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Transimination of Quinone Imines: A Mechanism for Embedding Exogenous Redox Activity into the Nucleosome

JOURNAL ARTICLE published 17 December 2012 in Chemical Research in Toxicology

Authors: Wenjie Ye | Uthpala I. Seneviratne | Ming-Wei Chao | Kodihalli C. Ravindra | Gerald N. Wogan | Steven R. Tannenbaum | Paul L. Skipper

Biological Effects and Mechanism of Action of Farnesyl Transferase Inhibitors

JOURNAL ARTICLE published 1 October 2000 in Chemical Research in Toxicology

Authors: Hena R. Ashar | Lydia Armstrong | Linda J. James | Donna M. Carr | Kimberley Gray | Arthur Taveras | Ronald J. Doll | W. Robert Bishop | Paul T. Kirschmeier

Chronic Arsenic Exposure Increases Aβ(1–42) Production and Receptor for Advanced Glycation End Products Expression in Rat Brain

JOURNAL ARTICLE published 16 January 2018 in Chemical Research in Toxicology

Research funded by Secretar?a de Educaci?n P?blica (103.5/12/3953) | Consejo Nacional de Ciencia y Tecnolog?a (105937,232762,241009,276577,503319,DSA/103.5/16/7283) | Universidad Aut?noma de San Luis Potos? (CO9-FAI-03-21.21,P/PIFI-2012-24MSU0011E-13)

Authors: Sandra Aurora Niño | Guadalupe Martel-Gallegos | Adriana Castro-Zavala | Benita Ortega-Berlanga | Juan Manuel Delgado | Héctor Hernández-Mendoza | Elizabeth Romero-Guzmán | Judith Ríos-Lugo | Sergio Rosales-Mendoza | María E. Jiménez-Capdeville | Sergio Zarazúa

Time-Dependent Evolution of Adducts Formed between Deoxynucleosides and a Model Quinone Methide

JOURNAL ARTICLE published 1 September 2005 in Chemical Research in Toxicology

Authors: Emily E. Weinert | Kristen N. Frankenfield | Steven E. Rokita

Heavy-Metals-Mediated Phospholipids Scrambling by Human Phospholipid Scramblase 3: A Probable Role in Mitochondrial Apoptosis

JOURNAL ARTICLE published 17 February 2020 in Chemical Research in Toxicology

Authors: Santosh Kumar Palanirajan | Sathyanarayana N. Gummadi

Design, Synthesis, and Biological Activity of Hydrogen Peroxide Responsive Arylboronate Melatonin Hybrids

JOURNAL ARTICLE published 22 January 2019 in Chemical Research in Toxicology

Authors: Annalida Bedini | Alessandra Fraternale | Rita Crinelli | Michele Mari | Silvia Bartolucci | Laura Chiarantini | Gilberto Spadoni

Chlorine Substitution Pattern, Molecular Electronic Properties, and the Nature of the Ligand−Receptor Interaction:  Quantitative Property−Activity Relationships of Polychlorinated Dibenzofurans

JOURNAL ARTICLE published 1 February 2005 in Chemical Research in Toxicology

Authors: Shoji Hirokawa | Tomoko Imasaka | Totaro Imasaka

HU-331 Is a Catalytic Inhibitor of Topoisomerase IIα

JOURNAL ARTICLE published 15 December 2014 in Chemical Research in Toxicology

Research funded by Lipscomb University College of Pharmacy and Health Sciences (Pharmaceutical Sciences Summer Research Program)

Authors: Kellie M. Regal | Susan L. Mercer | Joseph E. Deweese

Biosynthesis and Transformation of Homoanatoxin-a in the Cyanobacterium Raphidiopsis mediterranea Skuja and Structures of Three New Homologues

JOURNAL ARTICLE published 1 December 2004 in Chemical Research in Toxicology

Authors: Michio Namikoshi | Tomokazu Murakami | Takeshi Fujiwara | Hiroshi Nagai | Takushi Niki | Emiko Harigaya | Mariyo F. Watanabe | Taiko Oda | Junko Yamada | Shigeo Tsujimura

