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Mass Spectrometric Quantitation of N′-Nitrosonornicotine-1N-oxide in the Urine of Cigarette Smokers and Smokeless Tobacco Users

JOURNAL ARTICLE published 19 September 2022 in Chemical Research in Toxicology

Research funded by National Cancer Institute (CA-81301)

Authors: Yupeng Li | Stephen S. Hecht

https://doi.org/10.1021/acs.chemrestox.2c00195 Actions

S-Arylcysteine−Keratin Adducts as Biomarkers of Human Dermal Exposure to Aromatic Hydrocarbons

JOURNAL ARTICLE published 1 April 2008 in Chemical Research in Toxicology

Authors: Juei-Chuan C. Kang-Sickel | Donii D. Fox | Tae-gyu Nam | Karupiah Jayaraj | Louise M. Ball | John E. French | David G. Klapper | Avram Gold | Leena A. Nylander-French

https://doi.org/10.1021/tx7003773 Actions

Characterization of a Chemically Reactive Propranolol Metabolite That Binds to Microsomal Proteins of Rat Liver

JOURNAL ARTICLE published July 1995 in Chemical Research in Toxicology

Authors: Shizuo Narimatsu | Toshiyuki Watanabe | Yasuhiro Masubuchi | Toshiharu Horie | Yoshito Kumagai | Arthur K. Cho | Susumu Imaoka | Yoshihiko Funae | Tsutomu Ishikawa | Tokuji Suzuki

https://doi.org/10.1021/tx00047a012 Actions

Heterocyclic derivatives of 3-substituted-1,1,1-trifluoro-2-propanones as inhibitors of esterolytic enzymes

JOURNAL ARTICLE published July 1990 in Chemical Research in Toxicology

Authors: Andras Szekacs | Premjit P. Halarnkar | Marilyn M. Olmstead | Kathleen A. Prag | Bruce D. Hammock

https://doi.org/10.1021/tx00016a009 Actions

Identification of 3,N4-Etheno-5-methyl-2′-deoxycytidine in Human DNA: A New Modified Nucleoside Which May Perturb Genome Methylation

JOURNAL ARTICLE published 13 January 2012 in Chemical Research in Toxicology

Authors: Jagadeesan Nair | Roger W. Godschalk | Urmila Nair | Robert W. Owen | William E. Hull | Helmut Bartsch

https://doi.org/10.1021/tx200392a Actions

Camptothecin Efficacy to Poison Top1 Is Altered by Bisphenol A in Mouse Embryonic Fibroblasts

JOURNAL ARTICLE published 18 June 2018 in Chemical Research in Toxicology

Research funded by National Institute of Environmental Health Sciences (ES021116,ES023813) | National Cancer Institute (CA148629)

Authors: Manoj Sonavane | Peter Sykora | Joel F. Andrews | Robert W. Sobol | Natalie R. Gassman

https://doi.org/10.1021/acs.chemrestox.8b00050 Actions

In Vitro Biotransformation of the Nrf2 Activator Bardoxolone: Formation of an Epoxide Metabolite That Undergoes Two Novel Glutathione-Mediated Metabolic Pathways: Epoxide Reduction and Oxidative Elimination of Nitrile Moiety

JOURNAL ARTICLE published 18 November 2019 in Chemical Research in Toxicology

Research funded by National Institute of Environmental Health Sciences (P30 ES013508)

Authors: Amin M. Kamel | Stephen Bowlin | Ban Anwar | Holly Reichard | Joe Argus | Ian A. Blair

https://doi.org/10.1021/acs.chemrestox.9b00289 Actions

Bisdihydrodiols, rather than dihydrodiol oxides, are the principal microsomal metabolites of tumorigenic trans-3,4-dihydroxy-3,4-dihydrodibenz[a,h]anthracene

JOURNAL ARTICLE published January 1994 in Chemical Research in Toxicology

Authors: Karl L. Platt | Michael Schollmeier

https://doi.org/10.1021/tx00037a014 Actions

Experimental and theoretical study on the redox cycling of resorufin by solubilized and membrane-bound NADPH-cytochrome reductase

JOURNAL ARTICLE published March 1992 in Chemical Research in Toxicology

Authors: Walter G. Balvers | Marelle G. Boersma | Jacques Vervoort | Ivonne M. C. M. Rietjens

https://doi.org/10.1021/tx00026a019 Actions

Issue Publication Information

JOURNAL ARTICLE published 19 June 2023 in Chemical Research in Toxicology

https://doi.org/10.1021/txv036i006_1693866 Actions

Chemical and Enzymatic Reductive Activation of Acylfulvene to Isomeric Cytotoxic Reactive Intermediates

