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Bi-allelic Loss of CDKN2A Initiates Melanoma Invasion via BRN2 Activation

JOURNAL ARTICLE published July 2018 in Cancer Cell

Research funded by NIH (DP5OD019787,5T32 CA177555) | Melanoma Research Alliance (400991) | NCI (1R35CA220481)

Authors: Hanlin Zeng | Aparna Jorapur | A. Hunter Shain | Ursula E. Lang | Rodrigo Torres | Yuntian Zhang | Andrew S. McNeal | Thomas Botton | Jue Lin | Matthew Donne | Ingmar N. Bastian | Richard Yu | Jeffrey P. North | Laura Pincus | Beth S. Ruben | Nancy M. Joseph | Iwei Yeh | Boris C. Bastian | Robert L. Judson

https://doi.org/10.1016/j.ccell.2018.05.014 Actions

Immunogenomic Landscape of Hematological Malignancies

JOURNAL ARTICLE published September 2020 in Cancer Cell

Authors: Olli Dufva | Petri Pölönen | Oscar Brück | Mikko A.I. Keränen | Jay Klievink | Juha Mehtonen | Jani Huuhtanen | Ashwini Kumar | Disha Malani | Sanna Siitonen | Matti Kankainen | Bishwa Ghimire | Jenni Lahtela | Pirkko Mattila | Markus Vähä-Koskela | Krister Wennerberg | Kirsi Granberg | Suvi-Katri Leivonen | Leo Meriranta | Caroline Heckman | Sirpa Leppä | Matti Nykter | Olli Lohi | Merja Heinäniemi | Satu Mustjoki

https://doi.org/10.1016/j.ccell.2020.06.002 Actions

Functional Heterogeneity of Genetically Defined Subclones in Acute Myeloid Leukemia

JOURNAL ARTICLE published March 2014 in Cancer Cell

Authors: Jeffery M. Klco | David H. Spencer | Christopher A. Miller | Malachi Griffith | Tamara L. Lamprecht | Michelle O’Laughlin | Catrina Fronick | Vincent Magrini | Ryan T. Demeter | Robert S. Fulton | William C. Eades | Daniel C. Link | Timothy A. Graubert | Matthew J. Walter | Elaine R. Mardis | John F. Dipersio | Richard K. Wilson | Timothy J. Ley

https://doi.org/10.1016/j.ccr.2014.01.031 Actions

Intraclonal Plasticity in Mammary Tumors Revealed through Large-Scale Single-Cell Resolution 3D Imaging

JOURNAL ARTICLE published June 2019 in Cancer Cell

Authors: Anne C. Rios | Bianca D. Capaldo | François Vaillant | Bhupinder Pal | Ravian van Ineveld | Caleb A. Dawson | Yunshun Chen | Emma Nolan | Nai Yang Fu | Felicity C. Jackling | Sapna Devi | David Clouston | Lachlan Whitehead | Gordon K. Smyth | Scott N. Mueller | Geoffrey J. Lindeman | Jane E. Visvader

https://doi.org/10.1016/j.ccell.2019.05.011 Actions

The roles of ferroptosis in cancer: Tumor suppression, tumor microenvironment, and therapeutic interventions

JOURNAL ARTICLE published April 2024 in Cancer Cell

Authors: Guang Lei | Li Zhuang | Boyi Gan

https://doi.org/10.1016/j.ccell.2024.03.011 Actions

Genetic interactions reveal distinct biological and therapeutic implications in breast cancer

JOURNAL ARTICLE published April 2024 in Cancer Cell

Authors: Cai-Jin Lin | Xi Jin | Ding Ma | Chao Chen | Yang Ou-Yang | Yu-Chen Pei | Chao-Zheng Zhou | Fei-Lin Qu | Yun-Jin Wang | Cheng-Lin Liu | Lei Fan | Xin Hu | Zhi-Ming Shao | Yi-Zhou Jiang

https://doi.org/10.1016/j.ccell.2024.03.006 Actions

Targeting APOBECs in cancer: It’s about timing

JOURNAL ARTICLE published April 2024 in Cancer Cell

Research funded by NIH (R01 CA249291,P50 CA265826)

