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Synthesis, Conformation and T-Helper Cell Stimulation of an O-Linked Glycopeptide Epitope Containing Extended Carbohydrate Side-Chains

JOURNAL ARTICLE published December 2002 in Bioorganic & Medicinal Chemistry

Authors: Mare Cudic | Hildegund C.J Ertl | Laszlo Otvos

Synthesis and enzymatic activation of N-[Nα-(4-amino-4-deoxypteroyl)-Nδ-hemiphthaloyl-l-ornithiny]-l-phenylalanine, a candidate for antibody-directed enzyme prodrug therapy (ADEPT)

JOURNAL ARTICLE published March 2002 in Bioorganic & Medicinal Chemistry

Authors: Joel E Wright | Andre Rosowsky

A dual inhibitor of matrix metalloproteinases and a disintegrin and metalloproteinases, [18F]FB-ML5, as a molecular probe for non-invasive MMP/ADAM-targeted imaging

JOURNAL ARTICLE published January 2015 in Bioorganic & Medicinal Chemistry

Authors: Nathalie Matusiak | Riccardo Castelli | Adriaan W. Tuin | Herman S. Overkleeft | Rosalina Wisastra | Frank J. Dekker | Laurette M. Prély | Rainer P.H. Bischoff | Aren van Waarde | Rudi A.J.O. Dierckx | Philip H. Elsinga

Structure–activity relationship of cinnamic acylsulfonamide analogues on the human EP3 prostanoid receptor

JOURNAL ARTICLE published August 2001 in Bioorganic & Medicinal Chemistry

Authors: Hélène Juteau | Yves Gareau | Marc Labelle | Claudio F Sturino | Nicole Sawyer | Nathalie Tremblay | Sonia Lamontagne | Marie-Claude Carrière | Danielle Denis | Kathleen M Metters

New dsDNA binding unnatural oligopeptides with pyrimidine selectivity

JOURNAL ARTICLE published November 2002 in Bioorganic & Medicinal Chemistry

Authors: Zhenyu Zhang | Patrick Chaltin | Arthur Van Aerschot | Jeff Lacey | Jef Rozenski | Roger Busson | Piet Herdewijn

Preparation of two sets of 5,6,7-trioxygenated dihydroflavonol derivatives as free radical scavengers and neuronal cell protectors to oxidative damage

JOURNAL ARTICLE published May 2009 in Bioorganic & Medicinal Chemistry

Authors: Jingxu Gong | Kexin Huang | Feng Wang | Leixiang Yang | Yubing Feng | Haibo Li | Xiaokun Li | Su Zeng | Xiumei Wu | Joachim Stöckigt | Yu Zhao | Jia Qu

Introduction of non-natural amino acid residues into the substrate-specific P1 position of trypsin inhibitor SFTI-1 yields potent chymotrypsin and cathepsin G inhibitors

JOURNAL ARTICLE published May 2009 in Bioorganic & Medicinal Chemistry

Authors: Anna Łęgowska | Dawid Dębowski | Adam Lesner | Magdalena Wysocka | Krzysztof Rolka

Molecular dynamics simulations on the critical states of the farnesyltransferase enzyme

JOURNAL ARTICLE published May 2009 in Bioorganic & Medicinal Chemistry

Research funded by Fundação para a Ciência e a Tecnologia (POCI/QUI/61563/2004)

Authors: Sérgio Filipe Sousa | Pedro Alexandrino Fernandes | Maria João Ramos

A one step/one pot synthesis of N,N-bis(phosphonomethyl)amino acids and their effects on adipogenic and osteogenic differentiation of human mesenchymal stem cells

JOURNAL ARTICLE published May 2009 in Bioorganic & Medicinal Chemistry

Research funded by Österreichische Forschungsförderungsgesellschaft (FA 526003)

Authors: Johanna Kasser | Alexey A. Nazarov | Christian G. Hartinger | Brigitte Wdziekonski | Christian Dani | Maxim L. Kuznetsov | Vladimir B. Arion | Bernhard K. Keppler

Emission of characteristic fluorescence from the ligand–cytosine complex in U_A/ACU bulged RNA duplex

