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Showing results for ISSN matching 1543-8384

Porphyrin-Loaded TyroSpheres for the Intracellular Delivery of Drugs and Photoinduced Oxidant Species

JOURNAL ARTICLE published 3 August 2020 in Molecular Pharmaceutics

Research funded by Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico (303831/2019-7) | Funda??o de Amparo ? Pesquisa do Estado de S?o Paulo (2013/07937-8,2013/16532-1)

Authors: Tayana Mazin Tsubone | Zheng Zhang | Ritu Goyal | Carolina Santacruz | Waleska Kerllen Martins | Joachim Kohn | Mauricio S. Baptista

https://doi.org/10.1021/acs.molpharmaceut.0c00338 Actions

Intrinsic Dynamics of DNA–Polymer Complexes: A Mechanism for DNA Release

JOURNAL ARTICLE published 4 September 2012 in Molecular Pharmaceutics

Authors: Lisa E. Prevette | Evgenia N. Nikolova | Hashim M. Al-Hashimi | Mark M. Banaszak Holl

https://doi.org/10.1021/mp3002864 Actions

Developing an Anticancer Copper(II) Multitarget Pro-Drug Based on the His146 Residue in the IB Subdomain of Modified Human Serum Albumin

JOURNAL ARTICLE published 4 June 2018 in Molecular Pharmaceutics

Research funded by Ministry of Education of the People's Republic of China (CMEMR2017-A03,IRT-16R15) | Natural Science Foundation of Guangxi Province (AD17129007,2017GXNSFEA198002) | National Natural Science Foundation of China (21431001,31460232)

Authors: Jun Wang | Yi Gou | Zhenlei Zhang | Ping Yu | Jinxu Qi | Qipin Qin | Hongbin Sun | Xiaoyang Wu | Hong Liang | Feng Yang

https://doi.org/10.1021/acs.molpharmaceut.8b00045 Actions

Physiologically Based Biopharmaceutics Modeling (PBBM): Best Practices for Drug Product Quality, Regulatory and Industry Perspectives: 2023 Workshop Summary Report

JOURNAL ARTICLE published 10 April 2024 in Molecular Pharmaceutics

Research funded by U.S. Food and Drug Administration (5U01FD005946)

Authors: Claire Mackie | Sumit Arora | Paul Seo | Rebecca Moody | Bhagwant Rege | Xavier Pepin | Tycho Heimbach | Christer Tannergren | Amitava Mitra | Sandra Suarez-Sharp | Luiza Novaes Borges | Shinichi Kijima | Evangelos Kotzagiorgis | Maria Malamatari | Shereeni Veerasingham | James E. Polli | Gregory Rullo

https://doi.org/10.1021/acs.molpharmaceut.4c00202 Actions

Evaluation of Cellular Uptake and Gene Transfer Efficiency of Pegylated Poly-l-lysine Compacted DNA:  Implications for Cancer Gene Therapy

JOURNAL ARTICLE published 1 December 2006 in Molecular Pharmaceutics

Authors: M. Walsh | M. Tangney | M. J. O'Neill | J. O. Larkin | D. M. Soden | S. L. McKenna | R. Darcy | G. C. O'Sullivan | C. M. O'Driscoll

https://doi.org/10.1021/mp0600034 Actions

Photodisruption of the Structurally Conserved Cys-Cys-Trp Triads Leads to Reduction-Resistant Scrambled Intrachain Disulfides in an IgG1 Monoclonal Antibody

JOURNAL ARTICLE published 2 April 2018 in Molecular Pharmaceutics

Authors: Aaron T. Wecksler | Jian Yin | Paula Lee Tao | Bruce Kabakoff | Alavattam Sreedhara | Galahad Deperalta

https://doi.org/10.1021/acs.molpharmaceut.7b01128 Actions

Relevance of Biophysical Interactions of Nanoparticles with a Model Membrane in Predicting Cellular Uptake: Study with TAT Peptide-Conjugated Nanoparticles

JOURNAL ARTICLE published 5 October 2009 in Molecular Pharmaceutics

Authors: Chiranjeevi Peetla | Kavitha S. Rao | Vinod Labhasetwar

https://doi.org/10.1021/mp900011h Actions

Live Cells versus Fixated Cells: Kinetic Measurements of Biomolecular Interactions with the LigandTracer Method and Surface Plasmon Resonance Microscopy

JOURNAL ARTICLE published 3 April 2023 in Molecular Pharmaceutics

Research funded by National Natural Science Foundation of China (21802051,21906065)

Authors: Tianbao Dong | Chaowei Han | Xin Liu | Zhichao Wang | Yanhui Wang | Qing Kang | Pengcheng Wang | Feimeng Zhou

https://doi.org/10.1021/acs.molpharmaceut.2c01047 Actions

Investigation on the Interaction of Dabrafenib with Human Serum Albumin Using Combined Experiment and Molecular Dynamics Simulation: Exploring the Binding Mechanism, Esterase-like Activity, and Antioxidant Activity

JOURNAL ARTICLE published 3 December 2018 in Molecular Pharmaceutics

Research funded by Ministry of Education of the People's Republic of China (2018SCU12043) | National Natural Science Foundation of China (21808020) | Sichuan Province (2018JY0188,2018JY0151)

Authors: Zili Suo | Xinnuo Xiong | Qiaomei Sun | Ludan Zhao | Peixiao Tang | Quan Hou | Yongkui Zhang | Di Wu | Hui Li

https://doi.org/10.1021/acs.molpharmaceut.8b00806 Actions

Evaluating the Utility of Canine Mdr1 Knockout Madin-Darby Canine Kidney I Cells in Permeability Screening and Efflux Substrate Determination

