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Multifunctional Nanotheranostics for Dual-Modal Imaging-Guided Precision Therapy of Nasopharyngeal Carcinoma

JOURNAL ARTICLE published 4 September 2023 in Molecular Pharmaceutics

Research funded by National Natural Science Foundation of China (82260339,8226070069)

Authors: Qianyu Yang | Yingkun Guo | Yang Zhou | Jiali Song | Yujun Song | Hanmei Li | Huile Gao | Weiyuan Huang

Detecting Functional and Accessible Folate Receptor Expression in Cancer and Polycystic Kidneys

JOURNAL ARTICLE published 3 September 2019 in Molecular Pharmaceutics

Authors: Haiyan Chu | Jonathan M. Shillingford | Joseph A. Reddy | Elaine Westrick | Melissa Nelson | Emilia Z. Wang | Nikki Parker | Albert E. Felten | Jeremy F. Vaughn | Le-Cun Xu | Yingjuan J. Lu | Iontcho R. Vlahov | Christopher P. Leamon

Intracellular Delivery of Human Purine Nucleoside Phosphorylase by Engineered Diphtheria Toxin Rescues Function in Target Cells

JOURNAL ARTICLE published 5 November 2018 in Molecular Pharmaceutics

Authors: Minyoung Park | Xiaobai Xu | Weixian Min | Seiji N. Sugiman-Marangos | Greg L. Beilhartz | Jarret J. Adams | Sachdev S. Sidhu | Eyal Grunebaum | Roman A. Melnyk

Nanoparticle Size and Surface Charge Determine Effects of PAMAM Dendrimers on Human Platelets in Vitro

JOURNAL ARTICLE published 5 March 2012 in Molecular Pharmaceutics

Authors: Marina A. Dobrovolskaia | Anil K. Patri | Jan Simak | Jennifer B. Hall | Jana Semberova | Silvia H. De Paoli Lacerda | Scott E. McNeil

Bioengineered 3D Brain Tumor Model To Elucidate the Effects of Matrix Stiffness on Glioblastoma Cell Behavior Using PEG-Based Hydrogels

JOURNAL ARTICLE published 7 July 2014 in Molecular Pharmaceutics

Authors: Christine Wang | Xinming Tong | Fan Yang

Thermosensitive, Near-Infrared-Labeled Nanoparticles for Topotecan Delivery to Tumors

JOURNAL ARTICLE published 4 May 2015 in Molecular Pharmaceutics

Research funded by Engineering and Physical Sciences Research Council (EP/I001700/1)

Authors: Elena V. Rosca | Michael Wright | Roman Gonitel | Wladyslaw Gedroyc | Andrew D. Miller | Maya Thanou

Development of a Biomaterial Scaffold Integrated with Osteoinductive Oxysterol Liposomes to Enhance Hedgehog Signaling and Bone Repair

JOURNAL ARTICLE published 5 April 2021 in Molecular Pharmaceutics

Research funded by National Institute of Dental and Craniofacial Research (R01 DE027332,R21 DE027922) | U.S. Department of Defense (W81XWH-18-1-0121,W81XWH-18-1-0336,W81XWH-18-1-0337,W81XWH-18-1-0613) | American Cancer Society (RSG-18-027-01-CSM) | National Institute of Arthritis and Musculoskeletal and Skin Diseases (K08 AR068316,R01 AR070773)

Authors: Chung-Sung Lee | Ginny Ching-Yun Hsu | Takashi Sono | Min Lee | Aaron W. James

Therapeutic Potential of Quercetin-Loaded Nanoemulsion against Experimental Visceral Leishmaniasis: In Vitro/Ex Vivo Studies and Mechanistic Insights

JOURNAL ARTICLE published 5 September 2022 in Molecular Pharmaceutics

Authors: Sabya Sachi Das | Amit Kumar Dubey | Priya Ranjan Prasad Verma | Shubhankar Kumar Singh | Sandeep Kumar Singh

Preparation of a Self-Assembled Rhein–Doxorubicin Nanogel Targeting Mitochondria and Investigation on Its Antihepatoma Activity

JOURNAL ARTICLE published 3 January 2022 in Molecular Pharmaceutics

Research funded by National Natural Science Foundation of China (8187152059)

Authors: Li Wu | Yan Shi | Zihui Ni | Tao Yu | Zhipeng Chen

Studying the Crystallization of Various Polymorphic Forms of Nifedipine from Binary Mixtures with the Use of Different Experimental Techniques

JOURNAL ARTICLE published 5 June 2017 in Molecular Pharmaceutics

Research funded by Narodowe Centrum Nauki (DEC-2015/17/B/ST3/01195,DEC-2016/22/E/NZ7/00266)

Authors: O. Madejczyk | E. Kaminska | M. Tarnacka | M. Dulski | K. Jurkiewicz | K. Kaminski | M. Paluch

