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Metabolism and Toxicity of Drugs. Two Decades of Progress in Industrial Drug Metabolism

JOURNAL ARTICLE published 1 January 2008 in Chemical Research in Toxicology

Authors: Thomas A. Baillie

https://doi.org/10.1021/tx7002273 Actions

Revision of the Biodistribution of Uranyl in Serum: Is Fetuin-A the Major Protein Target?

JOURNAL ARTICLE published 20 May 2013 in Chemical Research in Toxicology

Authors: Christian Basset | Olivier Averseng | Pierre-Jean Ferron | Nicolas Richaud | Agnès Hagège | Olivier Pible | Claude Vidaud

https://doi.org/10.1021/tx400048u Actions

Importance of Being Thiomethylated: Formation, Fate, and Effects of Methylated Thioarsenicals

JOURNAL ARTICLE published 16 March 2015 in Chemical Research in Toxicology

Research funded by National Natural Science Foundation of China (8127338,81473289) | Natural Science Foundation of Zhejiang Province (R2110231) | K.P. Chao's High Technology Development Foundation, Zhejiang University (2013RC026)

Authors: Qian Qian Wang | David J. Thomas | Hua Naranmandura

https://doi.org/10.1021/tx500464t Actions

Virtual Cross-Linking of the Active Nemorubicin Metabolite PNU-159682 to Double-Stranded DNA

JOURNAL ARTICLE published 20 February 2017 in Chemical Research in Toxicology

Research funded by Ministero dell'Istruzione, dell'Universita' e della Ricerca (PRIN: 2010W2KM5L_006)

Authors: Matteo Scalabrin | Luigi Quintieri | Manlio Palumbo | Federico Riccardi Sirtori | Barbara Gatto

https://doi.org/10.1021/acs.chemrestox.6b00362 Actions

Nicotelline: A Proposed Biomarker and Environmental Tracer for Particulate Matter Derived from Tobacco Smoke

JOURNAL ARTICLE published 18 November 2013 in Chemical Research in Toxicology

Authors: Peyton Jacob | Maciej L. Goniewicz | Christopher M. Havel | Suzaynn F. Schick | Neal L. Benowitz

https://doi.org/10.1021/tx400094y Actions

Association of Type 2 Diabetes with Submicron Titanium Dioxide Crystals in the Pancreas

JOURNAL ARTICLE published 18 June 2018 in Chemical Research in Toxicology

Research funded by Welch Foundation (F-1131)

Authors: Adam Heller | Karalee Jarvis | Sheryl S. Coffman

https://doi.org/10.1021/acs.chemrestox.8b00047 Actions

Effects of Arsenic on wnt/β-catenin Signaling Pathway: A Systematic Review and Meta-analysis

JOURNAL ARTICLE published 15 June 2020 in Chemical Research in Toxicology

Research funded by National Natural Science Foundation of China (81760584)

Authors: Shugang Li | Qingxin Ren

https://doi.org/10.1021/acs.chemrestox.0c00019 Actions

Site of Reactivity Models Predict Molecular Reactivity of Diverse Chemicals with Glutathione

JOURNAL ARTICLE published 20 April 2015 in Chemical Research in Toxicology

Authors: Tyler B. Hughes | Grover P. Miller | S. Joshua Swamidass

https://doi.org/10.1021/acs.chemrestox.5b00017 Actions

Covalent Binding of a Reactive Metabolite Derived from Propranolol and Its Active Metabolite 4-Hydroxypropranolol to Hepatic Microsomal Proteins of the Rat

JOURNAL ARTICLE published 1 March 1997 in Chemical Research in Toxicology

Authors: Shizuo Narimatsu | Takayuki Arai | Toshiyuki Watanabe | Yasuhiro Masubuchi | Toshiharu Horie | Tokuji Suzuki | Tsutomu Ishikawa | Michio Tsutsui | Yoshito Kumagai | Arthur K. Cho

https://doi.org/10.1021/tx960165e Actions

Safety Assessment of Nanomaterials for Antimicrobial Applications

JOURNAL ARTICLE published 18 May 2020 in Chemical Research in Toxicology

Research funded by Ministry of Science and Technology of the People's Republic of China (2016YFA0201600,2016YFE0133100) | Bureau of International Cooperation, Chinese Academy of Sciences (GJHG1852) | National Natural Science Foundation of China (11621505) | Chinese Academy of Sciences (QYZDJ-SSW-SLH022) | Research and Development Project in Key Areas of Guangdong Province (2019B090917011)

