | Vacis Tatarunas | Vaiva Lesauskaite | Yumao Zhang | Anke H. Maitland‐van der Zee | Talitha I. Verhoef | Anthonius de Boer | Monica Taljaard | Carlo Federico Zambon | Vittorio Pengo | Jieying Eunice Zhang | Munir Pirmohamed | Julie A. Johnson | Cristiano Fava

Absorption of nicotine from small cigars

JOURNAL ARTICLE published February 1978 in Clinical Pharmacology & Therapeutics

Authors: Alan Armitage | Colin Dollery | Terry Houseman | Eva Kohner | Peter J. Lewis | David Turner

Reinforcer Pathology: The Behavioral Economics of Abuse Liability Testing

JOURNAL ARTICLE published February 2017 in Clinical Pharmacology & Therapeutics

Authors: WK Bickel | SE Snider | AJ Quisenberry | JS Stein

Genotype-dependent time course of lymphocyte β2-adrenergic receptor down-regulation

JOURNAL ARTICLE published September 2003 in Clinical Pharmacology & Therapeutics

Authors: H Bruck

Pharmacokinetics and pharmacodynamics of multiple oral doses of MK-0591, a 5-lipoxygenase—activating protein inhibitor

JOURNAL ARTICLE published July 1994 in Clinical Pharmacology and Therapeutics

Authors: Marken Depré | Beth Friedman | Anne Van Hecken | Inge De Lepeleire | Wesley Tanaka | Aimee Dallob | Sumiko Shingo | Arturo Porras | Charles Lin | Paul J De Schepper

Real‐World Rivaroxaban and Apixaban Levels in Asian Patients With Atrial Fibrillation

JOURNAL ARTICLE published January 2020 in Clinical Pharmacology & Therapeutics

Authors: Shin‐Yi Lin | Ching‐Hua Kuo | Shin‐Joe Yeh | Li‐Kai Tsai | Yen‐Bin Liu | Chih‐Fen Huang | Sung‐Chun Tang | Jiann‐Shing Jeng

Meperidine disposition in man: Influence of urinary pH and route of administration

JOURNAL ARTICLE published November 1981 in Clinical Pharmacology and Therapeutics

Authors: Roger K Verbeeck | Robert A Branch | Grant R Wilkinson

Combination Products Regulation at the FDA

JOURNAL ARTICLE published May 2009 in Clinical Pharmacology & Therapeutics

Authors: KJ Lauritsen | T Nguyen

Population Pharmacokinetics and Pharmacodynamics of Chloroquine in a Plasmodium vivax Volunteer Infection Study

JOURNAL ARTICLE published November 2020 in Clinical Pharmacology & Therapeutics

Authors: Azrin N. Abd‐Rahman | Louise Marquart | Nathalie Gobeau | Anne Kümmel | Julie A. Simpson | Stephan Chalon | Jörg J. Möhrle | James S. McCarthy

Polygenic Risk Score and Statin Relative Risk Reduction for Primary Prevention of Myocardial Infarction in a Real‐World Population

JOURNAL ARTICLE published November 2022 in Clinical Pharmacology & Therapeutics

Authors: Akinyemi Oni‐Orisan | Tanushree Haldar | Mari A.S. Cayabyab | Dilrini K. Ranatunga | Thomas J. Hoffmann | Carlos Iribarren | Ronald M. Krauss | Neil Risch

Considerations for Human ADME Strategy and Design Paradigm Shift(s) – An Industry White Paper

JOURNAL ARTICLE published April 2023 in Clinical Pharmacology & Therapeutics

Authors: Graeme C. Young | Douglas K. Spracklin | Alexander D. James | Mette G. Hvenegaard | Graeme Scarfe | David S. Wagner | Katrin Georgi | Hanno Schieferstein | Inga Bjornsdottir | Bianca van Groen | Andrea A. Romeo | Kenneth C. Cassidy | Georges Da‐violante | Bojan Bister | Stefan Blech | Ramaswamy Lyer | Simone I. Schulz | Filip Cuyckens | Patricia Moliner

Roadmap to 2030 for Drug Evaluation in Older Adults

JOURNAL ARTICLE published August 2022 in Clinical Pharmacology & Therapeutics

Authors: Qi Liu | Janice B. Schwartz | Patricia W. Slattum | S.W. Johnny Lau | Daphne Guinn | Rajanikanth Madabushi | Gilbert Burckart | Robert Califf | Francesca Cerreta | Carolyn Cho | Jack Cook | Jamie Gamerman | Paul Goldsmith | Piet H. van der Graaf | Jerry H. Gurwitz | Sebastian Haertter | Sarah Hilmer | Shiew‐Mei Huang | Sharon K. Inouye | Bindu Kanapuru | Munir Pirmohamed | Phil Posner | Barbara Radziszewska | H. Keipp Talbot | Robert Temple

Physiologically‐Based Pharmacokinetic Models as Enablers of Precision Dosing in Drug Development: Pivotal Role of the Human Mass Balance Study

JOURNAL ARTICLE published January 2021 in Clinical Pharmacology & Therapeutics

Authors: Karen Rowland Yeo | Karthik Venkatakrishnan