Chronic TNF exposure induces glucocorticoid‐like immunosuppression in the alveolar macrophages of aged mice that enhances their susceptibility to pneumonia

JOURNAL ARTICLE published 8 March 2024 in Aging Cell

Research funded by American Heart Association (18TPA34110195) | Division of Intramural Research, National Institute of Allergy and Infectious Diseases (AG055144)

Authors: Katherine L. Kruckow | Elizabeth Murray | Elnur Shayhidin | Alexander F. Rosenberg | Dawn M. E. Bowdish | Carlos J. Orihuela

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JOURNAL ARTICLE published March 2024 in Aging Cell

Authors: Seungman Park | Thomas C. Laskow | Jingchun Chen | Prasun Guha | Buddhadeb Dawn | Deok‐Ho Kim

Single‐worm quantitative proteomics reveals aging heterogeneity in isogenic Caenorhabditis elegans

JOURNAL ARTICLE published March 2024 in Aging Cell

Research funded by National Key Research and Development Program of China (2022YFF0608402) | National Natural Science Foundation of China (22074132,91953103,C‐0023,31972541)

Authors: Tian‐Yi Zhu | Shang‐Tong Li | Dan‐Dan Liu | Xiajun Zhang | Lianqi Zhou | Rong Zhou | Bing Yang

Microbiota‐microglia connections in age‐related cognition decline

JOURNAL ARTICLE published May 2022 in Aging Cell

Research funded by National Natural Science Foundation of China (81725009,21788102,82030049)

Authors: Rui Zhou | Shufang Qian | William C. S. Cho | Jinyun Zhou | Chentao Jin | Yan Zhong | Jing Wang | Xiaohui Zhang | Zhoujiao Xu | Mei Tian | Lawrence W. C. Chan | Hong Zhang

Ambient temperature influences aging in an annual fish (Nothobranchius rachovii)

JOURNAL ARTICLE published December 2009 in Aging Cell

Authors: Chin‐Yuan Hsu | Ya‐Chi Chiu

Mendelian randomization supports causality between overweight status and accelerated aging

JOURNAL ARTICLE published August 2023 in Aging Cell

Research funded by Chinese Academy of Medical Sciences (YS202002)

Authors: Zong Chen | Zhiyou Chen | Xiaolei Jin

Photobiomodulation suppresses JNK3 by activation of ERK/MKP7 to attenuate AMPA receptor endocytosis in Alzheimer's disease

JOURNAL ARTICLE published January 2021 in Aging Cell

Research funded by National Natural Science Foundation of China (31470072,61361160414)

Authors: Qi Shen | Lei Liu | Xiaotong Gu | Da Xing

A comprehensive AI‐driven analysis of large‐scale omic datasets reveals novel dual‐purpose targets for the treatment of cancer and aging

JOURNAL ARTICLE published December 2023 in Aging Cell

Authors: Frank W. Pun | Geoffrey Ho Duen Leung | Hoi Wing Leung | Jared Rice | Tomas Schmauck‐Medina | Sofie Lautrup | Xi Long | Bonnie Hei Man Liu | Chun Wai Wong | Ivan V. Ozerov | Alex Aliper | Feng Ren | Ari J. Rosenberg | Nishant Agrawal | Evgeny Izumchenko | Evandro F. Fang | Alex Zhavoronkov

SLC1A5 glutamine transporter is a target of MYC and mediates reduced mTORC1 signaling and increased fatty acid oxidation in long‐lived Myc hypomorphic mice

JOURNAL ARTICLE published June 2019 in Aging Cell

Research funded by National Institute on Aging (R37 AG016694,T32 AG041688)

Authors: Xiaoai Zhao | Anna P. Petrashen | Jennifer A. Sanders | Abigail L. Peterson | John M. Sedivy

Analysis of individual cells identifies cell‐to‐cell variability following induction of cellular senescence

JOURNAL ARTICLE published October 2017 in Aging Cell

Research funded by National Institutes of Health (AR063919,AG017242,AG009909)

Authors: Christopher D. Wiley | James M. Flynn | Christapher Morrissey | Ronald Lebofsky | Joe Shuga | Xiao Dong | Marc A. Unger | Jan Vijg | Simon Melov | Judith Campisi

Aging influences the cardiac macrophage phenotype and function during steady state and during inflammation

JOURNAL ARTICLE published August 2021 in Aging Cell

Research funded by National Institute of Allergy and Infectious Diseases (AI146690) | American Heart Association (AHA‐17GRNT33420101) | National Institute of Allergy and Infectious Diseases (A146252)

