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HDX and In Silico Docking Reveal that Excipients Stabilize G-CSF via a Combination of Preferential Exclusion and Specific Hotspot Interactions

JOURNAL ARTICLE published 7 December 2020 in Molecular Pharmaceutics

Research funded by Engineering and Physical Sciences Research Council (EP/I033270/1,EP/L015218/1,EP/P006485/1)

Authors: Victoria E. Wood | Kate Groves | Adam Cryar | Milena Quaglia | Paul Matejtschuk | Paul A. Dalby

https://doi.org/10.1021/acs.molpharmaceut.0c00877 Actions

Influence of Nucleation on Relaxation, Molecular Cooperativity, and Physical Stability of Celecoxib Glass

JOURNAL ARTICLE published 1 April 2024 in Molecular Pharmaceutics

Authors: Xue Han | Kexin Dai | Kohsaku Kawakami

https://doi.org/10.1021/acs.molpharmaceut.3c01116 Actions

Nebulization and In Vitro Upper Airway Deposition of Liposomal Carrier Systems

JOURNAL ARTICLE published 1 April 2024 in Molecular Pharmaceutics

Research funded by Grantov? Agentura Cesk? Republiky (GA22-20357S) | Vysok? Ucen? Technick? v Brne (FSI-S-23-8192)

Authors: Ondrej Mišík | Jana Kejíková | Ondřej Cejpek | Milan Malý | Adam Jugl | Miloslav Bělka | Filip Mravec | František Lízal

https://doi.org/10.1021/acs.molpharmaceut.3c01146 Actions

Photodynamic Therapy Induced Mitochondrial Targeting Strategies for Cancer Treatment: Emerging Trends and Insights

JOURNAL ARTICLE published 1 April 2024 in Molecular Pharmaceutics

Authors: Vaibhavi Meghraj Desai | Mahima Choudhary | Rajdeep Chowdhury | Gautam Singhvi

https://doi.org/10.1021/acs.molpharmaceut.3c01185 Actions

Dissolution Mechanisms of Amorphous Solid Dispersions: Application of Ternary Phase Diagrams To Explain Release Behavior

JOURNAL ARTICLE published 1 April 2024 in Molecular Pharmaceutics

Authors: Alexandru Deac | Christian Luebbert | Qingqing Qi | Reagan M. Courtney | Anura S. Indulkar | Yi Gao | Geoff G. Z. Zhang | Gabriele Sadowski | Lynne S. Taylor

https://doi.org/10.1021/acs.molpharmaceut.3c01179 Actions

Interactive Associations of Drug–Drug and Drug–Drug–Drug with IIA Subdomain of Human Serum Albumin

JOURNAL ARTICLE published 5 November 2012 in Molecular Pharmaceutics

Authors: Feng Yang | Jiping Yue | Li Ma | Zhiyuan Ma | Mei Li | Xiaoyang Wu | Hong Liang

https://doi.org/10.1021/mp300322y Actions

Poloxamer 188-Coated Ammonium Methacrylate Copolymer Nanocarriers Enhance Loperamide Permeability across Pgp-Expressing Epithelia

JOURNAL ARTICLE published 1 February 2021 in Molecular Pharmaceutics

Research funded by Comisi?n Nacional de Investigaci?n Cient?fica y Tecnol?gica (15130011,21120192,ACT192144) | Fondo Nacional de Desarrollo Cient?fico y Tecnol?gico (1181689)

Authors: Johanna Catalan-Figueroa | Mauricio A. García | Pilar Contreras | Constanza B. Boisset | Pablo M. Gonzalez | Jenny L. Fiedler | Mariela F. Pérez | Javier O. Morales

https://doi.org/10.1021/acs.molpharmaceut.0c00623 Actions

Highly Selective Protein Tyrosine Phosphatase Inhibitor, 2,2′,3,3′-Tetrabromo-4,4′,5,5′-tetrahydroxydiphenylmethane, Ameliorates Type 2 Diabetes Mellitus in BKS db Mice

JOURNAL ARTICLE published 6 May 2019 in Molecular Pharmaceutics

Research funded by National Natural Science Foundation of China (81703354,81773586) | Chinese Academy of Sciences (QYZDB-SSW-DQC014) | Shandong Provincial Natural Science Foundation for Distinguished Young Scholars (JQ201722) | Qingdao Marine Biomedical Science and Technology Innovation Center (2017-CXZX01-1-1,2017-CXZX01-3-9)

