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Detecting Functional and Accessible Folate Receptor Expression in Cancer and Polycystic Kidneys

JOURNAL ARTICLE published 3 September 2019 in Molecular Pharmaceutics

Authors: Haiyan Chu | Jonathan M. Shillingford | Joseph A. Reddy | Elaine Westrick | Melissa Nelson | Emilia Z. Wang | Nikki Parker | Albert E. Felten | Jeremy F. Vaughn | Le-Cun Xu | Yingjuan J. Lu | Iontcho R. Vlahov | Christopher P. Leamon

Intracellular Delivery of Human Purine Nucleoside Phosphorylase by Engineered Diphtheria Toxin Rescues Function in Target Cells

JOURNAL ARTICLE published 5 November 2018 in Molecular Pharmaceutics

Authors: Minyoung Park | Xiaobai Xu | Weixian Min | Seiji N. Sugiman-Marangos | Greg L. Beilhartz | Jarret J. Adams | Sachdev S. Sidhu | Eyal Grunebaum | Roman A. Melnyk

Mathematical Modeling and Experimental Validation of Extracellular Vesicle-Mediated Tumor Suppressor MicroRNA Delivery and Propagation in Ovarian Cancer Cells

JOURNAL ARTICLE published 7 November 2022 in Molecular Pharmaceutics

Research funded by National Cancer Institute (R21-CA179652,R56-CA198492)

Authors: Srujan K. Gandham | Husain Z. Attarwala | Mansoor M. Amiji

pH/Hyal-Responsive Surface-Charge Switchable Electrostatic Complexation for Efficient Elimination of MRSA Infection

JOURNAL ARTICLE published 3 July 2023 in Molecular Pharmaceutics

Research funded by Taishan Scholar Project of Shandong Province (tsqn201909143) | Natural Science Foundation of Shandong Province (ZR2020KE015) | ShanDong College Students? Innovation and Entrepreneurship Training Program (S202110440054)

Authors: Wenting Li | Qing Fan | Wei Cong | Longle Wang | Xueling Li | Weiwei Li | Senhao Hu | Xiangjun Chen | Wei Hong

Exploring the Potent Combination of Quercetin–Boronic Acid, Epalrestat, and Urea Containing Nanoethosomal Keratolytic Gel for the Treatment of Diabetic Neuropathic Pain: In Vitro and In Vivo Studies

JOURNAL ARTICLE published 3 July 2023 in Molecular Pharmaceutics

Authors: Hafiz Muhammad Usman Abid | Muhammad Hanif | Khalid Mahmood | Sobia Abid | Mehran Khan | Umair Khurshid | Muhammad Azeem | Nabeela Ameer | Fazal Rahman Sajid Chughtai | Kapil Pandey | Muhammad Qaiser | Zeeshan Danish | Ghulam Razaque

Enhanced Opsonization-Independent Phagocytosis and High Response Ability to Opsonized Antigen–Antibody Complexes: A New Role of Kupffer Cells in the Accelerated Blood Clearance Phenomenon upon Repeated Injection of PEGylated Emulsions

JOURNAL ARTICLE published 4 September 2018 in Molecular Pharmaceutics

Research funded by National Natural Science Foundation of China (81573375)

Authors: Xiaobo Cheng | Chunling Wang | Yuqing Su | Xiang Luo | Xinrong Liu | Yanzhi Song | Yihui Deng

Cationic Lipophosphoramidates Containing a Hydroxylated Polar Headgroup for Improving Gene Delivery

JOURNAL ARTICLE published 1 June 2015 in Molecular Pharmaceutics

Authors: Mathieu Berchel | Tony Le Gall | Jean-Pierre Haelters | Pierre Lehn | Tristan Montier | Paul-Alain Jaffrès

Anionic Amino Acid Dendrimer−Trastuzumab Conjugates for Specific Internalization in HER2-Positive Cancer Cells

JOURNAL ARTICLE published 2 August 2010 in Molecular Pharmaceutics

Authors: Takuya Miyano | Wassana Wijagkanalan | Shigeru Kawakami | Fumiyoshi Yamashita | Mitsuru Hashida

Development of a Biomaterial Scaffold Integrated with Osteoinductive Oxysterol Liposomes to Enhance Hedgehog Signaling and Bone Repair

JOURNAL ARTICLE published 5 April 2021 in Molecular Pharmaceutics

Research funded by National Institute of Dental and Craniofacial Research (R01 DE027332,R21 DE027922) | U.S. Department of Defense (W81XWH-18-1-0121,W81XWH-18-1-0336,W81XWH-18-1-0337,W81XWH-18-1-0613) | American Cancer Society (RSG-18-027-01-CSM) | National Institute of Arthritis and Musculoskeletal and Skin Diseases (K08 AR068316,R01 AR070773)

Authors: Chung-Sung Lee | Ginny Ching-Yun Hsu | Takashi Sono | Min Lee | Aaron W. James

Enhance Cancer Cell Recognition and Overcome Drug Resistance Using Hyaluronic Acid and α-Tocopheryl Succinate Based Multifunctional Nanoparticles

JOURNAL ARTICLE published 1 June 2015 in Molecular Pharmaceutics

Research funded by Ministry of Education of the People's Republic of China (20130001110055) | Ministry of Science and Technology of the People's Republic of China (2013CB932501) | Natural Science Foundation of Beijing Municipality (7132113) | National Natural Science Foundation of China (81273454,81473156)

Authors: Desheng Liang | Ai-ting Wang | Zhen-zhen Yang | Yu-jie Liu | Xian-rong Qi

