Effects of N²-Alkylguanine, O⁶-Alkylguanine, and Abasic Lesions on DNA Binding and Bypass Synthesis by the Euryarchaeal B-Family DNA Polymerase Vent (exo^–)

JOURNAL ARTICLE published 20 August 2012 in Chemical Research in Toxicology

Authors: Seonhee Lim | Insil Song | F. Peter Guengerich | Jeong-Yun Choi

Unraveling Reversible DNA Cross-Links with a Biological Machine

JOURNAL ARTICLE published 16 November 2020 in Chemical Research in Toxicology

Research funded by Division of Chemistry (CHE-1405123)

Authors: Shane R. Byrne | Steven E. Rokita

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JOURNAL ARTICLE published 16 November 2020 in Chemical Research in Toxicology

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JOURNAL ARTICLE published 16 August 2021 in Chemical Research in Toxicology

The Effects of Immune Modulators on Amodiaquine-Induced Liver Injury

JOURNAL ARTICLE published 20 August 2018 in Chemical Research in Toxicology

Authors: Alastair Mak | Tiffany Elizabeth Cho | Jack Uetrecht

Diclofenac Sodium Triggers p53-Dependent Apoptosis in Human Corneal Epithelial Cells via ROS-Mediated Crosstalk

JOURNAL ARTICLE published 18 January 2021 in Chemical Research in Toxicology

Research funded by Ministry of Science and Technology of the People's Republic of China (2017YFE0103500) | National Natural Science Foundation of China (31601104)

Authors: Hui Li | Ting-Jun Fan | Ping Zou | Bin Xu

Spotlight

JOURNAL ARTICLE published 21 October 2013 in Chemical Research in Toxicology

Authors: Heidi A. Dahlmann

Introducing Perspectives on Statistical Trends (POST)

JOURNAL ARTICLE published 16 December 2013 in Chemical Research in Toxicology

Authors: Stephen S. Hecht

Spotlight

JOURNAL ARTICLE published 18 February 2011 in Chemical Research in Toxicology

Authors: Carol A. Rouzer

Kinetics and Mechanistic Studies of the Hydrolysis of Diisocyanate-Derived Bis-thiocarbamates of Cysteine Methyl Ester

JOURNAL ARTICLE published 1 March 2006 in Chemical Research in Toxicology

Authors: Itai Chipinda | Sarah J. Stetson | Gary J. Depree | Reuben H. Simoyi | Paul D. Siegel

Dietary Polyphenols as Topoisomerase II Poisons: B Ring and C Ring Substituents Determine the Mechanism of Enzyme-Mediated DNA Cleavage Enhancement

JOURNAL ARTICLE published 1 June 2008 in Chemical Research in Toxicology

Authors: Omari J. Bandele | Sara J. Clawson | Neil Osheroff

Detection and Characterization of Two Major Ethylated Deoxyguanosine Adducts by High Performance Liquid Chromatography, Electrospray Mass Spectrometry, and ³²P-Postlabeling. Development of an Approach for Detection of Phosphotriesters

JOURNAL ARTICLE published 1 January 1997 in Chemical Research in Toxicology

Authors: Rajinder Singh | Gavain M. A. Sweetman | Peter B. Farmer | David E. G. Shuker | Kim J. Rich

Differential Activation of TRPA1 by Diesel Exhaust Particles: Relationships between Chemical Composition, Potency, and Lung Toxicity

JOURNAL ARTICLE published 17 June 2019 in Chemical Research in Toxicology

Research funded by National Institute of Environmental Health Sciences (ES017431,ES027015)

Authors: Cassandra E. Deering-Rice | Tosifa Memon | Zhenyu Lu | Erin G. Romero | James Cox | Thomas Taylor-Clark | John M. Veranth | Christopher A. Reilly

A Novel Lipidomics-Based Approach to Evaluating the Risk of Clinical Hepatotoxicity Potential of Drugs in 3D Human Microtissues

JOURNAL ARTICLE published 21 January 2020 in Chemical Research in Toxicology

Authors: Laura Goracci | Aurora Valeri | Simone Sciabola | Michael D. Aleo | Wolfgang Moritz | Jan Lichtenberg | Gabriele Cruciani

Metabolites in Safety Testing (MIST): Considerations of Mechanisms of Toxicity with Dose, Abundance, and Duration of Treatment

JOURNAL ARTICLE published 16 February 2009 in Chemical Research in Toxicology

Authors: Dennis A. Smith | R. Scott Obach

DNA adducts from carcinogenic and noncarcinogenic enantiomers of benzo[a]pyrenedihydrodiol epoxide

JOURNAL ARTICLE published September 1989 in Chemical Research in Toxicology

Authors: Shee Chau Cheng | Bruce D. Hilton | John M. Roman | Anthony Dipple

Kynurenine Signaling Increases DNA Polymerase Kappa Expression and Promotes Genomic Instability in Glioblastoma Cells

JOURNAL ARTICLE published 19 January 2016 in Chemical Research in Toxicology

Research funded by National Center for Advancing Translational Sciences (UL1TR000039) | National Cancer Institute (R01CA185893) | Division of Graduate Education (DGE 1452779)

Authors: April C.L. Bostian | Leena Maddukuri | Megan R. Reed | Tatsiana Savenka | Jessica H. Hartman | Lauren Davis | Dakota L. Pouncey | Grover P. Miller | Robert L. Eoff

High-Fat Diets Alter the Modulatory Effects of Xenobiotics on Cytochrome P450 Activities

JOURNAL ARTICLE published 21 May 2018 in Chemical Research in Toxicology

Research funded by National Institute of Environmental Health Sciences (U54 ES016015,P42 ES016465)

Authors: Natalie C. Sadler | Bobbie-Jo M. Webb-Robertson | Therese R. Clauss | Joel G. Pounds | Richard Corley | Aaron T. Wright

Toxic Metabolite Formation from Troglitazone (TGZ): New Insights from a DFT Study

JOURNAL ARTICLE published 18 July 2011 in Chemical Research in Toxicology

Authors: Vaibhav A. Dixit | Prasad V. Bharatam

Truncation, Deamidation, and Oxidation of Histone H2B in Cells Cultured with Nickel(II)

JOURNAL ARTICLE published 1 December 2005 in Chemical Research in Toxicology

Authors: Aldona A. Karaczyn | Filip Golebiowski | Kazimierz S. Kasprzak