JOURNAL ARTICLE published July 2007 in Bioorganic & Medicinal Chemistry

Authors: Jinhua Zhang | Fumie Takei | Kazuhiko Nakatani

Mechanism of the melanogenesis stimulation activity of (−)-cubebin in murine B16 melanoma cells

JOURNAL ARTICLE published July 2007 in Bioorganic & Medicinal Chemistry

Authors: Noriko Hirata | Shunsuke Naruto | Kenji Ohguchi | Yukihiro Akao | Yoshinori Nozawa | Munekazu Iinuma | Hideaki Matsuda

Toward the development of chemoprevention agents. Part 1: Design, synthesis, and anti-inflammatory activities of a new class of 2,5-disubstituted-dioxacycloalkanes

JOURNAL ARTICLE published July 2007 in Bioorganic & Medicinal Chemistry

Authors: Keli Gu | Lanrong Bi | Ming Zhao | Chao Wang | Jingfang Ju | Shiqi Peng

The influence of the long chain fatty acid on the antagonistic activities of Rhizobium sin-1 lipid A

JOURNAL ARTICLE published July 2007 in Bioorganic & Medicinal Chemistry

Authors: Yanghui Zhang | Margreet A. Wolfert | Geert-Jan Boons

Design and synthesis of multivalent drug delivery system with CA IX inhibitors as ligands

JOURNAL ARTICLE published October 2023 in Bioorganic & Medicinal Chemistry

Research funded by National Natural Science Foundation of China (82104000)

Authors: Mengyuan Ding | Qiwen Zhu | Wei Lu | Shulei Zhu

Synthesis and biological evaluation of polymethoxylated 4-heteroarylcoumarins as tubulin assembly inhibitor

JOURNAL ARTICLE published October 2008 in Bioorganic & Medicinal Chemistry

Authors: Olga G. Ganina | Etienne Daras | Véronique Bourgarel-Rey | Vincent Peyrot | Alexey N. Andresyuk | Jean-Pierre Finet | Alexey Yu. Fedorov | Irina P. Beletskaya | Sébastien Combes

Translation of the copper/bipyridine-promoted Petasis reaction to solid phase-coupled DNA for encoded library synthesis

JOURNAL ARTICLE published May 2020 in Bioorganic & Medicinal Chemistry

Authors: Marco Potowski | Robin Esken | Andreas Brunschweiger

Discovery of a novel series of indoline carbamate and indolinylpyrimidine derivatives as potent GPR119 agonists

JOURNAL ARTICLE published March 2014 in Bioorganic & Medicinal Chemistry

Authors: Kenjiro Sato | Hiromichi Sugimoto | Kentaro Rikimaru | Hiroshi Imoto | Masahiro Kamaura | Nobuyuki Negoro | Yoshiyuki Tsujihata | Hirohisa Miyashita | Tomoyuki Odani | Toshiki Murata

Apoptosis-inducing effect of epolactaene derivatives on BALL-1 cells

JOURNAL ARTICLE published April 2006 in Bioorganic & Medicinal Chemistry

Authors: Kouji Kuramochi | Rie Matsui | Yasuaki Matsubara | Junko Nakai | Takashi Sunoki | Satoshi Arai | Seigo Nagata | Yukitoshi Nagahara | Yoshiyuki Mizushina | Masahiko Ikekita | Susumu Kobayashi

Design, synthesis and biological evaluation of a novel class of anticancer agents: Anthracenylisoxazole lexitropsin conjugates

JOURNAL ARTICLE published February 2009 in Bioorganic & Medicinal Chemistry

Authors: Xiaochun Han | Chun Li | Michael D. Mosher | Kevin C. Rider | Peiwen Zhou | Ronald L. Crawford | William Fusco | Andrzej Paszczynski | Nicholas R. Natale

Polyguluronate simulations shed light onto the therapeutic action of OligoG CF-5/20

JOURNAL ARTICLE published October 2022 in Bioorganic & Medicinal Chemistry

Authors: Oliver J. Hills | Chin W. Yong | Andrew J. Scott | James Smith | Helen F. Chappell