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Fungal transformations of antihistamines: metabolism of brompheniramine, chlorpheniramine, and pheniramine toN-oxide andN-demethylated metabolites by the fungusCunninghamella elegans

JOURNAL ARTICLE published January 1995 in Xenobiotica

Authors: E. B. Hansen | B. P. Cho | W. A. Korfmacher | Carl E. Cerniglia

Osthole inhibited the activity of CYP2C9 in human liver microsomes and influenced indomethacin pharmacokinetics in rats

JOURNAL ARTICLE published 2 August 2020 in Xenobiotica

Authors: Hui He | Yuandong Zhang | Dezhang Zhao | Junhao Jiang | Baogang Xie | Limei Ma | Xueqing Liu | Chao Yu

AmineDB: Large scale docking of amines with CYP2D6 and scoring for druglike properties—towards defining the scope of the chemical defense against foreign amines in humans

JOURNAL ARTICLE published March 2007 in Xenobiotica

Authors: A. D. Costache | D. Trawick | D. Bohl | D. S. Sem

Metabolism and excretion of loratadine in male and female mice, rats and monkeys

JOURNAL ARTICLE published February 2005 in Xenobiotica

Authors: R Ramanathan | N Alvarez | A.-D Su | S Chowdhury | K Alton | K Stauber | J Patrick

Investigation of the pharmacokinetics and metabolic fate of Fasiglifam (TAK-875) in male and female rats following oral and intravenous administration

JOURNAL ARTICLE published 1 February 2023 in Xenobiotica

Authors: Billy J. Molloy | Adam King | Lee A. Gethings | Robert S. Plumb | Russell J. Mortishire-Smith | Ian D. Wilson

Ethanol induced induction of cytochrome P450 2E1 and activation of mitogen activated protein kinases in peripheral blood lymphocytes

JOURNAL ARTICLE published April 2012 in Xenobiotica

Authors: Amit Sharma | Kumar Saurabh | Sanjay Yadav | Swatantra K. Jain | Devendra Parmar

Book Reviews

JOURNAL ARTICLE published January 1974 in Xenobiotica

Intracellular activation of 4-hydroxycyclophosphamide into a DNA-alkylating agent in human leucocytes

JOURNAL ARTICLE published 3 October 2021 in Xenobiotica

Authors: Minghan Yong | Kathryn Elisa Burns | Janak de Zoysa | Nuala Ann Helsby

Absorption, distribution, metabolism and excretion of telmesteine, amucolitic agent, in rat

JOURNAL ARTICLE published July 2003 in Xenobiotica

Authors: J. Lee | J. Son | S. W. Rhee | D. H. Kim

Aspirin acetylates the tricyclic antidepressant amoxapine spontaneously toN-acetylamoxapinein vitroandin vivo

JOURNAL ARTICLE published January 1990 in Xenobiotica

Authors: R. Middleberg | F. Rieders | J. J. Kocsis

Sodium tanshinone IIA sulfonate and its interactions with human CYP450s

JOURNAL ARTICLE published 1 December 2016 in Xenobiotica

Authors: D. Chen | X.-X. Lin | W.-H. Huang | W. Zhang | Z.-R. Tan | J.-B. Peng | Y.-C. Wang | Y. Guo | D.-L. Hu | Y. Chen

Re-evaluation of the role of P-glycoprotein inin vitrodrug permeability studies with the bovine brain microvessel endothelial cells

JOURNAL ARTICLE published March 2014 in Xenobiotica

Authors: Jenni J. Hakkarainen | Kirsi Rilla | Marjukka Suhonen | Marika Ruponen | Markus M. Forsberg

Influence of sodium benzoate on the metabolism ofo-xylene in the rat

JOURNAL ARTICLE published May 2005 in Xenobiotica

Authors: H. Moriwaki | Y. Tsujimoto | M. Shimizu | T. Noda | M. Warashina | M. Tanaka

Oral pharmacokinetic interaction of ester rich fruit juices and pharmaceutical excipients with tenofovir disoproxil fumarate in male Wistar rats

JOURNAL ARTICLE published 2 December 2017 in Xenobiotica

Authors: Joseph Shailender | Punna Rao Ravi | Paramita Saha | Srividya Myneni

Structure-activity relationship of atorvastatin derivatives for metabolic activation by hydrolases

JOURNAL ARTICLE published 3 March 2020 in Xenobiotica

Research funded by JSPS KAKENHI (9,8)

Authors: Kenta Mizoi | Masato Takahashi | Sachiko Sakai | Takuo Ogihara | Masami Haba | Masakiyo Hosokawa

The common indoor air pollutant α-pinene is metabolised to a genotoxic metabolite α-pinene oxide

JOURNAL ARTICLE published 4 March 2022 in Xenobiotica

Authors: Suramya Waidyanatha | Sherry R. Black | Kristine L. Witt | Timothy R. Fennell | Carol Swartz | Leslie Recio | Scott L. Watson | Purvi Patel | Reshan A. Fernando | Cynthia V. Rider

Cytochrome P450 2W1 (CYP2W1) – ready for use as the biomarker and drug target for cancer?

JOURNAL ARTICLE published 3 October 2017 in Xenobiotica

Authors: Yan Pan | Eng Chin Ong

Bioavailability and toxicological potential of wheat-bound pirimiphos-methyl residues in rats

JOURNAL ARTICLE published January 1992 in Xenobiotica

Authors: M. T. Akay | G. Yilmazoglu | S. Yašacan | H. Turk | D. Kolanyaka

Utility of preclinical species for uncertainty assessment and correction of prediction of human volume of distribution using the Rodgers-Lukacova model

JOURNAL ARTICLE published 3 July 2022 in Xenobiotica

Authors: Eva Sherbetjian | Sheila-Annie Peters | Carl Petersson

The permeability characteristics and interaction of the main components from Zhizi Bopi decoction in the MDCK cell model

JOURNAL ARTICLE published 2 August 2016 in Xenobiotica

Authors: Zhengyue Qian | Cheng Huang | Chenlin Shen | Xiaoming Meng | Zhaolin Chen | Tingting Hu | Yangyang Li | Jun Li