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Leveraging BCS in Development: A Case Study

JOURNAL ARTICLE published 5 October 2015 in Molecular Pharmaceutics

Authors: Cherokee Sue Hoaglund Hyzer | Hala M. Fadda | Jole O. Rodriguez | Aktham Aburub

Investigation of Receptor-Mediated Cyanocobalamin (Vitamin B12) Transport across the Inner Blood–Retinal Barrier Using Fluorescence-Labeled Cyanocobalamin

JOURNAL ARTICLE published 6 August 2018 in Molecular Pharmaceutics

Research funded by Japan Society for the Promotion of Science (Core-to-Core Program (B. Asia-Africa Science Platf,JP16H05110,JP17K08409) | The Takeda Science Foundation (N/A)

Authors: Yuri Kinoshita | Kagayaki Nogami | Ryuta Jomura | Shin-ichi Akanuma | Hajime Abe | Masahiko Inouye | Yoshiyuki Kubo | Ken-ichi Hosoya

Correction to “Assessing the Dual Activity of a Chalcone–Phthalocyanine Conjugate: Design, Synthesis, and Antivascular and Photodynamic Properties”

JOURNAL ARTICLE published 2 February 2015 in Molecular Pharmaceutics

Authors: Sinem Tuncel | Aurélien Trivella | Devrim Atilla | Khalil Bennis | Huguette Savoie | Florian Albrieux | Laetitia Delort | Hermine Billard | Virginie Dubois | Vefa Ahsen | Florence Caldefie-Chézet | Claire Richard | Ross W. Boyle | Sylvie Ducki | Fabienne Dumoulin

Expression of Concentrative Nucleoside Transporters (SLC28A) in the Human Placenta: Effects of Gestation Age and Prototype Differentiation-Affecting Agents

JOURNAL ARTICLE published 2 July 2018 in Molecular Pharmaceutics

Research funded by Grantov?? Agentura ?esk?? Republiky (17-16169S) | SVV (2017/260-414) | Grantova Agentura, Univerzita Karlova (GAUK 324215/C/2015,GAUK 812216/C/2016)

Authors: Lucie Jiraskova | Lukas Cerveny | Sara Karbanova | Zuzana Ptackova | Frantisek Staud

Crown Ethers: Novel Permeability Enhancers for Ocular Drug Delivery?

JOURNAL ARTICLE published 2 October 2017 in Molecular Pharmaceutics

Research funded by Biotechnology and Biological Sciences Research Council (BB/F017189/1)

Authors: Peter W. J. Morrison | Natalia N. Porfiryeva | Sukhmanpreet Chahal | Ilgiz A. Salakhov | Charlène Lacourt | Irina I. Semina | Rouslan I. Moustafine | Vitaliy V. Khutoryanskiy

Molecular Dynamics Studies on the Water Mixtures of Pharmaceutically Important Ionic Liquid Lidocaine HCl

JOURNAL ARTICLE published 7 May 2012 in Molecular Pharmaceutics

Authors: Z. Wojnarowska | K. Grzybowska | L. Hawelek | A. Swiety-Pospiech | E. Masiewicz | M. Paluch | W. Sawicki | A. Chmielewska | P. Bujak | J. Markowski

Brain Delivery of Drug and MRI Contrast Agent: Detection and Quantitative Determination of Brain Deposition of CPT-Glu Using LC–MS/MS and Gd-DTPA Using Magnetic Resonance Imaging

JOURNAL ARTICLE published 1 February 2016 in Molecular Pharmaceutics

Research funded by National Institute of Neurological Disorders and Stroke (R01-NS075374) | National Center for Research Resources (S10-RR29577,UL1-RR033179) | National Institute of Child Health and Human Development (P30-HD002528) | National Institute on Aging (P30-AG035982) | National Institute of General Medical Sciences (R25-GM062881)

Authors: Kayann Tabanor | Phil Lee | Paul Kiptoo | In-Young Choi | Erica B. Sherry | Cheyenne Sun Eagle | Todd D. Williams | Teruna J. Siahaan

HDX and In Silico Docking Reveal that Excipients Stabilize G-CSF via a Combination of Preferential Exclusion and Specific Hotspot Interactions

JOURNAL ARTICLE published 7 December 2020 in Molecular Pharmaceutics

Research funded by Engineering and Physical Sciences Research Council (EP/I033270/1,EP/L015218/1,EP/P006485/1)

Authors: Victoria E. Wood | Kate Groves | Adam Cryar | Milena Quaglia | Paul Matejtschuk | Paul A. Dalby

Photodynamic Therapy Induced Mitochondrial Targeting Strategies for Cancer Treatment: Emerging Trends and Insights

JOURNAL ARTICLE published 1 April 2024 in Molecular Pharmaceutics

Authors: Vaibhavi Meghraj Desai | Mahima Choudhary | Rajdeep Chowdhury | Gautam Singhvi

Dissolution Mechanisms of Amorphous Solid Dispersions: Application of Ternary Phase Diagrams To Explain Release Behavior

JOURNAL ARTICLE published 1 April 2024 in Molecular Pharmaceutics

Authors: Alexandru Deac | Christian Luebbert | Qingqing Qi | Reagan M. Courtney | Anura S. Indulkar | Yi Gao | Geoff G. Z. Zhang | Gabriele Sadowski | Lynne S. Taylor

