A Calcineurin-Independent Mechanism of Angiogenesis Inhibition by a Nonimmunosuppressive Cyclosporin A Analog

JOURNAL ARTICLE published August 2011 in Journal of Pharmacology and Experimental Therapeutics

Authors: Benjamin A. Nacev | Woon-Kai Low | Zhennian Huang | Tina T. Su | Zhuang Su | Hisham Alkuraya | Dan Kasuga | Woong Sun | Mario Träger | Manfred Braun | Gunter Fischer | Kang Zhang | Jun O. Liu

Novel Phosphoinositide 3-Kinaseδ,γInhibitor: Potent Anti-Inflammatory Effects and Joint Protection in Models of Rheumatoid Arthritis

JOURNAL ARTICLE published February 2014 in Journal of Pharmacology and Experimental Therapeutics

Authors: David L. Boyle | Hae-Rim Kim | Katharyn Topolewski | Beatrix Bartok | Gary S. Firestein

Berberine Upregulates P-Glycoprotein in Human Caco-2 Cells and in an Experimental Model of Colitis in the Rat via Activation of Nrf2-Dependent Mechanisms

JOURNAL ARTICLE published August 2018 in Journal of Pharmacology and Experimental Therapeutics

Authors: Wanghui Jing | Yasaman Safarpour | Ting Zhang | Pengqi Guo | Guoning Chen | Xiaoming Wu | Qiang Fu | Yitao Wang

Radiosensitizing Effect of Novel Phenylpyrimidine Derivatives on Human Lung Cancer Cells via Cell Cycle Perturbation

JOURNAL ARTICLE published September 2019 in Journal of Pharmacology and Experimental Therapeutics

Authors: Seung-Youn Jung | Ky-Youb Nam | Jeong-In Park | Kyung-Hee Song | Jiyeon Ahn | Jong Kuk Park | Hong-Duck Um | Sang-Gu Hwang | Sang Un Choi | Jie-Young Song

E6201, a Novel Kinase Inhibitor of Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase-1 and Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase Kinase-1: In Vivo Effects on Cutaneous Inflammatory Responses by Topical Administration

JOURNAL ARTICLE published October 2010 in Journal of Pharmacology and Experimental Therapeutics

Authors: Kenzo Muramoto | Masaki Goto | Yoko Inoue | Naoto Ishii | Ken-ichi Chiba | Yoshikazu Kuboi | Takao Omae | Yuan J. Wang | Fabian Gusovsky | Hiroshi Shirota

Gastric Tolerability and Prolonged Prostaglandin Inhibition in the Brain with a Nitric Oxide-Releasing Flurbiprofen Derivative, NCX-2216 [3-[4-(2-Fluoro-α-methyl-[1,1′-biphenyl]-4-acetyloxy)-3-methoxyphenyl]-2-propenoic acid 4-nitrooxy butyl ester]

JOURNAL ARTICLE published May 2004 in Journal of Pharmacology and Experimental Therapeutics

Authors: John L. Wallace | Marcelo N. Muscará | Gilberto de Nucci | Stella Zamuner | Giuseppe Cirino | Piero del Soldato | Ennio Ongini

Brain Cholesterol Synthesis in Mice Is Affected by High Dose of Simvastatin but Not of Pravastatin

JOURNAL ARTICLE published March 2006 in Journal of Pharmacology and Experimental Therapeutics

Authors: Karin M. Thelen | Katharina M. Rentsch | Ursula Gutteck | Maura Heverin | Maria Olin | Ulla Andersson | Arnold von Eckardstein | Ingemar Björkhem | Dieter Lütjohann

Declines in Different β2* Nicotinic Receptor Populations in Monkey Striatum after Nigrostriatal Damage

JOURNAL ARTICLE published 1 November 2002 in Journal of Pharmacology and Experimental Therapeutics

Authors: Jennifer M. Kulak | John L. Musachio | J. Michael McIntosh | Maryka Quik

Pharmacological Characterization of the Nociceptin/Orphanin FQ Receptor Antagonist SB-612111 [(–)-cis-1-Methyl-7-[[4-(2,6-dichlorophenyl)piperidin-1-yl]methyl]-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-ol]: In Vitro Studies

JOURNAL ARTICLE published June 2007 in Journal of Pharmacology and Experimental Therapeutics

Authors: Barbara Spagnolo | Giacomo Carrà | Martina Fantin | Carmela Fischetti | Chris Hebbes | John McDonald | Timothy A. Barnes | Anna Rizzi | Claudio Trapella | Giulia Fanton | Michele Morari | Dave G. Lambert | Domenico Regoli | Girolamo Calò

