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Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD–induced myeloproliferation

Journal Article published 21 Jun 2017 in The Journal of Experimental Medicine volume 214 issue 7 on pages 2005 to 2021

Research funded by Oxford Consortium for Single-Cell Biology (MR/M00919X/1) | Molecular Haematology Unit (MC_UU_12009) | Bloodwise | WIMM Strategic Alliance (G0902418, MC_UU_12025) | National Institute for Health Research | John Fell Fund (131/030, 101/517) | WIMM Flow Cytometry Facility | Wellcome Trust | Oxford Biomedical Research Centre | Human Immunology Unit | Medical Research Council (MR/L006340/1, G0801073, MC_UU_12009/5) | E.P. Abraham Research Fund (CF182, CF170) | Svenska Forskningsrådet Formas

Authors: Adam J. Mead, Wen Hao Neo, Nikolaos Barkas, Sahoko Matsuoka, Alice Giustacchini, Raffaella Facchini, Supat Thongjuea, Lauren Jamieson, Christopher A.G. Booth, Nicholas Fordham, Cristina Di Genua, Deborah Atkinson, Onima Chowdhury, Emmanouela Repapi, Nicki Gray, Shabnam Kharazi, Sally-Ann Clark, Tiphaine Bouriez, Petter Woll, Toshio Suda, Claus Nerlov, Sten Eirik W. Jacobsen