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Combination p53 activation and BCL-xL/BCL-2 inhibition as a therapeutic strategy in high-risk and relapsed acute lymphoblastic leukemia

JOURNAL ARTICLE published 10 April 2024 in Leukemia

Authors: Hayden L. Bell | Helen J. Blair | Samantha J. Jepson Gosling | Martin Galler | Daniel Astley | Anthony V. Moorman | Olaf Heidenreich | Gareth J. Veal | Frederik W. van Delft | John Lunec | Julie A. E. Irving

https://doi.org/10.1038/s41375-024-02241-7 Actions

Dual inhibition of EZH1/2 breaks the quiescence of leukemia stem cells in acute myeloid leukemia

JOURNAL ARTICLE published April 2018 in Leukemia

Authors: S Fujita | D Honma | N Adachi | K Araki | E Takamatsu | T Katsumoto | K Yamagata | K Akashi | K Aoyama | A Iwama | I Kitabayashi

https://doi.org/10.1038/leu.2017.300 Actions

Detection of BCR-ABL transcripts in chronic myeloid leukemia (CML) using a ‘real time’ quantitative RT-PCR assay

JOURNAL ARTICLE published 1 June 1999 in Leukemia

Authors: C Preudhomme | F Révillion | A Merlat | L Hornez | C Roumier | N Duflos-Grardel | JP Jouet | A Cosson | JP Peyrat | P Fenaux

https://doi.org/10.1038/sj.leu.2401426 Actions

Detection of leukemia-associated mutations in peripheral blood DNA of hematologically normal elderly individuals

JOURNAL ARTICLE published July 2015 in Leukemia

Authors: J Score | A Chase | L A Forsberg | L Feng | K Waghorn | A V Jones | C Rasi | D C Linch | J P Dumanski | R E Gale | N C P Cross

https://doi.org/10.1038/leu.2015.13 Actions

Prognostic significance of whole-body MRI in patients with monoclonal gammopathy of undetermined significance

JOURNAL ARTICLE published January 2014 in Leukemia

Authors: J Hillengass | M-A Weber | K Kilk | K Listl | B Wagner-Gund | M Hillengass | T Hielscher | A Farid | K Neben | S Delorme | O Landgren | H Goldschmidt

https://doi.org/10.1038/leu.2013.244 Actions

Cell origin of pyothorax-associated lymphoma: a lymphoma strongly associated with Epstein–Barr virus infection

JOURNAL ARTICLE published March 2008 in Leukemia

Authors: T Takakuwa | K Tresnasari | N Rahadiani | H Miwa | M Daibata | K Aozasa

https://doi.org/10.1038/sj.leu.2405059 Actions

BIN1 tumor suppressor regulates Fas/Fas ligand–mediated apoptosis through c-FLIP in cutaneous T-cell lymphoma

JOURNAL ARTICLE published June 2015 in Leukemia

Authors: S Esmailzadeh | Y Huang | M-W Su | Y Zhou | X Jiang

https://doi.org/10.1038/leu.2015.9 Actions

Abnormal mRNA expression of ASPP members in leukemia cell lines

JOURNAL ARTICLE published 1 April 2004 in Leukemia

Authors: Z-J Liu | Y Zhang | X-B Zhang | X Yang

https://doi.org/10.1038/sj.leu.2403300 Actions

Sex-associated differences in frequencies and prognostic impact of recurrent genetic alterations in adult acute myeloid leukemia (Alliance, AMLCG)

JOURNAL ARTICLE published January 2024 in Leukemia

Authors: Michael Ozga | Deedra Nicolet | Krzysztof Mrózek | Ayse S. Yilmaz | Jessica Kohlschmidt | Karilyn T. Larkin | James S. Blachly | Christopher C. Oakes | Jill Buss | Christopher J. Walker | Shelley Orwick | Vindi Jurinovic | Maja Rothenberg-Thurley | Annika Dufour | Stephanie Schneider | Maria Cristina Sauerland | Dennis Görlich | Utz Krug | Wolfgang E. Berdel | Bernhard J. Woermann | Wolfgang Hiddemann | Jan Braess | Marion Subklewe | Karsten Spiekermann | Andrew J. Carroll | William G. Blum | Bayard L. Powell | Jonathan E. Kolitz | Joseph O. Moore | Robert J. Mayer | Richard A. Larson | Geoffrey L. Uy | Wendy Stock | Klaus H. Metzeler | H. Leighton Grimes | John C. Byrd | Nathan Salomonis | Tobias Herold | Alice S. Mims | Ann-Kathrin Eisfeld

https://doi.org/10.1038/s41375-023-02068-8 Actions

Constitutive activation of STAT3 in Sézary syndrome is independent of SHP-1

JOURNAL ARTICLE published February 2012 in Leukemia

Authors: R C T McKenzie | C L Jones | I Tosi | J A Caesar | S J Whittaker | T J Mitchell

https://doi.org/10.1038/leu.2011.198 Actions

Intrahospital supervised exercise training: a complementary tool in the therapeutic armamentarium against childhood leukemia

