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Antioxidant Properties of 2,3-Dimethoxy-5-methyl- 6-(10-hydroxydecyl)-1,4-benzoquinone (Idebenone)

JOURNAL ARTICLE published 1 January 1998 in Chemical Research in Toxicology

Authors: Alvaro Mordente | Giuseppe E. Martorana | Giorgio Minotti | Bruno Giardina

https://doi.org/10.1021/tx970136j Actions

Genotoxic Mechanisms of Asbestos Fibers:  Role of Extranuclear Targets

JOURNAL ARTICLE published 1 May 2007 in Chemical Research in Toxicology

Authors: An Xu | Xuelian Huang | Yu-Chin Lien | Lingzhi Bao | Zengliang Yu | Tom K. Hei

https://doi.org/10.1021/tx600364d Actions

Evaluation of TOPKAT, Toxtree, and Derek Nexus in Silico Models for Ocular Irritation and Development of a Knowledge-Based Framework To Improve the Prediction of Severe Irritation

JOURNAL ARTICLE published 16 May 2016 in Chemical Research in Toxicology

Authors: Barun Bhhatarai | Daniel M. Wilson | Amanda K. Parks | Edward W. Carney | Pamela J. Spencer

https://doi.org/10.1021/acs.chemrestox.5b00531 Actions

Coupling Products of Nucleosides with the Glyoxal Adduct of Deoxyguanosine

JOURNAL ARTICLE published 1 August 2004 in Chemical Research in Toxicology

Authors: Angela K. Brock | Ivan D. Kozekov | Carmelo J. Rizzo | Thomas M. Harris

https://doi.org/10.1021/tx049906z Actions

4D-Fingerprint Categorical QSAR Models for Skin Sensitization Based on the Classification of Local Lymph Node Assay Measures

JOURNAL ARTICLE published 1 January 2007 in Chemical Research in Toxicology

Authors: Yi Li | Yufeng J. Tseng | Dahua Pan | Jianzhong Liu | Petra S. Kern | G. Frank Gerberick | Anton J. Hopfinger

https://doi.org/10.1021/tx6002535 Actions

Determination of Exposure Multiples of Human Metabolites for MIST Assessment in Preclinical Safety Species without Using Reference Standards or Radiolabeled Compounds

JOURNAL ARTICLE published 20 December 2010 in Chemical Research in Toxicology

Authors: Shuguang Ma | Zhiling Li | Keun-Joong Lee | Swapan K. Chowdhury

https://doi.org/10.1021/tx100363k Actions

Chemical and Enzymatic Oxidation of Furosemide: Formation of Pyridinium Salts

JOURNAL ARTICLE published 1 December 2007 in Chemical Research in Toxicology

Authors: Ling-Jen Chen | Leo T. Burka

https://doi.org/10.1021/tx700262z Actions

A Comprehensive Support Vector Machine Binary hERG Classification Model Based on Extensive but Biased End Point hERG Data Sets

JOURNAL ARTICLE published 20 June 2011 in Chemical Research in Toxicology

Authors: Meng-yu Shen | Bo-Han Su | Emilio Xavier Esposito | Anton J. Hopfinger | Yufeng J. Tseng

https://doi.org/10.1021/tx200099j Actions

DNA Adduct Formation by 2,6-Dimethyl-, 3,5-Dimethyl-, and 3-Ethylaniline in Vivo in Mice

JOURNAL ARTICLE published 1 August 2006 in Chemical Research in Toxicology

Authors: Paul L. Skipper | Laura J. Trudel | Thomas W. Kensler | John D. Groopman | Patricia A. Egner | Rosa G. Liberman | Gerald N. Wogan | Steven R. Tannenbaum

https://doi.org/10.1021/tx060082q Actions

Expression in Escherichia coli of the flavin-containing monooxygenase D (form II) from adult human liver: Determination of a distinct tertiary amine substrate specificity

JOURNAL ARTICLE published July 1993 in Chemical Research in Toxicology

Authors: Noureddine Lomri | Zicheng Yang | John R. Cashman

https://doi.org/10.1021/tx00034a006 Actions

Microprobe XRF Mapping and XAS Investigations of the Intracellular Metabolism of Arsenic for Understanding Arsenic-Induced Toxicity

