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Validation and development of MTH1 inhibitors for treatment of cancer

Journal Article published 8 Nov 2016 in Annals of Oncology volume 27 issue 12 on pages 2275 to 2283

Research funded by Västra Götalandsregionen (J.A.N., ALF-VGR-165661) | The Swiss National Science Foundation (F.Z.G., 148644 and 15635) | T.H., SSF/01-05 | BioCARE (J.A.N., TPOE-2013), VINNOVA (T.H., 2014-03480) | European Research Council (T.H., 268815, 62029) | Swedish Cancer Society (T.H., CAN 2012/770; J.A.N., 2013-3791) | The Knut and Alice Wallenberg Foundation (T.H., KAW 2014.0273; J.A.N., B.O.E., KAW 2014-0080) | Barncancerfonden (T.H., PR2014-0048, PR2013-0002; J.L., PR2014-0155; R.J., TJ2016-0035) | Vetenskapsrådet (T.H., 2012-5935; J.A.N., 2013-3791; J.L., 2012-5145 and 2015-04622: G.M., 2012-00327) | Torsten Söderbergs Stiftelse | Stiftelsen för Strategisk Forskning (T.H., RB13-0224; J.L., RIF14-0046)

Authors: U. Warpman Berglund, K. Sanjiv, H. Gad, C. Kalderén, T. Koolmeister, T. Pham, C. Gokturk, R. Jafari, G. Maddalo, B. Seashore-Ludlow, A. Chernobrovkin, A. Manoilov, I. S. Pateras, A. Rasti, A.-S. Jemth, I. Almlöf, O. Loseva, T. Visnes, B. O. Einarsdottir, F. Z. Gaugaz, A. Saleh, B. Platzack, O. A. Wallner, K. S. A. Vallin, M. Henriksson, P. Wakchaure, S. Borhade, P. Herr, Y. Kallberg, P. Baranczewski, E. J. Homan, E. Wiita, V. Nagpal, T. Meijer, N. Schipper, S. G. Rudd, L. Bräutigam, A. Lindqvist, A. Filppula, T-C. Lee, P. Artursson, J. A. Nilsson, V. G. Gorgoulis, J. Lehtiö, R. A. Zubarev, M. Scobie, T. Helleday