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Intermittent hypoxia treatment alleviates memory impairment in the 6-month-old APPswe/PS1dE9 mice and reduces amyloid beta accumulation and inflammation in the brain

JOURNAL ARTICLE published 29 November 2021 in Alzheimer's Research & Therapy

Research funded by beijing science and technology planning project (Z161100000216134) | national natural science foundation of china (81430044)

Authors: Xiangpei Yue | Yanzhao Zhou | Meng Qiao | Xingnan Zhao | Xin Huang | Tong Zhao | Xiang Cheng | Ming Fan | Yongqi Zhao | Ruoli Chen | Lingling Zhu

A nonhuman primate model with Alzheimer’s disease-like pathology induced by hippocampal overexpression of human tau

JOURNAL ARTICLE published 27 January 2024 in Alzheimer's Research & Therapy

Research funded by Guangdong Provincial Department of Science and Technology (2018B030332001) | Guangzhou Municipal Science and Technology Bureau (202206060002,202206060002) | National Natural Science Foundation of China (31970906) | Natural Science Foundation of Guangdong Province (2020A1515010083)

Authors: Zhouquan Jiang | Jing Wang | Yongpeng Qin | Shanggong Liu | Bin Luo | Fan Bai | Huiyi Wei | Shaojuan Zhang | Junjie Wei | Guoyu Ding | Long Ma | Shu He | Rongjie Chen | Ying Sun | Yi Chen | Lu Wang | Hao Xu | Xiangyu Wang | Gong Chen | Wenliang Lei

The course of primary progressive aphasia diagnosis: a cross-sectional study

JOURNAL ARTICLE published December 2022 in Alzheimer's Research & Therapy

Authors: A. Mouton | A. Plonka | R. Fabre | T. M. Tran | P. Robert | J. Macoir | V. Manera | A. Gros

Prevalence of mixed pathologies in the aging brain

JOURNAL ARTICLE published December 2014 in Alzheimer's Research & Therapy

Authors: Jasmin Rahimi | Gabor G Kovacs

Serum and cerebrospinal fluid neurofilament light chain and glial fibrillary acid protein levels in early and advanced stages of cerebral amyloid Angiopathy

JOURNAL ARTICLE published 23 April 2024 in Alzheimer's Research & Therapy

Research funded by Dutch Heart Foundation (2012 T077,2019 T060,2016 T086) | the Netherlands Organisation for Health Research and Development (ZonMw; 015008048,ZonMW, nr. 733050822) | National Institutes of Health, USA (5R01NS104147-02) | The Galen and Hilary Weston Foundation (NR170024) | The Netherlands Organization for Health Research and Development (DR-2019-00299) | Alzheimer’s Disease Research program of the BrightFocus Foundation (A2021007F) | from the Netherlands Organisation for Health Research and Development (91717337)

Authors: Ingeborg Rasing | Sabine Voigt | Emma A. Koemans | Anna M. de Kort | Thijs W. van Harten | Ellis S. van Etten | Erik W. van Zwet | Erik Stoops | Cindy Francois | Bea H. Kuiperij | Catharina J.M. Klijn | Floris H.B.M. Schreuder | Louise van der Weerd | Matthias J.P. van Osch | Marianne A.A. van Walderveen | Marcel M. Verbeek | Gisela M. Terwindt | Marieke J.H. Wermer

Simulations of symptomatic treatments for Alzheimer's disease: computational analysis of pathology and mechanisms of drug action

JOURNAL ARTICLE published 2012 in Alzheimer's Research & Therapy

Authors: Patrick D Roberts | Athan Spiros | Hugo Geerts

Granulovacuolar degeneration bodies are independently induced by tau and α-synuclein pathology

JOURNAL ARTICLE published 14 December 2022 in Alzheimer's Research & Therapy

Research funded by Alzheimer Nederland (#WE.03-2017-10) | Coby van Nieuwkerk fonds (Hersenstichting Nederland #DR-2019-00278)

Authors: Marta Jorge-Oliva | Jasper F. M. Smits | Vera I. Wiersma | Jeroen J. M. Hoozemans | Wiep Scheper

The need for thorough phase II studies in medicines development for Alzheimer’s disease

JOURNAL ARTICLE published December 2015 in Alzheimer's Research & Therapy

Authors: Julian A. Gray | David Fleet | Bengt Winblad

Cognitive impact after short-term exposure to different proton pump inhibitors: assessment using CANTAB software

JOURNAL ARTICLE published December 2015 in Alzheimer's Research & Therapy

Authors: Sanjida Akter | Md. Rajib Hassan | Mohammad Shahriar | Nahia Akter | Md. Golam Abbas | Mohiuddin Ahmed Bhuiyan

Phenotypic differences between apolipoprotein E genetic subgroups: research and clinical implications

