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Synthesis and Optimization of a New Family of Type 3 17β-Hydroxysteroid Dehydrogenase Inhibitors by Parallel Liquid-Phase Chemistry

JOURNAL ARTICLE published 1 January 2002 in Journal of Medicinal Chemistry

Authors: René Maltais | Van Luu-The | Donald Poirier

https://doi.org/10.1021/jm010286y Actions

Corrections to Rational Modification of a Candidate Cancer Drug for Use against Chagas Disease

JOURNAL ARTICLE published 23 July 2009 in Journal of Medicinal Chemistry

Authors: James M. Kraus | Christophe L. M. J. Verlinde | Mandana Karimi | Galina I. Lepesheva | Michael H. Gelb | Frederick S. Buckner

https://doi.org/10.1021/jm900650s Actions

Structure Based Development of Phenylimidazole-Derived Inhibitors of Indoleamine 2,3-Dioxygenase

JOURNAL ARTICLE published 1 August 2008 in Journal of Medicinal Chemistry

Authors: Sanjeev Kumar | Daniel Jaller | Bhumika Patel | Judith M. LaLonde | James B. DuHadaway | William P. Malachowski | George C. Prendergast | Alexander J. Muller

https://doi.org/10.1021/jm800512z Actions

New Anticancer Agents Mimicking Protein Recognition Motifs

JOURNAL ARTICLE published 12 September 2013 in Journal of Medicinal Chemistry

Authors: Marco Persico | Anna Ramunno | Vita Maglio | Silvia Franceschelli | Chiara Esposito | Alfonso Carotenuto | Diego Brancaccio | Valeria De Pasquale | Luigi Michele Pavone | Michela Varra | Nausicaa Orteca | Ettore Novellino | Caterina Fattorusso

https://doi.org/10.1021/jm400947b Actions

Synthesis of two metabolites of (+)-propoxyphene

JOURNAL ARTICLE published August 1977 in Journal of Medicinal Chemistry

Authors: William W. Turner | Richard N. Booher | Stephen E. Smits | Albert Pohland

https://doi.org/10.1021/jm00218a015 Actions

Miliusanes, A Class of Cytotoxic Agents from Miliusa sinensis

JOURNAL ARTICLE published 1 January 2006 in Journal of Medicinal Chemistry

Authors: Hong-Jie Zhang | Cuiying Ma | Nguyen Van Hung | Nguyen Manh Cuong | Ghee Teng Tan | Bernard D. Santarsiero | Andrew D. Mesecar | D. Doel Soejarto | John M. Pezzuto | Harry H. S. Fong

https://doi.org/10.1021/jm0509492 Actions

Acridine-Based Agents with Topoisomerase II Activity Inhibit Pancreatic Cancer Cell Proliferation and Induce Apoptosis

JOURNAL ARTICLE published 1 January 2008 in Journal of Medicinal Chemistry

Authors: John R. Goodell | Andrei V. Ougolkov | Hiroshi Hiasa | Harneet Kaur | Rory Remmel | Daniel D. Billadeau | David M. Ferguson

https://doi.org/10.1021/jm701228e Actions

Targeting Carnitine Biosynthesis: Discovery of New Inhibitors against γ-Butyrobetaine Hydroxylase

JOURNAL ARTICLE published 27 March 2014 in Journal of Medicinal Chemistry

Authors: Kaspars Tars | Janis Leitans | Andris Kazaks | Diana Zelencova | Edgars Liepinsh | Janis Kuka | Marina Makrecka | Daina Lola | Viktors Andrianovs | Daina Gustina | Solveiga Grinberga | Edvards Liepinsh | Ivars Kalvinsh | Maija Dambrova | Einars Loza | Osvalds Pugovics

https://doi.org/10.1021/jm401603e Actions

Structure−Selectivity Investigations of D2-Like Receptor Ligands by CoMFA and CoMSIA Guiding the Discovery of D3Selective PET Radioligands

JOURNAL ARTICLE published 8 February 2007 in Journal of Medicinal Chemistry

Authors: Ismail Salama | Carsten Hocke | Wolfgang Utz | Olaf Prante | Frank Boeckler | Harald Hübner | Torsten Kuwert | Peter Gmeiner

https://doi.org/10.1021/jm0611152 Actions

2,6,8-Trisubstituted 1-Deazapurines as Adenosine Receptor Antagonists

JOURNAL ARTICLE published 1 February 2007 in Journal of Medicinal Chemistry

Authors: Lisa C. W. Chang | Jacobien K. von Frijtag Drabbe Künzel | Thea Mulder-Krieger | Joost Westerhout | Thomas Spangenberg | Johannes Brussee | Adriaan P. IJzerman

https://doi.org/10.1021/jm0607956 Actions

Design, Synthesis, Structure−Selectivity Relationship, and Effect on Human Cancer Cells of a Novel Series of Histone Deacetylase 6-Selective Inhibitors