Authors: Aaron N. Hata | Mani Larijani

https://doi.org/10.1016/j.ccell.2024.03.010 Actions

Tumor Cells Require Thymidylate Kinase to Prevent dUTP Incorporation during DNA Repair

JOURNAL ARTICLE published July 2012 in Cancer Cell

Research funded by National Science Council (100-2325-B-010-001)

Authors: Chun-Mei Hu | Ming-Tyng Yeh | Ning Tsao | Chih-Wei Chen | Quan-Ze Gao | Chia-Yun Chang | Ming-Hsiang Lee | Jim-Min Fang | Sheh-Yi Sheu | Chow-Jaw Lin | Mei-Chun Tseng | Yu-Ju Chen | Zee-Fen Chang

https://doi.org/10.1016/j.ccr.2012.04.038 Actions

Bacteria and fungi: The counteracting modulators of immune responses to radiation therapy in cancer

JOURNAL ARTICLE published September 2021 in Cancer Cell

Authors: Erick Riquelme | Florencia McAllister

https://doi.org/10.1016/j.ccell.2021.08.004 Actions

PML-RARα/RXR Alters the Epigenetic Landscape in Acute Promyelocytic Leukemia

JOURNAL ARTICLE published February 2010 in Cancer Cell

Authors: Joost H.A. Martens | Arie B. Brinkman | Femke Simmer | Kees-Jan Francoijs | Angela Nebbioso | Felicetto Ferrara | Lucia Altucci | Hendrik G. Stunnenberg

https://doi.org/10.1016/j.ccr.2009.12.042 Actions

Hepatic RIG-I Predicts Survival and Interferon-α Therapeutic Response in Hepatocellular Carcinoma

JOURNAL ARTICLE published January 2014 in Cancer Cell

Authors: Jin Hou | Ye Zhou | Yuanyuan Zheng | Jia Fan | Weiping Zhou | Irene O.L. Ng | Huichuan Sun | Lunxiu Qin | Shuangjian Qiu | Joyce M.F. Lee | Chung-Mau Lo | Kwan Man | Yuan Yang | Yun Yang | Yingyun Yang | Qian Zhang | Xuhui Zhu | Nan Li | Zhengxin Wang | Guoshan Ding | Shi-Mei Zhuang | Limin Zheng | Xiaoling Luo | Yuan Xie | Anmin Liang | Zhugang Wang | Ming Zhang | Qiang Xia | Tingbo Liang | Yizhi Yu | Xuetao Cao

https://doi.org/10.1016/j.ccr.2013.11.011 Actions

Truncating Erythropoietin Receptor Rearrangements in Acute Lymphoblastic Leukemia

JOURNAL ARTICLE published February 2016 in Cancer Cell

Research funded by National Cancer Institute (CA21765,U01 CA157937,U24 CA114737,U10 CA180820,CA180827,U10 CA101140,CA145707,U10 CA98543,U10 CA98413,U24 CA114766)

Authors: Ilaria Iacobucci | Yongjin Li | Kathryn G. Roberts | Stephanie M. Dobson | Jaeseung C. Kim | Debbie Payne-Turner | Richard C. Harvey | Marcus Valentine | Kelly McCastlain | John Easton | Donald Yergeau | Laura J. Janke | Ying Shao | I-Ming L. Chen | Michael Rusch | Sasan Zandi | Steven M. Kornblau | Marina Konopleva | Elias Jabbour | Elisabeth M. Paietta | Jacob M. Rowe | Ching-Hon Pui | Julie Gastier-Foster | Zhaohui Gu | Shalini Reshmi | Mignon L. Loh | Janis Racevskis | Martin S. Tallman | Peter H. Wiernik | Mark R. Litzow | Cheryl L. Willman | John D. McPherson | James R. Downing | Jinghui Zhang | John E. Dick | Stephen P. Hunger | Charles G. Mullighan

https://doi.org/10.1016/j.ccell.2015.12.013 Actions

Benchmarking mismatch repair testing for patients with cancer receiving immunotherapy