JOURNAL ARTICLE published 2012 in Alzheimer's Research & Therapy

Authors: Richard J Caselli

ABT-126 monotherapy in mild-to-moderate Alzheimer’s dementia: randomized double-blind, placebo and active controlled adaptive trial and open-label extension

JOURNAL ARTICLE published December 2016 in Alzheimer's Research & Therapy

Authors: Laura M. Gault | Robert A. Lenz | Craig W. Ritchie | Andreas Meier | Ahmed A. Othman | Qi Tang | Scott Berry | Yili Pritchett | Weining Z. Robieson

Leading mediators of sex differences in the incidence of dementia in community-dwelling adults in the UK Biobank: a retrospective cohort study

JOURNAL ARTICLE published 9 January 2023 in Alzheimer's Research & Therapy

Research funded by Postdoctoral Research Funds of Guangdong Provincial People’s Hospital (BY012021047) | High-level Talent Flexible Introduction Fund of Guangdong Provincial People’s Hospital (KJ012019530)

Authors: Xianwen Shang | Eddy Roccati | Zhuoting Zhu | Katerina Kiburg | Wei Wang | Yu Huang | Xueli Zhang | Xiayin Zhang | Jiahao Liu | Shulin Tang | Yijun Hu | Zongyuan Ge | Honghua Yu | Mingguang He

Olfactory function is associated with cognitive performance: results from the population-based LIFE-Adult-Study

JOURNAL ARTICLE published December 2019 in Alzheimer's Research & Therapy

Authors: Maryam Yahiaoui-Doktor | Tobias Luck | Steffi G. Riedel-Heller | Markus Loeffler | Kerstin Wirkner | Christoph Engel

Heterogeneity of Alzheimer’s disease: consequence for drug trials?

JOURNAL ARTICLE published December 2018 in Alzheimer's Research & Therapy

Authors: Gayatri Devi | Philip Scheltens

Correction to: Neurexin 3 transmembrane and soluble isoform expression and splicing haplotype are associated with neuron inflammasome and Alzheimer’s disease

JOURNAL ARTICLE published December 2019 in Alzheimer's Research & Therapy

Authors: Akitoyo Hishimoto | Olga Pletnikova | Doyle Lu Lang | Juan C. Troncoso | Josephine M. Egan | Qing-Rong Liu

Correction to: Amyloid-β misfolding as a plasma biomarker indicates risk for future clinical Alzheimer’s disease in individuals with subjective cognitive decline

JOURNAL ARTICLE published December 2021 in Alzheimer's Research & Therapy

Authors: Julia Stockmann | Inge M. W. Verberk | Nina Timmesfeld | Robin Denz | Brian Budde | Julia Lange-Leifhelm | Philip Scheltens | Wiesje M. van der Flier | Andreas Nabers | Charlotte E. Teunissen | Klaus Gerwert

Transcranial magnetic stimulation and amyloid markers in mild cognitive impairment: impact on diagnostic confidence and diagnostic accuracy

JOURNAL ARTICLE published December 2019 in Alzheimer's Research & Therapy

Authors: Alessandro Padovani | Alberto Benussi | Maria Sofia Cotelli | Clarissa Ferrari | Valentina Cantoni | Valentina Dell’Era | Rosanna Turrone | Barbara Paghera | Barbara Borroni

Normalization of CSF pTau measurement by Aβ40 improves its performance as a biomarker of Alzheimer’s disease

JOURNAL ARTICLE published December 2020 in Alzheimer's Research & Therapy

Authors: Tengfei Guo | Deniz Korman | Renaud La Joie | Leslie M. Shaw | John Q. Trojanowski | William J. Jagust | Susan M. Landau | for the Alzheimer’s Disease Neuroimaging Initiative

Retraction Note: Increased Aβ42-α7-like nicotinic acetylcholine receptor complex level in lymphocytes is associated with apolipoprotein E4-driven Alzheimer’s disease pathogenesis

JOURNAL ARTICLE published December 2022 in Alzheimer's Research & Therapy

Authors: Hoau-Yan Wang | Caryn Trocmé-Thibierge | Andres Stucky | Sanket M. Shah | Jessica Kvasic | Amber Khan | Philippe Morain | Isabelle Guignot | Eva Bouguen | Karine Deschet | Maria Pueyo | Elisabeth Mocaer | Pierre-Jean Ousset | Bruno Vellas | Vera Kiyasova

First-In-Human safety and long-term exposure data for AAB-003 (PF-05236812) and biomarkers after intravenous infusions of escalating doses in patients with mild to moderate Alzheimer’s disease

JOURNAL ARTICLE published December 2016 in Alzheimer's Research & Therapy

Authors: Marielle Delnomdedieu | Sridhar Duvvuri | David Jianjun Li | Nazem Atassi | Ming Lu | H. Robert Brashear | Enchi Liu | Seth Ness | James W. Kupiec