Authors: Chao Li | Jiao Luo | Shuju Guo | Xiaoling Jia | Chuanlong Guo | Xiangqian Li | Qi Xu | Dayong Shi

https://doi.org/10.1021/acs.molpharmaceut.8b01106 Actions

Induced Disorder in Protein−Ligand Complexes as a Drug-Design Strategy

JOURNAL ARTICLE published 4 October 2010 in Molecular Pharmaceutics

Authors: Alejandro Crespo | Ariel Fernández

https://doi.org/10.1021/mp100057w Actions

Correction to July/August 2010 Cover Caption

JOURNAL ARTICLE published 4 October 2010 in Molecular Pharmaceutics

https://doi.org/10.1021/mp1002784 Actions

Selection of Bioavailability Markers for Herbal Extracts Based on In Silico Descriptors and Their Correlation to In Vitro Permeability

JOURNAL ARTICLE published 1 August 2008 in Molecular Pharmaceutics

Authors: Devendra Pade | Salomon Stavchansky

https://doi.org/10.1021/mp700153h Actions

Issue Editorial Masthead

JOURNAL ARTICLE published 7 May 2018 in Molecular Pharmaceutics

https://doi.org/10.1021/mpv015i005_1187457 Actions

Issue Editorial Masthead

JOURNAL ARTICLE published 2 January 2018 in Molecular Pharmaceutics

https://doi.org/10.1021/mpv015i001_1158045 Actions

Conjugation of β-Glucan with the Hydrazone and Disulfide Linkers Markedly Improves the Immunogenicity of Zika Virus E Protein

JOURNAL ARTICLE published 1 June 2020 in Molecular Pharmaceutics

Research funded by Ministry of Science and Technology of the People's Republic of China (2018YFA0900804) | National Natural Science Foundation of China (31970875,81700181,81703445)

Authors: Jinming Qi | Ying Yin | Weili Yu | Lijuan Shen | Junjie Xu | Tao Hu

https://doi.org/10.1021/acs.molpharmaceut.0c00010 Actions

Pharmacokinetic Characterization of [18F]UCB-H PET Radiopharmaceutical in the Rat Brain

JOURNAL ARTICLE published 7 August 2017 in Molecular Pharmaceutics

Research funded by Universit? de Li?ge (13/17-07)

Authors: Guillaume Becker | Corentin Warnier | Maria Elisa Serrano | Mohamed Ali Bahri | Joël Mercier | Christian Lemaire | Eric Salmon | André Luxen | Alain Plenevaux

https://doi.org/10.1021/acs.molpharmaceut.7b00235 Actions

Design of PLGA Based Nanoparticles for Imaging Guided Applications

JOURNAL ARTICLE published 3 November 2014 in Molecular Pharmaceutics

Authors: Rodolfo Nicolás Mariano | Diego Alberti | Juan Carlos Cutrin | Simonetta Geninatti Crich | Silvio Aime

https://doi.org/10.1021/mp5002747 Actions

Mechanistic Investigation of Drug Supersaturation in the Presence of Polysorbates as Solubilizing Additives by Solution Nuclear Magnetic Resonance Spectroscopy

JOURNAL ARTICLE published 6 December 2021 in Molecular Pharmaceutics

Research funded by Division of Industrial Innovation and Partnerships (IIP-1540011)

Authors: Xingyu Lu | Mingyue Li | Freddy A. Arce | Jing Ling | Nico Setiawan | Yaqiang Wang | Xiaohuo Shi | Heather R. Campbell | Matthew J. Nethercott | Wei Xu | Eric J. Munson | Patrick J. Marsac | Yongchao Su

https://doi.org/10.1021/acs.molpharmaceut.1c00477 Actions

Viruses in Pharmaceutical Research: Swiss Army Knives for the Prevention and Treatment of Disease

JOURNAL ARTICLE published 7 February 2011 in Molecular Pharmaceutics

Authors: Maaike Everts

https://doi.org/10.1021/mp100428c Actions

Positron-Emission Tomography of HER2-Positive Breast Cancer Xenografts in Mice with 89Zr-Labeled Trastuzumab-DM1: A Comparison with 89Zr-Labeled Trastuzumab

JOURNAL ARTICLE published 6 August 2018 in Molecular Pharmaceutics

Authors: Noor Al-saden | Karen Lam | Conrad Chan | Raymond M. Reilly

https://doi.org/10.1021/acs.molpharmaceut.8b00392 Actions

Mitigation of Adverse Clinical Events of a Narrow Target Therapeutic Index Compound through Modified Release Formulation Design: An in Vitro, in Vivo, in Silico, and Clinical Pharmacokinetic Analysis

JOURNAL ARTICLE published 7 December 2015 in Molecular Pharmaceutics

Authors: David J. Good | Ruiling Hartley | Neil Mathias | John Crison | Giridhar Tirucherai | Peter Timmins | Munir Hussain | Raja Haddadin | Otilia Koo | Faranak Nikfar | Nga Kit Eliza Fung

https://doi.org/10.1021/acs.molpharmaceut.5b00624 Actions
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