JOURNAL ARTICLE published 1 August 2005 in Leukemia

Authors: A Lucia | M Ramírez | A F San Juan | S J Fleck | J García-Castro | L Madero

https://doi.org/10.1038/sj.leu.2403799 Actions

Unique CDR3 epitope targeting by CAR-T cells is a viable approach for treating T-cell malignancies

JOURNAL ARTICLE published September 2019 in Leukemia

Authors: Jinqi Huang | Stepanov Alexey | Jian Li | Terri Jones | Geramie Grande | Lacey Douthit | Jun Xie | Danna Chen | Xiaolei Wu | Maschan Michael | Changchun Xiao | Jiangning Zhao | Xuehua Xie | Jia Xie | Xiao Lei Chen | Guo Fu | Gabibov Alexander | Chi-Meng Tzeng

https://doi.org/10.1038/s41375-019-0455-3 Actions

Pathobiology of NPM-ALK and variant fusion genes in anaplastic large cell lymphoma and other lymphomas

JOURNAL ARTICLE published 1 September 2000 in Leukemia

Authors: HG Drexler | SM Gignac | R von Wasielewski | M Werner | WG Dirks

https://doi.org/10.1038/sj.leu.2401878 Actions

Metabolic plasticity in CLL: adaptation to the hypoxic niche

JOURNAL ARTICLE published January 2016 in Leukemia

Authors: K M Koczula | C Ludwig | R Hayden | L Cronin | G Pratt | H Parry | D Tennant | M Drayson | C M Bunce | F L Khanim | U L Günther

https://doi.org/10.1038/leu.2015.187 Actions

Treatment patterns for AL amyloidosis after frontline daratumumab, bortezomib, cyclophosphamide, and dexamethasone treatment failures

JOURNAL ARTICLE published 9 April 2024 in Leukemia

Authors: Saurabh Zanwar | Morie A. Gertz | Eli Muchtar | Francis K. Buadi | Taxiarchis Kourelis | Wilson Gonsalves | Ronald S. Go | Suzanne Hayman | Prashant Kapoor | Moritz Binder | Joselle Cook | David Dingli | Nelson Leung | Yi Lin | Rahma Warsame | Amie Fonder | Miriam Hobbs | Yi Lisa Hwa | Robert A. Kyle | S. Vincent Rajkumar | Shaji Kumar | Angela Dispenzieri

https://doi.org/10.1038/s41375-024-02243-5 Actions

An “off-the-shelf” CD2 universal CAR-T therapy for T-cell malignancies

JOURNAL ARTICLE published December 2023 in Leukemia

Research funded by U.S. Department of Health & Human Services | NIH | National Cancer Institute (CA210084,CA091842) | U.S. Department of Health & Human Services | National Institutes of Health (CA171963)

Authors: Jingyu Xiang | Jessica M. Devenport | Alun J. Carter | Karl W. Staser | Miriam Y. Kim | Julie O’ Neal | Julie K. Ritchey | Michael P. Rettig | Feng Gao | Garrett Rettig | Rolf Turk | Byung Ha Lee | Matthew L. Cooper | John F. DiPersio

https://doi.org/10.1038/s41375-023-02039-z Actions

The calcineurin protein phosphatase is dispensable for BCR-ABL-induced B-ALL maintenance, propagation and response to dasatinib

JOURNAL ARTICLE published January 2017 in Leukemia

Authors: F Rocchetti | C Tran Quang | A L Maragno | J Nguyen | C Lasgi | J Ghysdael

https://doi.org/10.1038/leu.2016.269 Actions

Altered expression of tumor suppressor PHF20 in myeloproliferative neoplasms

JOURNAL ARTICLE published August 2014 in Leukemia

Authors: T L Lasho | A Pardanani | A Tefferi | D I Smith

https://doi.org/10.1038/leu.2014.117 Actions

Gene expression signatures of pediatric myelodysplastic syndromes are associated with risk of evolution into acute myeloid leukemia

JOURNAL ARTICLE published July 2012 in Leukemia

Authors: S Bresolin | L Trentin | M Zecca | M Giordan | L Sainati | F Locatelli | G Basso | G te Kronnie

https://doi.org/10.1038/leu.2012.35 Actions

High ZAP-70 expression correlates with worse clinical outcome in mantle cell lymphoma

JOURNAL ARTICLE published 1 October 2006 in Leukemia

Authors: D Hui | L Dabbagh | J Hanson | H M Amin | R Lai

https://doi.org/10.1038/sj.leu.2404362 Actions
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