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Mitogen requirement for cell cycle progression in the absence of pocket protein activity

JOURNAL ARTICLE published December 2005 in Cancer Cell

Authors: Floris Foijer | Rob M.F. Wolthuis | Valerie Doodeman | René H. Medema | Hein te Riele

https://doi.org/10.1016/j.ccr.2005.10.021 Actions

Oncogenic KRAS Regulates Amino Acid Homeostasis and Asparagine Biosynthesis via ATF4 and Alters Sensitivity to L-Asparaginase

JOURNAL ARTICLE published January 2018 in Cancer Cell

Research funded by American Cancer Society (PF-12-189-01) | National Cancer Institute (4R01CA129562,CA09302)

Authors: Dana M. Gwinn | Alex G. Lee | Marcela Briones-Martin-del-Campo | Crystal S. Conn | David R. Simpson | Anna I. Scott | Anthony Le | Tina M. Cowan | Davide Ruggero | E. Alejandro Sweet-Cordero

https://doi.org/10.1016/j.ccell.2017.12.003 Actions

Location, Location, Location: FoxM1 Mediates β-Catenin Nuclear Translocation and Promotes Glioma Tumorigenesis

JOURNAL ARTICLE published October 2011 in Cancer Cell

Authors: Angela Bowman | Roel Nusse

https://doi.org/10.1016/j.ccr.2011.10.003 Actions

Activation of translation complex eIF4F is essential for the genesis and maintenance of the malignant phenotype in human mammary epithelial cells

JOURNAL ARTICLE published June 2004 in Cancer Cell

Authors: Svetlana Avdulov | Shunan Li | David Burrichter | Mark Peterson | David M Perlman | J.Carlos Manivel | Nahum Sonenberg | Douglas Yee | Peter B Bitterman | Vitaly A Polunovsky

https://doi.org/10.1016/j.ccr.2004.05.024 Actions

Combined Genetic Inactivation of β2-Microglobulin and CD58 Reveals Frequent Escape from Immune Recognition in Diffuse Large B Cell Lymphoma

JOURNAL ARTICLE published December 2011 in Cancer Cell

Authors: Madhavi Challa-Malladi | Yen K. Lieu | Olivia Califano | Antony B. Holmes | Govind Bhagat | Vundavalli V. Murty | David Dominguez-Sola | Laura Pasqualucci | Riccardo Dalla-Favera

https://doi.org/10.1016/j.ccr.2011.11.006 Actions

Distinct effects on gene expression of chemical and genetic manipulation of the cancer epigenome revealed by a multimodality approach

JOURNAL ARTICLE published October 2004 in Cancer Cell

Authors: David Gius | Hengmi Cui | C.Matthew Bradbury | John Cook | DeeDee K. Smart | Shuping Zhao | Lynn Young | Sheri A. Brandenburg | Yali Hu | Kheem S. Bisht | Allen S. Ho | David Mattson | Lunching Sun | Peter J. Munson | Eric Y. Chuang | James B. Mitchell | Andrew P. Feinberg

https://doi.org/10.1016/j.ccr.2004.08.029 Actions

CREPT Accelerates Tumorigenesis by Regulating the Transcription of Cell-Cycle-Related Genes

JOURNAL ARTICLE published January 2012 in Cancer Cell

Authors: Dongdong Lu | Yinyuan Wu | Yinyin Wang | Fangli Ren | Dianjun Wang | Fuqin Su | Yanquan Zhang | Xi Yang | Guihua Jin | Xinbao Hao | Dacheng He | Yonggong Zhai | David M. Irwin | Jim Hu | Joseph J.Y. Sung | Jun Yu | Baoqing Jia | Zhijie Chang

https://doi.org/10.1016/j.ccr.2011.12.016 Actions

Critical role for Gab2 in transformation by BCR/ABL

JOURNAL ARTICLE published June 2002 in Cancer Cell

Authors: Martin Sattler | M.Golam Mohi | Yuri B Pride | Laura R Quinnan | Nicole A Malouf | Klaus Podar | Franck Gesbert | Hiromi Iwasaki | Shaoguang Li | Richard A Van Etten | Haihua Gu | James D Griffin | Benjamin G Neel

https://doi.org/10.1016/s1535-6108(02)00074-0 Actions

Redefining breast cancer subtypes to guide treatment prioritization and maximize response: Predictive biomarkers across 10 cancer therapies