Authors: Noushin Saljoughian Esfahani | Qian Wu | Naresh Kumar | Latha Prabha Ganesan | William P. Lafuse | Murugesan V. S. Rajaram

Dietary restriction attenuates age‐associated muscle atrophy by lowering oxidative stress in mice even in complete absence of CuZnSOD

JOURNAL ARTICLE published October 2012 in Aging Cell

Authors: Young C. Jang | Yuhong Liu | Christopher R. Hayworth | Arunabh Bhattacharya | Michael S. Lustgarten | Florian L. Muller | Asish Chaudhuri | Wenbo Qi | Yan Li | Jing‐Yi Huang | Eric Verdin | Arlan Richardson | Holly Van Remmen

LEF1 isoforms regulate cellular senescence and aging

JOURNAL ARTICLE published December 2023 in Aging Cell

Research funded by National Heart, Lung, and Blood Institute (R01HL127349,R01HL157879,U01HL089856,U01HL089897,U01HL145550) | National Institute of General Medical Sciences (DP2GM140924) | National Institute on Alcohol Abuse and Alcoholism (R01AA028436)

Authors: Minxue Jia | Khaled Sayed | Maria G. Kapetanaki | William Dion | Lorena Rosas | Saad Irfan | Eleanor Valenzi | Ana L. Mora | Robert A. Lafyatis | Mauricio Rojas | Bokai Zhu | Panayiotis V. Benos

Phenylbutyric acid reduces amyloid plaques and rescues cognitive behavior in AD transgenic mice

JOURNAL ARTICLE published June 2011 in Aging Cell

Authors: Jesse C. Wiley | Christina Pettan-Brewer | Warren C. Ladiges

Age attenuates the transcriptional changes that occur with sleep in the medial prefrontal cortex

JOURNAL ARTICLE published December 2019 in Aging Cell

Research funded by National Institutes of Health (P01 AG017628)

Authors: Xiaofeng Guo | Brendan T. Keenan | Dimitra Sarantopoulou | Diane C. Lim | Jie Lian | Gregory R. Grant | Allan I. Pack

microRNA‐425 loss mediates amyloid plaque microenvironment heterogeneity and promotes neurodegenerative pathologies

JOURNAL ARTICLE published October 2021 in Aging Cell

Research funded by National Natural Science Foundation of China (81573401,81671043,81971068,81872841,81973297) | Natural Science Foundation of Shanghai (219ZR1431500)

Authors: Yong‐Bo Hu | Yong‐Fang Zhang | Ru‐Jing Ren | Eric B. Dammer | Xin‐Yi Xie | Shi‐Wu Chen | Qiang Huang | Wan‐Ying Huang | Rui Zhang | Hong‐Zhuan Chen | Hao Wang | Gang Wang

Nitric oxide‐soluble guanylyl cyclase pathway as a contributor to age‐related memory impairment in Drosophila

JOURNAL ARTICLE published September 2022 in Aging Cell

Research funded by Japan Agency for Medical Research and Development (JP19gm6110024) | Japan Society for the Promotion of Science (JP16H06279,JP18K19370,JP21H02621)

Authors: Ayako Tonoki | Saki Nagai | Zhihua Yu | Tong Yue | Sizhe Lyu | Xue Hou | Kotomi Onuki | Kaho Yabana | Hiroki Takahashi | Motoyuki Itoh

Myeloid cell‐specific mutation of Spi1 selectively reduces M2‐biased macrophage numbers in skeletal muscle, reduces age‐related muscle fibrosis and prevents sarcopenia

JOURNAL ARTICLE published October 2022 in Aging Cell

Research funded by National Institute of Arthritis and Musculoskeletal and Skin Diseases (R01AR054451) | National Institute on Aging (RO1AG041147)

Authors: Ying Wang | Steven S. Welc | Michelle Wehling‐Henricks | Ying Kong | Connor Thomas | Enca Montecino‐Rodriguez | Kenneth Dorshkind | James G. Tidball

Effect of aging on neurogenesis in the canine brain

JOURNAL ARTICLE published June 2008 in Aging Cell

Authors: Anton Pekcec | Wolfgang Baumgärtner | Jens P. Bankstahl | Veronika M. Stein | Heidrun Potschka

Dynamic assembly of chromatin complexes during cellular senescence: implications for the growth arrest of human melanocytic nevi

JOURNAL ARTICLE published August 2007 in Aging Cell

Authors: Debdutta Bandyopadhyay | Jonathan L. Curry | Qiushi Lin | Hunter W. Richards | Dahu Chen | Peter J. Hornsby | Nikolai A. Timchenko | Estela E. Medrano