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Loss of GPR3 reduces the amyloid plaque burden and improves memory in Alzheimer’s disease mouse models
Authors: Yunhong Huang | Aneta Skwarek-Maruszewska | Katrien Horré | Elke Vandewyer | Leen Wolfs | An Snellinx | Takashi Saito | Enrico Radaelli | Nikky Corthout | Julien Colombelli | Adrian C. Lo | Leen Van Aerschot | Zsuzsanna Callaerts-Vegh | Daniah Trabzuni | Koen Bossers | Joost Verhaagen | Mina Ryten | Sebastian Munck | Rudi D’Hooge | Dick F. Swaab | John Hardy | Takaomi C. Saido | Bart De Strooper | Amantha Thathiah
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Acute kidney injury promotes development of papillary renal cell adenoma and carcinoma from renal progenitor cells
Authors: Anna Julie Peired | Giulia Antonelli | Maria Lucia Angelotti | Marco Allinovi | Francesco Guzzi | Alessandro Sisti | Roberto Semeraro | Carolina Conte | Benedetta Mazzinghi | Sara Nardi | Maria Elena Melica | Letizia De Chiara | Elena Lazzeri | Laura Lasagni | Tiziano Lottini | Samuela Landini | Sabrina Giglio | Andrea Mari | Fabrizio Di Maida | Alessandro Antonelli | Francesco Porpiglia | Riccardo Schiavina | Vincenzo Ficarra | Davide Facchiano | Mauro Gacci | Sergio Serni | Marco Carini | George J. Netto | Rosa Maria Roperto | Alberto Magi | Christian Fynbo Christiansen | Mario Rotondi | Helen Liapis | Hans-Joachim Anders | Andrea Minervini | Maria Rosaria Raspollini | Paola Romagnani
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Lean body mass and the cardiovascular system constitute a female-specific relationship
Authors: Candela Diaz-Canestro | Brandon Pentz | Arshia Sehgal | Ranyao Yang | Aimin Xu | David Montero
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Transplantation of Genetically Corrected Human iPSC-Derived Progenitors in Mice with Limb-Girdle Muscular Dystrophy
Authors: Francesco Saverio Tedesco | Mattia F. M. Gerli | Laura Perani | Sara Benedetti | Federica Ungaro | Marco Cassano | Stefania Antonini | Enrico Tagliafico | Valentina Artusi | Emanuela Longa | Rossana Tonlorenzi | Martina Ragazzi | Giorgia Calderazzi | Hidetoshi Hoshiya | Ornella Cappellari | Marina Mora | Benedikt Schoser | Peter Schneiderat | Mitsuo Oshimura | Roberto Bottinelli | Maurilio Sampaolesi | Yvan Torrente | Vania Broccoli | Giulio Cossu
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Host-microbe multiomic profiling reveals age-dependent immune dysregulation associated with COVID-19 immunopathology
Authors: Hoang Van Phan | Alexandra Tsitsiklis | Cole P. Maguire | Elias K. Haddad | Patrice M. Becker | Seunghee Kim-Schulze | Brian Lee | Jing Chen | Annmarie Hoch | Harry Pickering | Patrick van Zalm | Matthew C. Altman | Alison D. Augustine | Carolyn S. Calfee | Steve Bosinger | Charles B. Cairns | Walter Eckalbar | Leying Guan | Naresh Doni Jayavelu | Steven H. Kleinstein | Florian Krammer | Holden T. Maecker | Al Ozonoff | Bjoern Peters | Nadine Rouphael | Ruth R. Montgomery | Elaine Reed | Joanna Schaenman | Hanno Steen | Ofer Levy | Joann Diray-Arce | Charles R. Langelier | David