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Myosin II Reactivation and Cytoskeletal Remodeling as a Hallmark and a Vulnerability in Melanoma Therapy Resistance

JOURNAL ARTICLE published January 2020 in Cancer Cell

Research funded by Cancer Research UK (C33043/A12065,C33043/A24478,C30122/A11527,C30122/A15774,C33043/A12065,C107/A10433,C107/A104339) | Royal Society (RG110591) | Marie Sklodowska-Curie Action (H2020-MSCA-IF-2014-EF-ST,MR/L023091/1) | CRUK (C10355/A15587) | CRUK (FC001112) | MRC (FC001112) | Wellcome Trust (FC001112) | NIHR Biomedical Research Centre (IS-BRC-1215-20006)

Authors: Jose L. Orgaz | Eva Crosas-Molist | Amine Sadok | Anna Perdrix-Rosell | Oscar Maiques | Irene Rodriguez-Hernandez | Jo Monger | Silvia Mele | Mirella Georgouli | Victoria Bridgeman | Panagiotis Karagiannis | Rebecca Lee | Pahini Pandya | Lena Boehme | Fredrik Wallberg | Chris Tape | Sophia N. Karagiannis | Ilaria Malanchi | Victoria Sanz-Moreno

https://doi.org/10.1016/j.ccell.2019.12.003 Actions

Oncogenic KRAS Regulates Amino Acid Homeostasis and Asparagine Biosynthesis via ATF4 and Alters Sensitivity to L-Asparaginase

JOURNAL ARTICLE published January 2018 in Cancer Cell

Research funded by American Cancer Society (PF-12-189-01) | National Cancer Institute (4R01CA129562,CA09302)

Authors: Dana M. Gwinn | Alex G. Lee | Marcela Briones-Martin-del-Campo | Crystal S. Conn | David R. Simpson | Anna I. Scott | Anthony Le | Tina M. Cowan | Davide Ruggero | E. Alejandro Sweet-Cordero

https://doi.org/10.1016/j.ccell.2017.12.003 Actions

Synergy between PPARγ Ligands and Platinum-Based Drugs in Cancer

JOURNAL ARTICLE published May 2007 in Cancer Cell

Authors: Geoffrey D. Girnun | Elnaz Naseri | Scott B. Vafai | Lishu Qu | Jeffrey D. Szwaya | Roderick Bronson | John A. Alberta | Bruce M. Spiegelman

https://doi.org/10.1016/j.ccr.2007.02.025 Actions

Leukemia Propagating Cells Akt Up

JOURNAL ARTICLE published March 2014 in Cancer Cell

Authors: Alejandro Gutierrez | Justine E. Roderick | Michelle A. Kelliher

https://doi.org/10.1016/j.ccr.2014.02.022 Actions

Myelodysplastic Syndromes Are Propagated by Rare and Distinct Human Cancer Stem Cells In Vivo

JOURNAL ARTICLE published April 2015 in Cancer Cell

Authors: Petter S. Woll | Una Kjällquist | Onima Chowdhury | Helen Doolittle | David C. Wedge | Supat Thongjuea | Rikard Erlandsson | Mtakai Ngara | Kristina Anderson | Qiaolin Deng | Adam J. Mead | Laura Stenson | Alice Giustacchini | Sara Duarte | Eleni Giannoulatou | Stephen Taylor | Mohsen Karimi | Christian Scharenberg | Teresa Mortera-Blanco | Iain C. Macaulay | Sally-Ann Clark | Ingunn Dybedal | Dag Josefsen | Pierre Fenaux | Peter Hokland | Mette S. Holm | Mario Cazzola | Luca Malcovati | Sudhir Tauro | David Bowen | Jacqueline Boultwood | Andrea Pellagatti | John E. Pimanda | Ashwin Unnikrishnan | Paresh Vyas | Gudrun Göhring | Brigitte Schlegelberger | Magnus Tobiasson | Gunnar Kvalheim | Stefan N. Constantinescu | Claus Nerlov | Lars Nilsson | Peter J. Campbell | Rickard Sandberg | Elli Papaemmanuil | Eva Hellström-Lindberg | Sten Linnarsson | Sten Eirik W. Jacobsen

https://doi.org/10.1016/j.ccell.2015.03.003 Actions

Spheres without Influence: Dissociating In Vitro Self-Renewal from Tumorigenic Potential in Glioma