JOURNAL ARTICLE published June 2022 in Cancer Cell

Authors: Denise M. Wolf | Christina Yau | Julia Wulfkuhle | Lamorna Brown-Swigart | Rosa I. Gallagher | Pei Rong Evelyn Lee | Zelos Zhu | Mark J. Magbanua | Rosalyn Sayaman | Nicholas O’Grady | Amrita Basu | Amy Delson | Jean Philippe Coppé | Ruixiao Lu | Jerome Braun | Smita M. Asare | Laura Sit | Jeffrey B. Matthews | Jane Perlmutter | Nola Hylton | Minetta C. Liu | Paula Pohlmann | W. Fraser Symmans | Hope S. Rugo | Claudine Isaacs | Angela M. DeMichele | Douglas Yee | Donald A. Berry | Lajos Pusztai | Emanuel F. Petricoin | Gillian L. Hirst | Laura J. Esserman | Laura J. van 't Veer

https://doi.org/10.1016/j.ccell.2022.05.005 Actions

Durvalumab with olaparib and paclitaxel for high-risk HER2-negative stage II/III breast cancer: Results from the adaptively randomized I-SPY2 trial

JOURNAL ARTICLE published July 2021 in Cancer Cell

Authors: Lajos Pusztai | Christina Yau | Denise M. Wolf | Hyo S. Han | Lili Du | Anne M. Wallace | Erica String-Reasor | Judy C. Boughey | A. Jo Chien | Anthony D. Elias | Heather Beckwith | Rita Nanda | Kathy S. Albain | Amy S. Clark | Kathleen Kemmer | Kevin Kalinsky | Claudine Isaacs | Alexandra Thomas | Rebecca Shatsky | Theresa L. Helsten | Andres Forero-Torres | Minetta C. Liu | Lamorna Brown-Swigart | Emmanuel F. Petricoin | Julia D. Wulfkuhle | Smita M. Asare | Amy Wilson | Ruby Singhrao | Laura Sit | Gillian L. Hirst | Scott Berry | Ashish Sanil | Adam L. Asare | Jeffrey B. Matthews | Jane Perlmutter | Michelle Melisko | Hope S. Rugo | Richard B. Schwab | W. Fraser Symmans | Doug Yee | Laura J. van’t Veer | Nola M. Hylton | Angela M. DeMichele | Donald A. Berry | Laura J. Esserman

https://doi.org/10.1016/j.ccell.2021.05.009 Actions

COVID-19 mRNA booster vaccines elicit strong protection against SARS-CoV-2 Omicron variant in patients with cancer

JOURNAL ARTICLE published February 2022 in Cancer Cell

Authors: Cong Zeng | John P. Evans | Karthik Chakravarthy | Panke Qu | Sarah Reisinger | No-Joon Song | Mark P. Rubinstein | Peter G. Shields | Zihai Li | Shan-Lu Liu

https://doi.org/10.1016/j.ccell.2021.12.014 Actions

STAG2 loss rewires oncogenic and developmental programs to promote metastasis in Ewing sarcoma

JOURNAL ARTICLE published June 2021 in Cancer Cell

Authors: Biniam Adane | Gabriela Alexe | Bo Kyung A. Seong | Diana Lu | Elizabeth E. Hwang | Denes Hnisz | Caleb A. Lareau | Linda Ross | Shan Lin | Filemon S. Dela Cruz | Melissa Richardson | Abraham S. Weintraub | Sarah Wang | Amanda Balboni Iniguez | Neekesh V. Dharia | Amy Saur Conway | Amanda L. Robichaud | Benjamin Tanenbaum | John M. Krill-Burger | Francisca Vazquez | Monica Schenone | Jason N. Berman | Andrew L. Kung | Steven A. Carr | Martin J. Aryee | Richard A. Young | Brian D. Crompton | Kimberly Stegmaier

https://doi.org/10.1016/j.ccell.2021.05.007 Actions

New Views into the Genetic Landscape of Metastatic Breast Cancer

JOURNAL ARTICLE published August 2017 in Cancer Cell

Authors: Xiaoyu Zhao | Scott Powers

https://doi.org/10.1016/j.ccell.2017.07.011 Actions

The crosstalk between macrophages and cancer cells potentiates pancreatic cancer cachexia

JOURNAL ARTICLE published April 2024 in Cancer Cell

Research funded by National Institutes of Health (R01 CA203108,R01 CA247234,P30 CA225520,R01 CA186338)

Authors: Mingyang Liu | Yu Ren | Zhijun Zhou | Jingxuan Yang | Xiuhui Shi | Yang Cai | Alex X. Arreola | Wenyi Luo | Kar-Ming Fung | Chao Xu | Ryan D. Nipp | Michael S. Bronze | Lei Zheng | Yi-Ping Li | Courtney W. Houchen | Yuqing Zhang | Min Li

https://doi.org/10.1016/j.ccell.2024.03.009 Actions

Myosin II Reactivation and Cytoskeletal Remodeling as a Hallmark and a Vulnerability in Melanoma Therapy Resistance

JOURNAL ARTICLE published January 2020 in Cancer Cell

Research funded by Cancer Research UK (C33043/A12065,C33043/A24478,C30122/A11527,C30122/A15774,C33043/A12065,C107/A10433,C107/A104339) | Royal Society (RG110591) | Marie Sklodowska-Curie Action (H2020-MSCA-IF-2014-EF-ST,MR/L023091/1) | CRUK (C10355/A15587) | CRUK (FC001112) | MRC (FC001112) | Wellcome Trust (FC001112) | NIHR Biomedical Research Centre (IS-BRC-1215-20006)