JOURNAL ARTICLE published 21 November 2011 in Chemical Research in Toxicology

Authors: Kathryn E. Pietsch | James F. Neels | Xiang Yu | Jiachang Gong | Shana J. Sturla

https://doi.org/10.1021/tx200401u Actions

The Cyclopentenone Product of Lipid Peroxidation, 15-A2t-Isoprostane (8-Isoprostaglandin A2), Is Efficiently Conjugated with Glutathione by Human and Rat Glutathione Transferase A4-4

JOURNAL ARTICLE published 1 September 2002 in Chemical Research in Toxicology

Authors: Ina Hubatsch | Bengt Mannervik | Ling Gao | L. Jackson Roberts | Yan Chen | Jason D. Morrow

https://doi.org/10.1021/tx020027r Actions

Gastrointestinal Toxicity, Antiinflammatory Activity, and Superoxide Dismutase Activity of Copper and Zinc Complexes of the Antiinflammatory Drug Indomethacin

JOURNAL ARTICLE published 1 January 2003 in Chemical Research in Toxicology

Authors: Carolyn T. Dillon | Trevor W. Hambley | Brendan J. Kennedy | Peter A. Lay | Qingdi Zhou | Neal M. Davies | J. Ray Biffin | Hubert L. Regtop

https://doi.org/10.1021/tx020078o Actions

Bioactivation of Fluorinated 2-Aryl-benzothiazole Antitumor Molecules by Human Cytochrome P450s 1A1 and 2W1 and Deactivation by Cytochrome P450 2S1

JOURNAL ARTICLE published 20 August 2012 in Chemical Research in Toxicology

Authors: Kai Wang | F. Peter Guengerich

https://doi.org/10.1021/tx3001994 Actions

Computer-Aided Knowledge Generation for Understanding Skin Sensitization Mechanisms: The TOPS-MODE Approach

JOURNAL ARTICLE published 1 October 2003 in Chemical Research in Toxicology

Authors: Ernesto Estrada | Grace Patlewicz | Mark Chamberlain | David Basketter | Sue Larbey

https://doi.org/10.1021/tx034093k Actions

Computational Studies on Biphenyl Derivatives. Analysis of the Conformational Mobility, Molecular Electrostatic Potential, and Dipole Moment of Chlorinated Biphenyl:  Searching for the Rationalization of the Selective Toxicity of Polychlorinated Biphenyls (PCBs)

JOURNAL ARTICLE published 1 December 2002 in Chemical Research in Toxicology

Authors: Antonio Chana | Miguel A. Concejero | Mercedes de Frutos | María J. González | Bernardo Herradón

https://doi.org/10.1021/tx025596d Actions

Microprobe XRF Mapping and XAS Investigations of the Intracellular Metabolism of Arsenic for Understanding Arsenic-Induced Toxicity

JOURNAL ARTICLE published 15 September 2008 in Chemical Research in Toxicology

Authors: Kristie L. Munro | Anna Mariana | Andrejs I. Klavins | Amalanie J. Foster | Barry Lai | Stefan Vogt | ZhongHou Cai | Hugh H. Harris | Carolyn T. Dillon

https://doi.org/10.1021/tx800128d Actions

Expression in Escherichia coli of the flavin-containing monooxygenase D (form II) from adult human liver: Determination of a distinct tertiary amine substrate specificity

JOURNAL ARTICLE published July 1993 in Chemical Research in Toxicology

Authors: Noureddine Lomri | Zicheng Yang | John R. Cashman

https://doi.org/10.1021/tx00034a006 Actions

The Urine Proteome in Toxicology

JOURNAL ARTICLE published 15 June 2020 in Chemical Research in Toxicology

Research funded by Natural Science Foundation of Beijing Municipality (7172076) | Beijing Cooperative Construction Project (110651103) | the Fundamental Research Funds for the Central Universities (2020KJZX002) | National Key Research and Development Program of China (2016YFC1306300,2018YFC0910202)

Authors: Youhe Gao

https://doi.org/10.1021/acs.chemrestox.0c00126 Actions

Cardiotoxicity Hazard and Risk Characterization of ToxCast Chemicals Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes from Multiple Donors

JOURNAL ARTICLE published 20 September 2021 in Chemical Research in Toxicology

Research funded by National Institute of Environmental Health Sciences (ES026568,ES027704) | U.S. Environmental Protection Agency (RD83580201)

Authors: Sarah D. Burnett | Alexander D. Blanchette | Weihsueh A. Chiu | Ivan Rusyn

https://doi.org/10.1021/acs.chemrestox.1c00203 Actions
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