JOURNAL ARTICLE published January 2012 in Cancer Cell

Authors: Tracy-Ann Read | Robert J. Wechsler-Reya

https://doi.org/10.1016/j.ccr.2011.12.011 Actions

A Non-canonical Polycomb Dependency in Synovial Sarcoma

JOURNAL ARTICLE published March 2018 in Cancer Cell

Authors: Joshua J. Waterfall | Paul S. Meltzer

https://doi.org/10.1016/j.ccell.2018.02.013 Actions

Genomic Analysis Drives Tailored Therapy in Poor Risk Childhood Leukemia

JOURNAL ARTICLE published August 2012 in Cancer Cell

Authors: Christine J. Harrison

https://doi.org/10.1016/j.ccr.2012.07.012 Actions

Not So Fast: Cultivating miRs as Kinks in the Chain of the Cell Cycle

JOURNAL ARTICLE published April 2017 in Cancer Cell

Authors: Matthew J. Schiewer | Karen E. Knudsen

https://doi.org/10.1016/j.ccell.2017.03.012 Actions

Spying on cancer

JOURNAL ARTICLE published January 2005 in Cancer Cell

Authors: Shimon Gross | David Piwnica-Worms

https://doi.org/10.1016/j.ccr.2004.12.011 Actions

Dietary modulation of the gut microbiome as an immunoregulatory intervention

JOURNAL ARTICLE published March 2022 in Cancer Cell

Authors: Vyara Matson | Thomas F. Gajewski

https://doi.org/10.1016/j.ccell.2022.02.014 Actions

Inactivation of E2F3 results in centrosome amplification

JOURNAL ARTICLE published April 2003 in Cancer Cell

Authors: Harold I Saavedra | Baidehi Maiti | Cynthia Timmers | Rachel Altura | Yukari Tokuyama | Kenji Fukasawa | Gustavo Leone

https://doi.org/10.1016/s1535-6108(03)00083-7 Actions

The Two Faces of NF-κB Signaling in Cancer Development and Therapy

JOURNAL ARTICLE published November 2011 in Cancer Cell

Authors: Ulf Klein | Sankar Ghosh

https://doi.org/10.1016/j.ccr.2011.10.026 Actions

To the Rescue: The Fanconi Anemia Genome Stability Pathway Salvages Replication Forks

JOURNAL ARTICLE published July 2012 in Cancer Cell

Authors: George-Lucian Moldovan | Alan D. D'Andrea

https://doi.org/10.1016/j.ccr.2012.06.006 Actions

mTORC1 gRABs the Golgi

JOURNAL ARTICLE published November 2014 in Cancer Cell

Authors: Joan Sanchez-Gurmaches | David A. Guertin

https://doi.org/10.1016/j.ccell.2014.10.011 Actions

SnapShot: Melanoma

JOURNAL ARTICLE published May 2013 in Cancer Cell

Authors: Adina Vultur | Meenhard Herlyn

https://doi.org/10.1016/j.ccr.2013.05.001 Actions

Developing and validating model systems for immuno-oncology

JOURNAL ARTICLE published August 2021 in Cancer Cell

Research funded by National Cancer Institute (5 R01 CA219880,P30 CA034196)

Authors: Claire E. McCarthy | Nastaran Zahir | Mariam Eljanne | Elad Sharon | Emile E. Voest | Karolina Palucka

https://doi.org/10.1016/j.ccell.2021.05.017 Actions

Venetoclax Adds a New Arrow Targeting Relapsed CLL to the Quiver

JOURNAL ARTICLE published January 2016 in Cancer Cell

Research funded by National Cancer Institute (P01 CA095426,T32 CA09338,K23 CA178183,R35 CA197734,R01 CA169162,R01 CA177292)

Authors: Kerry A. Rogers | John C. Byrd

https://doi.org/10.1016/j.ccell.2015.12.010 Actions

No T without D3

JOURNAL ARTICLE published December 2003 in Cancer Cell

Authors: Andrew P Weng | Jon C Aster

https://doi.org/10.1016/s1535-6108(03)00305-2 Actions

Taking the Stress out of Melanoma

JOURNAL ARTICLE published March 2009 in Cancer Cell

Authors: Matthew J. Martin | David Carling | Richard Marais

https://doi.org/10.1016/j.ccr.2009.02.006 Actions
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