JOURNAL ARTICLE published February 2024 in Cancer Cell

Authors: Elias Bou Farhat | Elio Adib | Melissa Daou | Abdul Rafeh Naqash | Ursula Matulonis | Kimmie Ng | David J. Kwiatkowski | Lynette M. Sholl | Amin H. Nassar

https://doi.org/10.1016/j.ccell.2024.01.009 Actions

Non-conventional Inhibitory CD4+Foxp3–PD-1hi T Cells as a Biomarker of Immune Checkpoint Blockade Activity

JOURNAL ARTICLE published October 2018 in Cancer Cell

Authors: Roberta Zappasodi | Sadna Budhu | Matthew D. Hellmann | Michael A. Postow | Yasin Senbabaoglu | Sasikanth Manne | Billel Gasmi | Cailian Liu | Hong Zhong | Yanyun Li | Alexander C. Huang | Daniel Hirschhorn-Cymerman | Katherine S. Panageas | E. John Wherry | Taha Merghoub | Jedd D. Wolchok

https://doi.org/10.1016/j.ccell.2018.09.007 Actions

Copy Number Gain of hsa-miR-569 at 3q26.2 Leads to Loss of TP53INP1 and Aggressiveness of Epithelial Cancers

JOURNAL ARTICLE published December 2014 in Cancer Cell

Authors: Pradeep Chaluvally-Raghavan | Fan Zhang | Sunila Pradeep | Mark P. Hamilton | Xi Zhao | Rajesha Rupaimoole | Tyler Moss | Yiling Lu | Shuangxing Yu | Chad V. Pecot | Miriam R. Aure | Sylvain Peuget | Cristian Rodriguez-Aguayo | Hee-Dong Han | Dong Zhang | Avinashnarayan Venkatanarayan | Marit Krohn | Vessela N. Kristensen | Mihai Gagea | Prahlad Ram | Wenbin Liu | Gabriel Lopez-Berestein | Philip L. Lorenzi | Anne-Lise Børresen-Dale | Koei Chin | Joe Gray | Nelson J. Dusetti | Sean E. McGuire | Elsa R. Flores | Anil K. Sood | Gordon B. Mills

https://doi.org/10.1016/j.ccell.2014.10.010 Actions

Met decoys

JOURNAL ARTICLE published July 2004 in Cancer Cell

Authors: Yu-Wen Zhang | Carrie Graveel | Nariyoshi Shinomiya | George F.Vande Woude

https://doi.org/10.1016/j.ccr.2004.07.003 Actions

From intestinal metaplasia to gastric cancer: Witnessing the rise of evil over time and space

JOURNAL ARTICLE published December 2023 in Cancer Cell

Research funded by National Natural Science Foundation of China (U22A20327) | National Key Research and Development Program of China (2022YFC2505006)

Authors: Cheng Zhang | Xi Jiao | Lin Shen

https://doi.org/10.1016/j.ccell.2023.10.005 Actions

DOTting the Path to Doom: How Acceleration of Histone Methylation Leads to Leukemia

JOURNAL ARTICLE published December 2014 in Cancer Cell

Authors: Christian Bach | Robert K. Slany

https://doi.org/10.1016/j.ccell.2014.11.004 Actions

MLL-AF9 Leukemia Stem Cells: Hardwired or Taking Cues from the Microenvironment?

JOURNAL ARTICLE published June 2008 in Cancer Cell

Authors: Andrew G. Muntean | Jay L. Hess

https://doi.org/10.1016/j.ccr.2008.05.012 Actions

Changes in Treatment Behavior during the COVID-19 Pandemic among Patients at a Cancer Hospital

JOURNAL ARTICLE published February 2021 in Cancer Cell

Authors: Yasuyoshi Sato | Yu Fujiwara | Naoki Fukuda | Brian Hayama | Yoshinori Ito | Shinji Ohno | Shunji Takahashi

https://doi.org/10.1016/j.ccell.2021.01.002 Actions
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