Carboxymethyl Poly(l-histidine) as a New pH-Sensitive Polypeptide To Enhance Polyplex Gene Delivery

JOURNAL ARTICLE published 6 October 2008 in Molecular Pharmaceutics

Authors: Shoichiro Asayama | Miyuki Sudo | Shoji Nagaoka | Hiroyoshi Kawakami

Biodistribution Analysis of Peptide-Coated Magnetic Iron Nanoparticles: A Simple and Quantitative Method

JOURNAL ARTICLE published 5 February 2024 in Molecular Pharmaceutics

Research funded by Medical Research and Materiel Command (W81XWH-18-1-0716) | Agricultural Research Service (19-7483-1403-MT) | National Institute of General Medical Sciences (P20GM103418)

Authors: Pavithra Natarajan | Katherine Horak | Jennifer Rowe | Sungmin Yoon | Joshua Lingo | John M. Tomich | Sherry D. Fleming

Nanoformulation of EPZ011989 Attenuates EZH2–c-Myb Epigenetic Interaction by Proteasomal Degradation in Acute Myeloid Leukemia

JOURNAL ARTICLE published 6 January 2020 in Molecular Pharmaceutics

Research funded by Department of Science and Technology, Ministry of Science and Technology (YSS/2015/001706)

Authors: Babita Kaundal | Anup K. Srivastava | Atul Dev | Soni Jignesh Mohanbhai | Surajit Karmakar | Subhasree Roy Choudhury

Dynamic Analysis of Fluid Distribution in the Gastrointestinal Tract in Rats: Positron Emission Tomography Imaging after Oral Administration of Nonabsorbable Marker, [18F]Deoxyfluoropoly(ethylene glycol)

JOURNAL ARTICLE published 3 June 2013 in Molecular Pharmaceutics

Authors: Tadayuki Takashima | Tomotaka Shingaki | Yumiko Katayama | Emi Hayashinaka | Yasuhiro Wada | Makoto Kataoka | Daiki Ozaki | Hisashi Doi | Masaaki Suzuki | Sho Ishida | Kentaro Hatanaka | Yuichi Sugiyama | Shuji Akai | Naoto Oku | Shinji Yamashita | Yasuyoshi Watanabe

Mouse Bone Marrow Mesenchymal Stem Cells Inhibit Sepsis-Induced Lung Injury in Mice via Exosomal SAA1

JOURNAL ARTICLE published 7 November 2022 in Molecular Pharmaceutics

Research funded by Science and Technology Commission of Shanghai Municipality (19YF1432600) | National Natural Science Foundation of China (81901990,81901991)

Authors: Zhou Lv | Shuxian Duan | Miao Zhou | Minglu Gu | Siyuan Li | Yan Wang | Qin Xia | Dunfeng Xu | Yanfei Mao | Wenwen Dong | Lai Jiang

Improved Efficiency of Ibuprofen by Cationic Carbosilane Dendritic Conjugates

JOURNAL ARTICLE published 3 October 2016 in Molecular Pharmaceutics

Research funded by Ministerstwo Nauki i Szkolnictwa Wyzszego (W21/7PR/ 2013) | Ministerio de Economía y Competitividad (CTQ-2014-54004-P,CYTED 214RT0482) | Directorate-General for Research and Innovation (316730) | Instituto de Salud Carlos III (PI12/0014,PI13/02016,RD12/0017/0037,RETIC-PT13/0010/0028) | Comunidad de Madrid (S-2010/BMD-2332,S2011/BMD-2351)

Authors: Ana Judith Perisé-Barrios | Elena Fuentes-Paniagua | Javier Sánchez-Nieves | M. Jesús Serramía | Esther Alonso | Rosa M. Reguera | Rafael Gómez | F. Javier de la Mata | M. Ángeles Muñoz-Fernández

Hinge-Deficient IgG1 Fc Fusion: Application to Human Lactoferrin

JOURNAL ARTICLE published 5 September 2017 in Molecular Pharmaceutics

Authors: Yuki Shiga | Daisuke Murata | Akinori Sugimoto | Yuta Oshima | Minoru Tada | Akiko Ishii-Watabe | Kenichiro Imai | Kentaro Tomii | Takashi Takeuchi | Shinji Kagaya | Atsushi Sato

Modified Release and Improved Stability of Unstable BCS II Drug by Using Cyclodextrin Complex as Carrier To Remotely Load Drug into Niosomes

JOURNAL ARTICLE published 4 January 2016 in Molecular Pharmaceutics

Research funded by National Natural Science Foundation of China (81373358,81430087)

Authors: Liandi Chi | Delin Wu | Zhuo Li | Minmin Zhang | Hongchun Liu | Caifen Wang | Shuangying Gui | Meiyu Geng | Haiyan Li | Jiwen Zhang

Controlled Release of Salicylic Acid from Biodegradable Cross-Linked Polyesters

JOURNAL ARTICLE published 8 September 2015 in Molecular Pharmaceutics

Research funded by Department of Biotechnology , Ministry of Science and Technology (BT/PR5977/MED/32/242/2012)

Authors: Queeny Dasgupta | Kaushik Chatterjee | Giridhar Madras

In Vitro Release from Polymeric Core/Shell Nanoparticles through the Lens of Multiscale Modeling

JOURNAL ARTICLE published 30 April 2024 in Molecular Pharmaceutics

Authors: Tommaso Casalini | Kevin Treacher | Iain Grant | Mariagrazia Marucci