Nebulization and In Vitro Upper Airway Deposition of Liposomal Carrier Systems

JOURNAL ARTICLE published 1 April 2024 in Molecular Pharmaceutics

Research funded by Grantov? Agentura Cesk? Republiky (GA22-20357S) | Vysok? Ucen? Technick? v Brne (FSI-S-23-8192)

Authors: Ondrej Mišík | Jana Kejíková | Ondřej Cejpek | Milan Malý | Adam Jugl | Miloslav Bělka | Filip Mravec | František Lízal

A Pseudopolyrotaxane for Glucose-Responsive Insulin Release: The Effect of Binding Ability and Spatial Arrangement of Phenylboronic Acid Group

JOURNAL ARTICLE published 7 November 2016 in Molecular Pharmaceutics

Research funded by Japan Society for the Promotion of Science (25860027)

Authors: Tomohiro Seki | Keigo Abe | Yuya Egawa | Ryotaro Miki | Kazuhiko Juni | Toshinobu Seki

Immuno-PET Imaging of TNF-α in Colitis Using 89Zr-DFO-infliximab

JOURNAL ARTICLE published 3 October 2022 in Molecular Pharmaceutics

Research funded by Government of Jiangsu Province (BK20192005) | National Natural Science Foundation of China (22075114,31971316,51803082) | Jiangsu Association of Science and Technology (2021011)

Authors: Ge Yan | Xinyu Wang | Yeli Fan | Jianhan Lin | Junjie Yan | Lizhen Wang | Donghui Pan | Yuping Xu | Min Yang

Conjugation of β-Glucan with the Hydrazone and Disulfide Linkers Markedly Improves the Immunogenicity of Zika Virus E Protein

JOURNAL ARTICLE published 1 June 2020 in Molecular Pharmaceutics

Research funded by Ministry of Science and Technology of the People's Republic of China (2018YFA0900804) | National Natural Science Foundation of China (31970875,81700181,81703445)

Authors: Jinming Qi | Ying Yin | Weili Yu | Lijuan Shen | Junjie Xu | Tao Hu

Endocytic Pathway and Resistance to Cholesterol Depletion of Cholesterol Derived Cationic Lipids for Gene Delivery

JOURNAL ARTICLE published 3 December 2012 in Molecular Pharmaceutics

Authors: Yun-Ui Bae | Bieong-Kil Kim | Jong-Won Park | Young-Bae Seu | Kyung-Oh Doh

miR-194-Loaded Gelatin Nanospheres Target MEF2C to Suppress Muscle Atrophy in a Mechanical Unloading Model

JOURNAL ARTICLE published 2 August 2021 in Molecular Pharmaceutics

Research funded by China Postdoctoral Science Foundation (2019T120948) | National Natural Science Foundation of China (11202167,31800802) | Northwestern Polytechnical University (CX2021096) | Shaanxi Province Postdoctoral Science Foundation (2018BSHEDZZ02) | Undergraduate Training Programs for Innovation and Entrepreneurship (S201910699106,S202010699078,S202010699218) | Shaanxi Provincial Key R&D Program (2018KW-031,2021KW-62) | Innovation Capability Support Program of Shaanxi (2020TD-042)

Authors: Chen-Yan Zhang | Chang-Qing Yang | Qiang Chen | Jie Liu | Ge Zhang | Chen Dong | Xin-Li Liu | Hafiz Muhammad Umer Farooq | Shi-Qi Zhao | Li-Heng Luo | Shan-Feng Jiang | Yin-Bo Niu | Da-Chuan Yin

Probing Hydrogen Bonding in Cocrystals and Amorphous Dispersions Using 14N–1H HMQC Solid-State NMR

JOURNAL ARTICLE published 4 March 2013 in Molecular Pharmaceutics

Authors: Andrew S. Tatton | Tran N. Pham | Frederick G. Vogt | Dinu Iuga | Andrew J. Edwards | Steven P. Brown

Synthesis and Preclinical Evaluation of 18F-PEG3-FPN for the Detection of Metastatic Pigmented Melanoma

JOURNAL ARTICLE published 6 November 2017 in Molecular Pharmaceutics

Research funded by National Natural Science Foundation of China (81371626)

Authors: Xiaodong Xu | Lujie Yuan | Lianglan Yin | Yaqun Jiang | Yongkang Gai | Qingyao Liu | Yichun Wang | Yongxue Zhang | Xiaoli Lan

Relative Humidity Cycling: Implications on the Stability of Moisture-Sensitive Drugs in Solid Pharmaceutical Products

JOURNAL ARTICLE published 6 February 2023 in Molecular Pharmaceutics

Research funded by GEA-NUS PPRL fund (N-148-000-008-001)

Authors: Natalia Veronica | Paul Wan Sia Heng | Celine Valeria Liew

Highly Viscous Antibody Solutions Are a Consequence of Network Formation Caused by Domain–Domain Electrostatic Complementarities: Insights from Coarse-Grained Simulations

JOURNAL ARTICLE published 5 January 2015 in Molecular Pharmaceutics

Authors: Patrick M. Buck | Anuj Chaudhri | Sandeep Kumar | Satish K. Singh