Authors: Jose L. Orgaz | Eva Crosas-Molist | Amine Sadok | Anna Perdrix-Rosell | Oscar Maiques | Irene Rodriguez-Hernandez | Jo Monger | Silvia Mele | Mirella Georgouli | Victoria Bridgeman | Panagiotis Karagiannis | Rebecca Lee | Pahini Pandya | Lena Boehme | Fredrik Wallberg | Chris Tape | Sophia N. Karagiannis | Ilaria Malanchi | Victoria Sanz-Moreno

https://doi.org/10.1016/j.ccell.2019.12.003 Actions

Synergy between PPARγ Ligands and Platinum-Based Drugs in Cancer

JOURNAL ARTICLE published May 2007 in Cancer Cell

Authors: Geoffrey D. Girnun | Elnaz Naseri | Scott B. Vafai | Lishu Qu | Jeffrey D. Szwaya | Roderick Bronson | John A. Alberta | Bruce M. Spiegelman

https://doi.org/10.1016/j.ccr.2007.02.025 Actions

Undifferentiated Sarcomas Develop through Distinct Evolutionary Pathways

JOURNAL ARTICLE published March 2019 in Cancer Cell

Research funded by BBSRC (BB/R009295/1) | PCUK (MA-TR15-009) | Medical Research Council (MR/M025411/1) | Wellcome Trust (FC001202) | Medical Research Council (FC001202)

Authors: Christopher D. Steele | Maxime Tarabichi | Dahmane Oukrif | Amy P. Webster | Hongtao Ye | Matthew Fittall | Patrick Lombard | Iñigo Martincorena | Patrick S. Tarpey | Grace Collord | Kerstin Haase | Sandra J. Strauss | Fitim Berisha | Heli Vaikkinen | Pawan Dhami | Marnix Jansen | Sam Behjati | M. Fernanda Amary | Roberto Tirabosco | Andrew Feber | Peter J. Campbell | Ludmil B. Alexandrov | Peter Van Loo | Adrienne M. Flanagan | Nischalan Pillay

https://doi.org/10.1016/j.ccell.2019.02.002 Actions

A signaling pathway leading to metastasis is controlled by N-cadherin and the FGF receptor

JOURNAL ARTICLE published October 2002 in Cancer Cell

Authors: Kimita Suyama | Irina Shapiro | Mitchell Guttman | Rachel B. Hazan

https://doi.org/10.1016/s1535-6108(02)00150-2 Actions

A Murine Model of Chronic Lymphocytic Leukemia Based on B Cell-Restricted Expression of Sf3b1 Mutation and Atm Deletion

JOURNAL ARTICLE published February 2019 in Cancer Cell

Research funded by NCI (1R01 CA21673-01,1R01 CA155010-01A1,1U10 CA180861-01) | NHLBI (1R01 HL103532-01,1R01 HL116452-01,ZIA HL002346-13) | NIH (R01 DK087992,P01 CA81534,5P30 CA006516,R35 GM122524) | US Public Health Service (R01 CA63113,R01 CA173023,P01 CA203655) | National Science Foundation (DGE1144152)

Authors: Shanye Yin | Rutendo G. Gambe | Jing Sun | Aina Zurita Martinez | Zachary J. Cartun | Fara Faye D. Regis | Youzhong Wan | Jean Fan | Angela N. Brooks | Sarah E.M. Herman | Elisa ten Hacken | Amaro Taylor-Weiner | Laura Z. Rassenti | Emanuela M. Ghia | Thomas J. Kipps | Esther A. Obeng | Carrie L. Cibulskis | Donna Neuberg | Dean R. Campagna | Mark D. Fleming | Benjamin L. Ebert | Adrian Wiestner | Ignaty Leshchiner | James A. DeCaprio | Gad Getz | Robin Reed | Ruben D. Carrasco | Catherine J. Wu | Lili Wang

https://doi.org/10.1016/j.ccell.2018.12.013 Actions

CDK 4/6 Inhibitors Sensitize PIK3CA Mutant Breast Cancer to PI3K Inhibitors

JOURNAL ARTICLE published July 2014 in Cancer Cell

Authors: Sadhna R. Vora | Dejan Juric | Nayoon Kim | Mari Mino-Kenudson | Tiffany Huynh | Carlotta Costa | Elizabeth L. Lockerman | Sarah F. Pollack | Manway Liu | Xiaoyan Li | Joseph Lehar | Marion Wiesmann | Markus Wartmann | Yan Chen | Z. Alexander Cao | Maria Pinzon-Ortiz | Sunkyu Kim | Robert Schlegel | Alan Huang | Jeffrey A. Engelman

https://doi.org/10.1016/j.ccr.2014.05.020 Actions
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