Contribution of α₁GABA_Aand α₅GABA_AReceptor Subtypes to the Discriminative Stimulus Effects of Ethanol in Squirrel Monkeys

JOURNAL ARTICLE published May 2005 in Journal of Pharmacology and Experimental Therapeutics

Authors: Donna M. Platt | Annemarie Duggan | Roger D. Spealman | James M. Cook | Xiaoyan Li | Wenyuan Yin | James K. Rowlett

Aldehyde Dehydrogenase Type 2 Activation by Adenosine and Histamine Inhibits Ischemic Norepinephrine Release in Cardiac Sympathetic Neurons: Mediation by Protein Kinase Cε

JOURNAL ARTICLE published October 2012 in Journal of Pharmacology and Experimental Therapeutics

Authors: Pablo A. Robador | Nahid Seyedi | Noel Yan-Ki Chan | Kenichiro Koda | Roberto Levi

Protein-Based Nanocarriers and Nanotherapeutics for Infection and Inflammation

JOURNAL ARTICLE published January 2024 in Journal of Pharmacology and Experimental Therapeutics

Authors: Nupur Nagar | Goutami Naidu | Amit Mishra | Krishna Mohan Poluri

Prolonged Attenuation of Amygdala-Kindled Seizure Measures in Rats by Convection-Enhanced Delivery of the N-Type Calcium Channel Antagonists ω-Conotoxin GVIA and ω-Conotoxin MVIIA

JOURNAL ARTICLE published November 2007 in Journal of Pharmacology and Experimental Therapeutics

Authors: Maciej Gasior | Natalie A. White | Michael A. Rogawski

Hypoxia-Inducible Factor-1-Dependent and -Independent Regulation of Insulin-Like Growth Factor-1-Stimulated Vascular Endothelial Growth Factor Secretion

JOURNAL ARTICLE published August 2006 in Journal of Pharmacology and Experimental Therapeutics

Authors: Mark G. Slomiany | Steven A. Rosenzweig

Improved Left Ventricular Function and Reduced Necrosis after Myocardial Ischemia/Reperfusion in Rabbits Treated with Ranolazine, an Inhibitor of the Late Sodium Channel

JOURNAL ARTICLE published July 2006 in Journal of Pharmacology and Experimental Therapeutics

Authors: Sharon L. Hale | Justin A. Leeka | Robert A. Kloner

p38α-Selective Mitogen-Activated Protein Kinase Inhibitor SD-282 Reduces Inflammation in a Subchronic Model of Tobacco Smoke-Induced Airway Inflammation

JOURNAL ARTICLE published March 2008 in Journal of Pharmacology and Experimental Therapeutics

Authors: Satyanarayana Medicherla | Mary F. Fitzgerald | Dianne Spicer | Paul Woodman | Jing Y. Ma | Ann M. Kapoun | Sarvajit Chakravarty | Sundeep Dugar | Andrew A. Protter | Linda S. Higgins

Delivery of Galanin-Like Peptide to the Brain: Targeting with Intranasal Delivery and Cyclodextrins

JOURNAL ARTICLE published May 2008 in Journal of Pharmacology and Experimental Therapeutics

Authors: Naoko Nonaka | Susan A. Farr | Haruaki Kageyama | Seiji Shioda | William A. Banks

Lysosomal Biogenesis and Implications for Hydroxychloroquine Disposition

JOURNAL ARTICLE published February 2021 in Journal of Pharmacology and Experimental Therapeutics

Authors: Keagan P. Collins | Sandra Witta | Jonathan W. Coy | Yi Pang | Daniel L. Gustafson

Activation of G-Proteins by Morphine and Codeine Congeners: Insights to the Relevance of O- and N-Demethylated Metabolites at μ- and δ-Opioid Receptors

JOURNAL ARTICLE published February 2004 in Journal of Pharmacology and Experimental Therapeutics

Authors: Chad M. Thompson | Heidi Wojno | Elisabeth Greiner | Everette L. May | Kenner C. Rice | Dana E. Selley

Discriminative Stimulus Effects of 1-(2,5-Dimethoxy-4-methylphenyl)-2-aminopropane in Rhesus Monkeys

JOURNAL ARTICLE published February 2008 in Journal of Pharmacology and Experimental Therapeutics

Authors: Jun-Xu Li | Kenner C. Rice | Charles P. France