JOURNAL ARTICLE published 5 November 2018 in Molecular Pharmaceutics

Authors: Eugene C. Chen | Fabio Broccatelli | Emile Plise | Buyun Chen | Liling Liu | Jonathan Cheong | Shu Zhang | Jamie Jorski | Katherine Gaffney | Kayla K. Umemoto | Laurent Salphati

https://doi.org/10.1021/acs.molpharmaceut.8b00688 Actions

Long-Acting Nanohybrid Hydrogel Induces Persistent Immunogenic Chemotherapy for Suppressing Postoperative Tumor Recurrence and Metastasis

JOURNAL ARTICLE published 4 December 2023 in Molecular Pharmaceutics

Research funded by Jiangsu Provincial Key Research and Development Program (BE2022724) | National Key Research and Development Program of China (2022YFA1206000) | Science and Technology Program of Suzhou (SYS2020083) | National Natural Science Foundation of China (31500811,81703512,52125304,51873143)

Authors: Yaoqi Li | Jie Zhu | Yifan Yang | Yitian Chen | Lishan Liu | Jing Tao | Huabing Chen | Yibin Deng

https://doi.org/10.1021/acs.molpharmaceut.3c00746 Actions

AVN-211, Novel and Highly Selective 5-HT6 Receptor Small Molecule Antagonist, for the Treatment of Alzheimer’s Disease

JOURNAL ARTICLE published 7 March 2016 in Molecular Pharmaceutics

Authors: Alexandre V. Ivachtchenko | Yan Lavrovsky | Yan A. Ivanenkov

https://doi.org/10.1021/acs.molpharmaceut.5b00830 Actions

Chalcone Based Homodimeric PET Agent, 11C-(Chal)2DEA-Me, for Beta Amyloid Imaging: Synthesis and Bioevaluation

JOURNAL ARTICLE published 2 April 2018 in Molecular Pharmaceutics

Research funded by Defence Research and Development Organisation (TD-16-17/INM-321)

Authors: Kanchan Chauhan | Anjani K. Tiwari | Nidhi Chadha | Ankur Kaul | Ajai Kumar Singh | Anupama Datta

https://doi.org/10.1021/acs.molpharmaceut.7b01070 Actions

In Vitro Predictive Dissolution Test Should Be Developed and Recommended as a Bioequivalence Standard for the Immediate-Release Solid Oral Dosage Forms of the Highly Variable Mycophenolate Mofetil

JOURNAL ARTICLE published 4 July 2022 in Molecular Pharmaceutics

Authors: Kai Wang | Yangbing Li | Bing Chen | Hao Chen | David E. Smith | Duxin Sun | Meihua R. Feng | Gordon L. Amidon

https://doi.org/10.1021/acs.molpharmaceut.1c00792 Actions

Potentiating Antigen Specific Immune Response by Targeted Delivery of the PLGA-Based Model Cancer Vaccine

JOURNAL ARTICLE published 4 February 2019 in Molecular Pharmaceutics

Research funded by Natural Sciences and Engineering Research Council of Canada (RGPIN 402581-201)

Authors: Sheikh Tasnim Jahan | Sams M. A. Sadat | Mehran Yarahmadi | Azita Haddadi

https://doi.org/10.1021/acs.molpharmaceut.8b00700 Actions

Raman Microscopy for Noninvasive Imaging of Pharmaceutical Nanocarriers: Intracellular Distribution of Cationic Liposomes of Different Composition

JOURNAL ARTICLE published 2 April 2012 in Molecular Pharmaceutics

Authors: T. Chernenko | R. R. Sawant | M. Miljkovic | L. Quintero | M. Diem | V. Torchilin

https://doi.org/10.1021/mp200519y Actions

Effect of Conformation on the Photodegradation of Trp- And Cystine-Containing Cyclic Peptides: Octreotide and Somatostatin

JOURNAL ARTICLE published 6 October 2014 in Molecular Pharmaceutics

Authors: Olivier Mozziconacci | Christian Schöneich

https://doi.org/10.1021/mp5003174 Actions

Integration of in Silico and in Vitro Tools for Scaffold Optimization during Drug Discovery: Predicting P-Glycoprotein Efflux

JOURNAL ARTICLE published 1 April 2013 in Molecular Pharmaceutics

Authors: Prashant V. Desai | Geri A. Sawada | Ian A. Watson | Thomas J. Raub

https://doi.org/10.1021/mp300555n Actions

Development of Nanodroplets for Histotripsy-Mediated Cell Ablation

JOURNAL ARTICLE published 6 October 2014 in Molecular Pharmaceutics

Research funded by Congressionally Directed Medical Research Programs (W81XWH-11-PCRP-ID)

Authors: Yasemin Yuksel Durmaz | Eli Vlaisavljevich | Zhen Xu | Mohamed ElSayed

https://doi.org/10.1021/mp500419w Actions

Solid-State Characterization and Relative Formation Enthalpies To Evaluate Stability of Cocrystals of an Antidiabetic Drug

JOURNAL ARTICLE published 7 May 2018 in Molecular Pharmaceutics

Authors: Naga Kiran Duggirala | Heather L. Frericks Schmidt | Zhaohui Lei | Michael J. Zaworotko | Joseph F. Krzyzaniak | Kapildev K. Arora

https://doi.org/10.1021/acs.molpharmaceut.8b00061 Actions
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