Enhanced Drug Loading in the Drug-in-Adhesive Transdermal Patch Utilizing a Drug–Ionic Liquid Strategy: Insight into the Role of Ionic Hydrogen Bonding

JOURNAL ARTICLE published 1 March 2021 in Molecular Pharmaceutics

Research funded by National Natural Science Foundation of China (81803468)

Authors: Degong Yang | Chao Liu | Huiqing Piao | Peng Quan | Liang Fang

Salt Disproportionation in the Solid State: Role of Solubility and Counterion Volatility

JOURNAL ARTICLE published 5 December 2016 in Molecular Pharmaceutics

Authors: Naveen K. Thakral | Robert J. Behme | Aktham Aburub | Jeffrey A. Peterson | Timothy A. Woods | Benjamin A. Diseroad | Raj Suryanarayanan | Gregory A. Stephenson

Biomimetic Nanovesicles for Enhanced Antitumor Activity of Combinational Photothermal and Chemotherapy

JOURNAL ARTICLE published 5 March 2018 in Molecular Pharmaceutics

Research funded by National Natural Science Foundation of China (81673374,81373360) | Wuhan Science and Technology Plan for Applied Fundamental Research (2017060201010146)

Authors: Tingting Wu | Dan Zhang | Qi Qiao | Xianya Qin | Conglian Yang | Miao Kong | Huan Deng | Zhiping Zhang

A Biopharmaceutical Perspective on Higher-Order Structure and Thermal Stability of mRNA Vaccines

JOURNAL ARTICLE published 4 July 2022 in Molecular Pharmaceutics

Authors: Marek Kloczewiak | Jessica M. Banks | Lin Jin | Mark L. Brader

Enhance Cancer Cell Recognition and Overcome Drug Resistance Using Hyaluronic Acid and α-Tocopheryl Succinate Based Multifunctional Nanoparticles

JOURNAL ARTICLE published 1 June 2015 in Molecular Pharmaceutics

Research funded by Ministry of Education of the People's Republic of China (20130001110055) | Ministry of Science and Technology of the People's Republic of China (2013CB932501) | Natural Science Foundation of Beijing Municipality (7132113) | National Natural Science Foundation of China (81273454,81473156)

Authors: Desheng Liang | Ai-ting Wang | Zhen-zhen Yang | Yu-jie Liu | Xian-rong Qi

Nuclear Localization of Cell-Penetrating Peptides Is Dependent on Endocytosis Rather Than Cytosolic Delivery in CHO Cells

JOURNAL ARTICLE published 6 April 2009 in Molecular Pharmaceutics

Authors: Jennica L. Zaro | Jacqueline E. Vekich | Thuy Tran | Wei-Chiang Shen

Lipid-Based Nanoparticles for Delivery of Vaccine Adjuvants and Antigens: Toward Multicomponent Vaccines

JOURNAL ARTICLE published 2 August 2021 in Molecular Pharmaceutics

Research funded by Horizon 2020 Framework Programme (H2020-MSCA-ITN-2015 Grant Agreement 675370)

Authors: Despo Chatzikleanthous | Derek T. O’Hagan | Roberto Adamo

Carboxymethyl Poly(l-histidine) as a New pH-Sensitive Polypeptide To Enhance Polyplex Gene Delivery

JOURNAL ARTICLE published 6 October 2008 in Molecular Pharmaceutics

Authors: Shoichiro Asayama | Miyuki Sudo | Shoji Nagaoka | Hiroyoshi Kawakami

Biodistribution Analysis of Peptide-Coated Magnetic Iron Nanoparticles: A Simple and Quantitative Method

JOURNAL ARTICLE published 5 February 2024 in Molecular Pharmaceutics

Research funded by Medical Research and Materiel Command (W81XWH-18-1-0716) | Agricultural Research Service (19-7483-1403-MT) | National Institute of General Medical Sciences (P20GM103418)

Authors: Pavithra Natarajan | Katherine Horak | Jennifer Rowe | Sungmin Yoon | Joshua Lingo | John M. Tomich | Sherry D. Fleming

Targeting Claudin 18.2 Using a Highly Specific Antibody Enables Cancer Diagnosis and Guided Surgery

JOURNAL ARTICLE published 3 October 2022 in Molecular Pharmaceutics

Research funded by Digestive Medical Coordinated Development Center of Beijing Hospitals Authority (XXT21) | National Natural Science Foundation of China (81671733,81871386) | Beijing Excellent Talents Funding (2017000021223ZK33) | Beijing Millions of Talent Projects A level funding (2019A38)

Authors: Chuanke Zhao | Zhuona Rong | Jin Ding | Lixin Wang | Bing Wang | Lei Ding | Lin Meng | Xiangxi Meng | Feng Wang | Zhi Yang | Chengchao Shou | Hua Zhu