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Huntingtin Aggregation Impairs Autophagy, Leading to Argonaute-2 Accumulation and Global MicroRNA Dysregulation

Journal Article published Aug 2018 in Cell Reports volume 24 issue 6 on pages 1397 to 1406

Research funded by Vetenskapsrådet (K2014-62X-22527-01-3, K2014-62X-20404-08-5) | Stiftelsen för Strategisk Forskning (FFL12-0074) | Hjärnfonden (FO2014-0106) | Swedish Excellence Project Basal Ganglia Disorders Linnaeus Consortium (Bagadilico) | Swedish Government Initiative for Strategic Research Areas (MultiPark and StemTherapy)

Authors: Karolina Pircs, Rebecca Petri, Sofia Madsen, Per Ludvik Brattås, Romina Vuono, Daniella R. Ottosson, Isabelle St-Amour, Bob A. Hersbach, Monika Matusiak-Brückner, Sofia Hult Lundh, Åsa Petersén, Nicole Déglon, Sébastien S. Hébert, Malin Parmar, Roger A. Barker, Johan Jakobsson