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Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach

Journal Article published 17 Jan 2017 in PLOS Medicine volume 14 issue 1 on page e1002215

Research funded by Australian Research Council (FT0991360) | Lifelong Health and Wellbeing Initiative (MR/K026992/1) | Boston Children's Hospital (Tommy Kaplan Fund) | Age UK | The Chief Scientist Office of the Scottish Government | National Health and Medical Research Council (613608, APP496667, APP1010374 and APP1046880, 613602, 613602) | National Heart, Lung, and Blood Institute (N01-HC-25195, HHSN268201500001I, Director's Challenge Award) | Centre for Cognitive Ageing and Cognitive Epidemiology (Pilot Fund award) | National Institutes of Health (P30 DK46200) | Wellcome Trust (Strategic Support Fund) | Biotechnology and Biological Sciences Research Council | Medical Research Council | University of Queensland | Economic and Social Research Council | Royal Society | Center for Information Technology (Computational resources of the Biowulf system) | University of Edinburgh

Authors: Michael M. Mendelson, Riccardo E. Marioni, Roby Joehanes, Chunyu Liu, Åsa K. Hedman, Stella Aslibekyan, Ellen W. Demerath, Weihua Guan, Degui Zhi, Chen Yao, Tianxiao Huan, Christine Willinger, Brian Chen, Paul Courchesne, Michael Multhaup, Marguerite R. Irvin, Ariella Cohain, Eric E. Schadt, Megan L. Grove, Jan Bressler, Kari North, Johan Sundström, Stefan Gustafsson, Sonia Shah, Allan F. McRae, Sarah E. Harris, Jude Gibson, Paul Redmond, Janie Corley, Lee Murphy, John M. Starr, Erica Kleinbrink, Leonard Lipovich, Peter M. Visscher, Naomi R. Wray, Ronald M. Krauss, Daniele Fallin, Andrew Feinberg, Devin M. Absher, Myriam Fornage, James S. Pankow, Lars Lind, Caroline Fox, Erik Ingelsson, Donna K. Arnett, Eric Boerwinkle, Liming Liang, Daniel Levy, Ian J. Deary

Editors: Cathryn Lewis