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Discovery of Novel Tricyclic Full Agonists for the G-Protein-Coupled Niacin Receptor 109A with Minimized Flushing in Rats JOURNAL ARTICLE published 23 April 2009 in Journal of Medicinal Chemistry |
Exploiting Protein Conformational Change to Optimize Adenosine-Derived Inhibitors of HSP70 JOURNAL ARTICLE published 26 May 2016 in Journal of Medicinal Chemistry Research funded by Cancer Research UK (C309/A11566,C309/A8274) |
In VivoAnti-Chagas Vinylthio-, Vinylsulfinyl-, and Vinylsulfonylbenzofuroxan Derivatives JOURNAL ARTICLE published 1 November 2007 in Journal of Medicinal Chemistry |
Synthesis and Structure−Activity Relationship Studies of 3,6-Diazabicyclo[3.2.0]heptanes as Novel α4β2 Nicotinic Acetylcholine Receptor Selective Agonists JOURNAL ARTICLE published 1 November 2007 in Journal of Medicinal Chemistry |
Activity of Sulfonium Bisphosphonates on Tumor Cell Lines JOURNAL ARTICLE published 1 November 2007 in Journal of Medicinal Chemistry |
Synthesis, Potency, and In Vivo Profiles of Quinoline Containing Histamine H3Receptor Inverse Agonists JOURNAL ARTICLE published 1 November 2007 in Journal of Medicinal Chemistry |
Antiarrhythmic Hit to Lead Refinement in a Dish Using Patient-Derived iPSC Cardiomyocytes JOURNAL ARTICLE published 13 May 2021 in Journal of Medicinal Chemistry Research funded by California Institute for Regenerative Medicine (TR4-06857) |
Design, Synthesis, and Multivariate Quantitative Structure−Activity Relationship of SalicylanilidesPotent Inhibitors of Type III Secretion inYersinia JOURNAL ARTICLE published 1 November 2007 in Journal of Medicinal Chemistry |
Structure−Activity Studies of Novel Cyanoguanidine ATP-Sensitive Potassium Channel Openers for the Treatment of Overactive Bladder JOURNAL ARTICLE published 1 November 2007 in Journal of Medicinal Chemistry |
Bifunctional and Unusual Amino Acid β- or γ-Ester Prodrugs of Nucleoside Analogues for Improved Affinity to ATB0,+ and Enhanced Metabolic Stability: An Application to Floxuridine JOURNAL ARTICLE published 8 October 2020 in Journal of Medicinal Chemistry Research funded by National Natural Science Foundation of China (81360485,81560577,81860630) | Natural Science Foundation of Jiangxi Province (20181BAB205087) | Key Project of Jiangxi (20192ACB70012) |
Syntheses and Biological Activities (Topoisomerase Inhibition and Antitumor and Antimicrobial Properties) of Rebeccamycin Analogues Bearing Modified Sugar Moieties and Substituted on the Imide Nitrogen with a Methyl Group JOURNAL ARTICLE published 1 October 1997 in Journal of Medicinal Chemistry |
Synthesis and Antitumor Activities of Novel 6-5 Fused Ring Heterocycle Antifolates: N-[4-[.omega.-(2-Amino-4-substituted-6,7-dihydrocyclopenta[d]pyrimidin-5-yl)alkyl]benzoyl]-L-glutamic Acids JOURNAL ARTICLE published May 1994 in Journal of Medicinal Chemistry |
Development of a Small Hybrid Molecule That Mediates Degradation of His-Tag Fused Proteins JOURNAL ARTICLE published 25 January 2018 in Journal of Medicinal Chemistry Research funded by Japan Society for the Promotion of Science (16H05090,16K15121,26460169) |
Kinase-likeness and Kinase-Privileged Fragments: Toward Virtual Polypharmacology JOURNAL ARTICLE published 13 March 2008 in Journal of Medicinal Chemistry |
Preventive Oral Treatment with Resveratrol Pro-prodrugs Drastically Reduce Colon Inflammation in Rodents JOURNAL ARTICLE published 28 October 2010 in Journal of Medicinal Chemistry |
Design, Synthesis, and Biological Evaluation of Monopyrrolinone-Based HIV-1 Protease Inhibitors JOURNAL ARTICLE published 1 May 2003 in Journal of Medicinal Chemistry |
Development of Novel Aminoglycoside (NB54) with Reduced Toxicity and Enhanced Suppression of Disease-Causing Premature Stop Mutations JOURNAL ARTICLE published 14 May 2009 in Journal of Medicinal Chemistry |
Design, Synthesis, and Antiviral Activity of Certain 2,5,6-Trihalo-1-(.beta.-D-ribofuranosyl)benzimidazoles JOURNAL ARTICLE published September 1995 in Journal of Medicinal Chemistry |
Synthesis and Anticancer Activity of Brefeldin A Ester Derivatives JOURNAL ARTICLE published 1 June 2006 in Journal of Medicinal Chemistry |
Structure−Activity Relationships of New 1H-Imidazo[4,5-c]quinolin-4-amine Derivatives as Allosteric Enhancers of the A3 Adenosine Receptor JOURNAL ARTICLE published 1 June 2006 in Journal of Medicinal Chemistry |