Authors: Arbab Ali | Muhammad Ovais | Xuejing Cui | YuKui Rui | Chunying Chen

https://doi.org/10.1021/acs.chemrestox.9b00519 Actions

In Vitro Toxicity and Chemical Characterization of Aerosol Derived from Electronic Cigarette Humectants Using a Newly Developed Exposure System

JOURNAL ARTICLE published 20 July 2020 in Chemical Research in Toxicology

Research funded by National Heart, Lung, and Blood Institute (3R01HL139369-01S1,P50 HL120100,R01HL139369)

Authors: Yael-Natalie H. Escobar | Grace Nipp | Tianqu Cui | Sarah S. Petters | Jason D. Surratt | Ilona Jaspers

https://doi.org/10.1021/acs.chemrestox.9b00490 Actions

Phototoxicity Associated with Diclofenac:  A Photophysical, Photochemical, and Photobiological Study on the Drug and Its Photoproducts

JOURNAL ARTICLE published 1 August 1998 in Chemical Research in Toxicology

Authors: Susana Encinas | Francisco Bosca | Miguel A. Miranda

https://doi.org/10.1021/tx9800708 Actions

Structures of a DNA Polymerase Inserting Therapeutic Nucleotide Analogues

JOURNAL ARTICLE published 20 November 2017 in Chemical Research in Toxicology

Research funded by U.S. Department of Health and Human Services (R00ES024431)

Authors: Matthew A. Schaich | Mallory R. Smith | Ashley S. Cloud | Sean M. Holloran | Bret D. Freudenthal

https://doi.org/10.1021/acs.chemrestox.7b00173 Actions

The Role of Cyclooxygenases-2 in Benzo(a)pyrene-Induced Neurotoxicity of Cortical Neurons

JOURNAL ARTICLE published 15 June 2020 in Chemical Research in Toxicology

Research funded by National Natural Science Foundation of China (21906098) | Shanxi Provincial Key Research and Development Project (201903D321078) | Project for Applied Basic Research of Shanxi Province (201701D221245)

Authors: Lin Guo | Mengjiao Wei | Ben Li | Yang Yun | Guangke Li | Nan Sang

https://doi.org/10.1021/acs.chemrestox.9b00451 Actions

Measurement of N7-(2‘-Hydroxyethyl)guanine in Human DNA by Gas Chromatography Electron Capture Mass Spectrometry

JOURNAL ARTICLE published 1 January 2005 in Chemical Research in Toxicology

Authors: Chi-Yu Kao | Roger W. Giese

https://doi.org/10.1021/tx049854d Actions

Validation of a Multiparametric, High-Content-Screening Assay for Predictive/Investigative Cytotoxicity: Evidence from Technology Transfer Studies and Literature Review

JOURNAL ARTICLE published 20 March 2017 in Chemical Research in Toxicology

Research funded by Enterprise Ireland (CC20080001)

Authors: Peter James O’Brien | Anna Edvardsson

https://doi.org/10.1021/acs.chemrestox.6b00403 Actions

Assessment of Pre- and Pro-haptens Using Nonanimal Test Methods for Skin Sensitization

JOURNAL ARTICLE published 16 May 2016 in Chemical Research in Toxicology

Authors: Daniel Urbisch | Matthias Becker | Naveed Honarvar | Susanne Noreen Kolle | Annette Mehling | Wera Teubner | Britta Wareing | Robert Landsiedel

https://doi.org/10.1021/acs.chemrestox.6b00055 Actions

Characterization of Genetic Variation in CYP3A4 on the Metabolism of Cabozantinib in Vitro

JOURNAL ARTICLE published 19 August 2019 in Chemical Research in Toxicology

Authors: Qian-meng Lin | Ying-hui Li | Xiang-ran Lu | Ru Wang | Ni-hong Pang | Ren-ai Xu | Jian-ping Cai | Guo-xin Hu

https://doi.org/10.1021/acs.chemrestox.9b00100 Actions

In vitro and In vivo Metabolism of the Carcinogen 4-Nitropyrene

JOURNAL ARTICLE published September 1994 in Chemical Research in Toxicology

Authors: Pramod Upadhyaya | Linda S. Von Tungeln | Peter P. Fu | Karam El-Bayoumy

https://doi.org/10.1021/tx00041a015 Actions

The enzymic formation and chemical reactivity of quinone methides correlate with alkylphenol-induced toxicity in rat hepatocytes

JOURNAL ARTICLE published November 1992 in Chemical Research in Toxicology

Authors: Judy L. Bolton | Luis G. Valerio | John A. Thompson

https://doi.org/10.1021/tx00030a014 Actions
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