JOURNAL ARTICLE published 15 September 2008 in Chemical Research in Toxicology

Authors: Kristie L. Munro | Anna Mariana | Andrejs I. Klavins | Amalanie J. Foster | Barry Lai | Stefan Vogt | ZhongHou Cai | Hugh H. Harris | Carolyn T. Dillon

https://doi.org/10.1021/tx800128d Actions

Comparative anticholinesterase potency of chiral isoparathion methyl

JOURNAL ARTICLE published September 1991 in Chemical Research in Toxicology

Authors: Seungmin Ryu | Jing Lin | Charles M. Thompson

https://doi.org/10.1021/tx00023a004 Actions

Effects of N2-Alkylguanine, O6-Alkylguanine, and Abasic Lesions on DNA Binding and Bypass Synthesis by the Euryarchaeal B-Family DNA Polymerase Vent (exo–)

JOURNAL ARTICLE published 20 August 2012 in Chemical Research in Toxicology

Authors: Seonhee Lim | Insil Song | F. Peter Guengerich | Jeong-Yun Choi

https://doi.org/10.1021/tx300168p Actions

Experimental and theoretical study on the redox cycling of resorufin by solubilized and membrane-bound NADPH-cytochrome reductase

JOURNAL ARTICLE published March 1992 in Chemical Research in Toxicology

Authors: Walter G. Balvers | Marelle G. Boersma | Jacques Vervoort | Ivonne M. C. M. Rietjens

https://doi.org/10.1021/tx00026a019 Actions

Paraquat Treatment Compromises the Clearance of β-Amyloid and Tau Proteins and Induces Primary Hippocampal Neuronal Cell Death through HSP70, P20S, and TFEB Disruption

JOURNAL ARTICLE published 17 May 2021 in Chemical Research in Toxicology

Research funded by Universidad Complutense de Madrid (PR26/20326) | Banco Santander (PR26/20326)

Authors: Paula Moyano | Javier Sanjuna | José Manuel Garcia | Jimena Garcia | María Teresa Frejo | María Victoria Naval | Javier del Pino

https://doi.org/10.1021/acs.chemrestox.0c00370 Actions

Heterocyclic derivatives of 3-substituted-1,1,1-trifluoro-2-propanones as inhibitors of esterolytic enzymes

JOURNAL ARTICLE published July 1990 in Chemical Research in Toxicology

Authors: Andras Szekacs | Premjit P. Halarnkar | Marilyn M. Olmstead | Kathleen A. Prag | Bruce D. Hammock

https://doi.org/10.1021/tx00016a009 Actions

S-Arylcysteine−Keratin Adducts as Biomarkers of Human Dermal Exposure to Aromatic Hydrocarbons

JOURNAL ARTICLE published 1 April 2008 in Chemical Research in Toxicology

Authors: Juei-Chuan C. Kang-Sickel | Donii D. Fox | Tae-gyu Nam | Karupiah Jayaraj | Louise M. Ball | John E. French | David G. Klapper | Avram Gold | Leena A. Nylander-French

https://doi.org/10.1021/tx7003773 Actions

Identification of 3,N4-Etheno-5-methyl-2′-deoxycytidine in Human DNA: A New Modified Nucleoside Which May Perturb Genome Methylation

JOURNAL ARTICLE published 13 January 2012 in Chemical Research in Toxicology

Authors: Jagadeesan Nair | Roger W. Godschalk | Urmila Nair | Robert W. Owen | William E. Hull | Helmut Bartsch

https://doi.org/10.1021/tx200392a Actions

Camptothecin Efficacy to Poison Top1 Is Altered by Bisphenol A in Mouse Embryonic Fibroblasts

JOURNAL ARTICLE published 18 June 2018 in Chemical Research in Toxicology

Research funded by National Institute of Environmental Health Sciences (ES021116,ES023813) | National Cancer Institute (CA148629)

Authors: Manoj Sonavane | Peter Sykora | Joel F. Andrews | Robert W. Sobol | Natalie R. Gassman

https://doi.org/10.1021/acs.chemrestox.8b00050 Actions

Analysis of Pyridyloxobutyl and Pyridylhydroxybutyl DNA Adducts in Extrahepatic Tissues of F344 Rats Treated Chronically with 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone and Enantiomers of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol

JOURNAL ARTICLE published 18 May 2009 in Chemical Research in Toxicology

Authors: Siyi Zhang | Mingyao Wang | Peter W. Villalta | Bruce R. Lindgren | Pramod Upadhyaya | Yanbin Lao | Stephen S. Hecht

https://doi.org/10.1021/tx900015d Actions
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