Formation of Bulky DNA Adducts by Non-Enzymatic Production of 1,2-Naphthoquinone-Epoxide from 1,2-Naphthoquinone under Physiological Conditions

JOURNAL ARTICLE published 16 September 2019 in Chemical Research in Toxicology

Research funded by Japan Society for the Promotion of Science (26505010,17K00555)

Authors: Takuya Matsui | Naohito Yamada | Hideyuki Kuno | Robert A. Kanaly

Determining the Site of Spin Trapping of the Equine Myoglobin Radical by Combined Use of EPR, Electrophoretic Purification, and Mass Spectrometry

JOURNAL ARTICLE published 1 December 2002 in Chemical Research in Toxicology

Authors: Michael N. Harris | Scott W. Burchiel | Paul G. Winyard | John R. Engen | Charlotte D. Mobarak | Graham S. Timmins

Glutathione and N-acetylcysteine conjugates of 2-chloroethyl isocyanate. Identification as metabolites of N,N'-bis(2-chloroethyl)-N-nitrosourea in the rat and inhibitory properties toward glutathione reductase in vitro

JOURNAL ARTICLE published May 1993 in Chemical Research in Toxicology

Authors: Margaret R. Davis | Kelem Kassahun | Claudia M. Jochheim | Kathleen M. Brandt | Thomas A. Baillie

On the role of calcium in the toxicity of alkylating and oxidizing quinone imines in isolated hepatocytes

JOURNAL ARTICLE published January 1989 in Chemical Research in Toxicology

Authors: Pierluigi Nicotera | Mats Rundgren | David J. Porubek | Ian Cotgreave | Peter Moldeus | Sten Orrenius | Sidney D. Nelson

Mechanisms of DNA Damage by Leinamycin

JOURNAL ARTICLE published 1 October 2000 in Chemical Research in Toxicology

Authors: Kent S. Gates

Direct synthesis and identification of benzo[a]pyrenediol epoxide-deoxyguanosine binding sites in modified oligodeoxynucleotides

JOURNAL ARTICLE published November 1992 in Chemical Research in Toxicology

Authors: Bing Mao | Leonid A. Margulis | Bin Li | Victor Ibanez | Hongmee Lee | Ronald G. Harvey | Nicholas E. Geacintov

Adduction of the Chloroform Metabolite Phosgene to Lysine Residues of Human Histone H2B

JOURNAL ARTICLE published 1 March 2003 in Chemical Research in Toxicology

Authors: Laura Fabrizi | Graham W. Taylor | Benito Cañas | Alan R. Boobis | Robert J. Edwards

Molecular biomarkers for human chemical carcinogen exposures

JOURNAL ARTICLE published November 1993 in Chemical Research in Toxicology

Authors: John D. Groopman | Thomas W. Kensler

Activation of Carboplatin by Carbonate

JOURNAL ARTICLE published 1 January 2006 in Chemical Research in Toxicology

Authors: Anthony J. Di Pasqua | Jerry Goodisman | Deborah J. Kerwood | Bonnie B. Toms | Ronald L. Dubowy | James C. Dabrowiak

Effect of Methyl Substitution on the Antioxidative Property and Genotoxicity of Resveratrol

JOURNAL ARTICLE published 1 February 2008 in Chemical Research in Toxicology

Authors: Kiyoshi Fukuhara | Ikuo Nakanishi | Atsuko Matsuoka | Tomohiro Matsumura | Sachiko Honda | Mikiko Hayashi | Toshihiko Ozawa | Naoki Miyata | Shinichi Saito | Nobuo Ikota | Haruhiro Okuda

DNA Adducts as Biomarkers To Predict, Prevent, and Diagnose Disease—Application of Analytical Chemistry to Clinical Investigations

JOURNAL ARTICLE published 17 February 2020 in Chemical Research in Toxicology

Authors: Carlos Hernandez-Castillo | John Termini | Sarah Shuck