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Reduced Activity of Sphingosine-1-Phosphate Lyase Induces Podocyte-related Glomerular Proteinuria, Skin Irritation, and Platelet Activation

JOURNAL ARTICLE published July 2015 in Toxicologic Pathology

Authors: Jens Schümann | Armelle Grevot | David Ledieu | Armin Wolf | Anna Schubart | Alessandro Piaia | Esther Sutter | Serge Côté | Christian Beerli | François Pognan | Andreas Billich | Pierre Moulin | Ursula Junker Walker

Regulatory Forum Review*: Utility of in Vitro Secondary Pharmacology Data to Assess Risk of Drug-induced Valvular Heart Disease in Humans: Regulatory Considerations

JOURNAL ARTICLE published April 2017 in Toxicologic Pathology

Authors: Thomas Papoian | Gowraganahalli Jagadeesh | Muriel Saulnier | Natalie Simpson | Arippa Ravindran | Baichun Yang | Adebayo A. Laniyonu | Imran Khan | Ana Szarfman

Book Review: Toxicologic Pathology: Nonclinical Safety Assessment

JOURNAL ARTICLE published July 2015 in Toxicologic Pathology

Authors: Sabine Francke

Histological Features of Postnatal Development of the Eye in White Rabbits

JOURNAL ARTICLE published April 2021 in Toxicologic Pathology

Authors: Yoshinori Yamagiwa | Masaaki Kurata | Hiroshi Satoh

Nonclinical Safety Assessment of FHTR2163, An Antigen-Binding Fragment Against HTRA1 for the Treatment of Geographic Atrophy

JOURNAL ARTICLE published April 2021 in Toxicologic Pathology

Authors: Edward Dere | Susan Crowell | Mauricio Maia | Chris Schuetz | Phillip Lai | Vladimir Bantseev | Helen Booler

Spontaneous Acute Tumor Lysis Syndrome in a DBA/1J Mouse: A Case Report and Review

JOURNAL ARTICLE published August 2003 in Toxicologic Pathology

Authors: Karen Lovelace | Yvonne Vangessel | Ludmila V. Asher | Peter Vogel

TGFα is Dispensable for Skin Tumorigenesis in Tg.AC Mice

JOURNAL ARTICLE published July 1998 in Toxicologic Pathology

Authors: Michael C. Humble | Carl J. Szczesniak | Noreen C. Luetteke | Judson W. Spalding | Ronald E. Cannon | Laura A. Hansen | David C. Lee | Raymond W. Tennant

Review Article: Aberrant Crypt Foci: A Review

JOURNAL ARTICLE published November 1999 in Toxicologic Pathology

Authors: Cecilia M. Fenoglio-Preiser | Amy Noffsinger

A Perspective on Current and Future Uses of Alternative Models for Carcinogenicity Testing

JOURNAL ARTICLE published January 2001 in Toxicologic Pathology

Authors: Jay I. Goodman

Vascular Origin of Vildagliptin-induced Skin Effects in Cynomolgus Monkeys

JOURNAL ARTICLE published June 2014 in Toxicologic Pathology

Authors: Peter Hoffmann | Phil Bentley | Pritam Sahota | Heidi Schoenfeld | Lori Martin | Linda Longo | Robert Spaet | Pierre Moulin | Serafino Pantano | Valerie Dubost | Dan Lapadula | Bryan Burkey | Virendar Kaushik | Wei Zhou | Michael Hayes | Nick Flavahan | Salah-Dine Chibout | Steve Busch

Incidences and Range of Spontaneous Microscopic Lesions in the Eye of Sprague-Dawley Rats and Han Wistar Rats Used in Toxicity Studies

JOURNAL ARTICLE published April 2021 in Toxicologic Pathology

Authors: Emilie Cloup | Pedro Romao | Ian Taylor | Vasanthi Mowat | Sydney Mukaratirwa

Incidences of Selected Lesions in Control Female Harlan Sprague–Dawley Rats from Two-Year Studies Performed by the National Toxicology Program

JOURNAL ARTICLE published June 2005 in Toxicologic Pathology

Authors: Amy E. Brix | Abraham Nyska | Joseph K. Haseman | Donald M. Sells | Micheal P. Jokinen | Nigel J. Walker

Regulatory Forum Opinion Piece

JOURNAL ARTICLE published October 2012 in Toxicologic Pathology

Authors: Gerald G. Long | Jerry F. Hardisty

Early-Onset Asymptomatic Polypoid Cystitis in Two Adolescent Male Beagle Dogs

JOURNAL ARTICLE published August 2023 in Toxicologic Pathology

Authors: Giulia Tosi | Jennifer Rachael Barnes

Morphologic Considerations in the Interpretation of Gastrointestinal Disorders

JOURNAL ARTICLE published February 1988 in Toxicologic Pathology

Authors: Herbert J. Van Kruiningen

Effects of Microsomal Enzyme Inducers on Thyroid Follicular Cell Proliferation and Thyroid Hormone Metabolism

JOURNAL ARTICLE published January 2001 in Toxicologic Pathology

Authors: Curtis D. Klaassen | Alan M. Hood

Classification of Neural Tumors in Laboratory Rodents, Emphasizing the Rat

JOURNAL ARTICLE published January 2011 in Toxicologic Pathology

Authors: Klaus Weber | Robert H. Garman | Paul-Georg Germann | Jerry F. Hardisty | Georg Krinke | Peter Millar | Ingrid D. Pardo

Syk Inhibition Induces Platelet Dependent Peri-islet Hemorrhage in the Rat Pancreas

JOURNAL ARTICLE published October 2016 in Toxicologic Pathology

Authors: Andrew J. Long | Erik Sampson | Richard W. McCarthy | Christopher M. Harris | Marc Barnard | Dan Shi | Donna Conlon | Robert Caldwell | David Honor | Neil Wishart | Michael Hoemann | Lori Duggan | Douglas Fritz | Christopher Stedman | Elizabeth O’Connor | Igor Mikaelian | Annette Schwartz

Scientific and Regulatory Policy Committee Points to Consider*: Review of Scientific and Regulatory Policy Committee Points to Consider: Review of Current Practices for Ultrastructural Pathology Evaluations in Support of Nonclinical Toxicology Studies

JOURNAL ARTICLE published June 2019 in Toxicologic Pathology

Authors: Natalie D. Keirstead | Evan B. Janovitz | James T. Meehan | Bruce E. LeRoy | John R. Megill | Richard A. Peterson | Regis G. Masson | Heike A. Marxfeld

Diet, Genes, and Microbes

JOURNAL ARTICLE published January 2014 in Toxicologic Pathology

Authors: Diane F. Birt | Gregory J. Phillips