JOURNAL ARTICLE published 1 November 2007 in Journal of Medicinal Chemistry

Authors: Yukihiro Itoh | Takayoshi Suzuki | Akiyasu Kouketsu | Nobuaki Suzuki | Satoko Maeda | Minoru Yoshida | Hidehiko Nakagawa | Naoki Miyata

https://doi.org/10.1021/jm7009217 Actions

Modeling, Chemistry, and Biology of the Benzolactam Analogues of Indolactam V (ILV). 2. Identification of the Binding Site of the Benzolactams in the CRD2 Activator-Binding Domain of PKCδ and Discovery of an ILV Analogue of Improved Isozyme Selectivity

JOURNAL ARTICLE published 1 April 1997 in Journal of Medicinal Chemistry

Authors: Alan P. Kozikowski | Shaomeng Wang | Dawei Ma | Jiangchao Yao | Shakeel Ahmad | Robert I. Glazer | Krisztina Bogi | Peter Acs | Shayan Modarres | Nancy E. Lewin | Peter M. Blumberg

https://doi.org/10.1021/jm960875h Actions

Receptor Surface Models. 1. Definition and Construction

JOURNAL ARTICLE published June 1995 in Journal of Medicinal Chemistry

Authors: Mathew Hahn

https://doi.org/10.1021/jm00012a007 Actions

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JOURNAL ARTICLE published 1 July 1960 in Journal of Medicinal Chemistry

https://doi.org/10.1021/jm50011a902 Actions

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JOURNAL ARTICLE published 1 February 1961 in Journal of Medicinal Chemistry

https://doi.org/10.1021/jm50014a908 Actions

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JOURNAL ARTICLE published 1 April 1961 in Journal of Medicinal Chemistry

https://doi.org/10.1021/jm50015a903 Actions

Discovery of Orally Bioavailable 1,3,4-Trisubstituted 2-Oxopiperazine-Based Melanocortin-4 Receptor Agonists as Potential Antiobesity Agents

JOURNAL ARTICLE published 9 October 2008 in Journal of Medicinal Chemistry

Authors: Xinrong Tian | Adrian G. Switzer | Steve A. Derose | Rajesh K. Mishra | Mark G. Solinsky | Rashid N. Mumin | Frank H. Ebetino | Lalith R. Jayasinghe | Mark E. Webster | Anny-Odile Colson | Doreen Crossdoersen | Beth B. Pinney | Julie A. Farmer | Martin E. Dowty | Cindy M. Obringer | Charles A. Cruze | Melissa L. Burklow | Paula M. Suchanek | Lily Dong | Mary Kay Dirr | Russell J. Sheldon | John A. Wos

https://doi.org/10.1021/jm800525p Actions

Narcotic antagonists. 4. Carbon-6 derivatives of N-substituted noroxymorphones as narcotic antagonists

JOURNAL ARTICLE published March 1975 in Journal of Medicinal Chemistry

Authors: Elliot F. Hahn | Jack Fishman | Richard D. Heilman

https://doi.org/10.1021/jm00237a008 Actions

Novel Bis(1H-indol-2-yl)methanones as Potent Inhibitors of FLT3 and Platelet-Derived Growth Factor Receptor Tyrosine Kinase

JOURNAL ARTICLE published 1 June 2006 in Journal of Medicinal Chemistry

Authors: Siavosh Mahboobi | Andrea Uecker | Andreas Sellmer | Christophe Cénac | Heymo Höcher | Herwig Pongratz | Emerich Eichhorn | Harald Hufsky | Antje Trümpler | Marit Sicker | Florian Heidel | Thomas Fischer | Carol Stocking | Sigurd Elz | Frank-D. Böhmer | Stefan Dove

https://doi.org/10.1021/jm058033i Actions

(+)-cis-N-(para-, meta-, and ortho-substituted benzyl)-N-normetazocines: Synthesis and binding affinity at the [3H]-(+)-pentazocine-labeled (.sigma.1) site and quantitative structure-affinity relationship studies

JOURNAL ARTICLE published February 1995 in Journal of Medicinal Chemistry

Authors: S. Wayne Mascarella | Xu Bai | Wanda Williams | Bethel Sine | Wayne D. Bowen | F. Ivy Carroll

https://doi.org/10.1021/jm00003a019 Actions
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