J. Erle | Carolyn M. Hendrickson | Kirsten N. Kangelaris | Viet Nguyen | Deanna Lee | Suzanna Chak | Rajani Ghale | Ana Gonzalez | Alejandra Jauregui | Carolyn Leroux | Luz Torres Altamirano | Ahmad Sadeed Rashid | Andrew Willmore | Prescott G. Woodruff | Matthew F. Krummel | Sidney Carrillo | Alyssa Ward | Ravi Patel | Michael Wilson | Ravi Dandekar | Bonny Alvarenga | Jayant Rajan | Andrew W. Schroeder | Gabriela K. Fragiadakis | Eran Mick | Yanedth Sanchez Guerrero | Christina Love | Lenka Maliskova | Michael Adkisson | Lauren I. R. Ehrlich | Esther Melamed | Justin F. Rousseau | Kerin C. Hurley | Janelle N. Geltman | Nadia Siles | Jacob E. Rogers | Michele A. Kutzler | Mariana Bernui | Gina Cusimano | Jennifer Connors | Kyra Woloszczuk | David Joyner | Carolyn Edwards | Edward Lin | Nataliya Melnyk | Debra L. Powell | James N. Kim | I. Michael Goonewardene | Brent Simmons | Cecilia M. Smith | Mark Martens | Brett Croen | Nicholas C. Semenza | Mathew R. Bell | Sara Furukawa | Renee McLin | George P. Tegos | Brandon Rogowski | Nathan Mege | Kristen Ulring | Steven M. Holland | Lindsey B. Rosen | Serena Lee | Tatyana Vaysman | Ana Fernandez-Sesma | Viviana Simon | Harm Van Bakel | Ana Silvia Gonzalez-Reiche | Jingjing Qi | Juan Manuel Carreño | Gagandeep Singh | Ariel Raskin | Johnstone Tcheou | Zain Khalil | Adriana van de Guchte | Keith Farrugia | Zenab Khan | Geoffrey Kelly | Komal Srivastava | Lily Eaker | Maria Carolina Bermúdez González | Lubbertus C. F. Mulder | Katherine Beach | Benoit Fatou | Kinga Smolen | Arthur Viode | Simon van Haren | Meenakshi Jha | Alvin Kho | Carly E. Milliren | Ana C. Chang | Kerry McEnaney | Brenda Barton | Claudia Lentucci | Maimouna Murphy | Mehmet Saluvan | Tanzia Shaheen | Shanshan Liu | Caitlin Syphurs | Marisa Albert | Arash Nemati Hayati | Robert Bryant | James Abraham | Ramin Salehi-Rad | Adreanne M. Rivera | Subha Sen | David Elashoff | Dawn C. Ward | Scott Presnell | Bernard Kohr | Azlann Arnett | Arun K. Boddapati | Greg K. Tharp | Kathryn L. Pellegrini | Brandi Johnson | Bernadine Panganiban | Christopher Huerta | Evan J. Anderson | Hady Samaha | Jonathan Sevransky | Laurel Bristow | Elizabeth Beagle | David Cowan | Sydney Hamilton | Thomas Hodder | Denise Esserman | Anderson Brito | Jessica Rothman | Nathan Grubaugh | Albert I. Ko | David A. Hafler | Albert C. Shaw | Jeremy Gygi | Shrikant Pawar | Anna Konstorum | Ernie Chen | Chris Cotsapas | Xiaomei Wang | Leqi Xu | Charles Dela Cruz | Akiko Iwasaki | Subhasis Mohanty | Allison Nelson | Yujiao Zhao | Shelli Farhadian | Hiromitsu Asashima | Bali Pulendran | R. Kari C. Nadeau | Yael Rosenberg-Hasson | Michael Leipold | Natalia Sigal | Angela Rogers | Andrea Fernandez | Monali Manohar | Evan Do | Iris Chang | Randi Vita | Kerstin Westendorf | David B. Corry | Farrah Kheradmand | Li-Zhen Song | Ebony Nelson | Lindsey R. Baden | Kevin Mendez | Jessica Lasky-Su | Alexandra Tong | Rebecca Rooks | Rafick-Pierre Sekaly | Slim Fourati | Grace A. McComsey | Paul Harris | Scott Sieg | Susan Pereira Ribeiro | James A. Overton | Adeeb Rahman | Scott R. Hutton | Greg Michelotti | Kari Wong | Vicki Seyfert-Margolis | Jordan P. Metcalf | Nelson I. Agudelo Higuita | Lauren Sinko | J. Leland Booth | William B. Messer | Catherine L. Hough | Sarah Siegel | Peter Sullivan | Zhengchun Lu | Monica Kraft | Chris Bime | Jarrod Mosier | Heidi Erickson | Ron Schunk | Hiroki Kimura | Michelle Conway | Mark A. Atkinson | Scott C. Brakenridge | Ricardo F. Ungaro | Brittany Roth Manning | Jordan Oberhaus | Faheem W. Guirgis | Brittany Borresen | Matthew L. Anderson | IMPACC Network
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Deep learning assists detection of esophageal cancer and precursor lesions in a prospective, randomized controlled study
Authors: Shao-wei Li | Li-hui Zhang | Yue Cai | Xian-bin Zhou | Xin-yu Fu | Ya-qi Song | Shi-wen Xu | Shen-ping Tang | Ren-quan Luo | Qin Huang | Ling-ling Yan | Sai-qin He | Yu Zhang | Jun Wang | Shu-qiong Ge | Bin-bin Gu | Jin-bang Peng | Yi Wang | Li-na Fang | Wei-dan Wu | Wen-guang Ye | Min Zhu | Ding-hai Luo | Xiu-xiu Jin | Hai-deng Yang | Jing-jing Zhou | Zhen-zhen Wang | Jian-fen Wu | Qiao-qiao Qin | Yan-di Lu | Fei Wang | Ya-hong Chen | Xia Chen | Shan-jing Xu | Tao-Hsin Tung | Chen-wen Luo | Li-ping Ye | Hong-gang Yu | Xin-li Mao
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Brain Maturation After Preterm Birth
Authors: Zoltán Molnár | Mary Rutherford
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Evidence for a protective role of placental growth factor in cardiovascular disease
Authors: Yihong Chen | Anna Hultgårdh Nilsson | Isabel Goncalves | Andreas Edsfeldt | Gunnar Engström | Olle Melander | Marju Orho-Melander | Uwe Rauch | Christoffer Tengryd | Shreenidhi M. Venuraju | Avijit Lahiri | Chun Liang | Jan Nilsson
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CD32 is expressed on cells with transcriptionally active HIV but does not enrich for HIV DNA in resting T cells
Authors: Mohamed Abdel-Mohsen | Leticia Kuri-Cervantes | Judith Grau-Exposito | Adam M. Spivak | Racheal A. Nell | Costin Tomescu | Surya Kumari Vadrevu | Leila B. Giron | Carla Serra-Peinado | Meritxell Genescà | Josep Castellví | Guoxin Wu | Perla M. Del Rio Estrada | Mauricio González-Navarro | Kenneth Lynn | Colin T. King | Sai Vemula | Kara Cox | Yanmin Wan | Qingsheng Li | Karam Mounzer | Jay Kostman | Ian Frank | Mirko Paiardini | Daria Hazuda | Gustavo Reyes-Terán | Douglas Richman | Bonnie Howell | Pablo Tebas | Javier Martinez-Picado | Vicente Planelles | Maria J. Buzon | Michael R. Betts | Luis J. Montaner
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Cystamine Suppresses Polyalanine Toxicity in a Mouse Model of Oculopharyngeal Muscular Dystrophy
Authors: Janet E. Davies | Claudia Rose | Sovan Sarkar | David C. Rubinsztein
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Disrupting mechanotransduction decreases fibrosis and contracture in split-thickness skin grafting
Authors: Kellen Chen | Dominic Henn | Michael Januszyk | Janos A. Barrera | Chikage Noishiki | Clark A. Bonham | Michelle Griffin | Ruth Tevlin | Theresa Carlomagno | Tara Shannon | Tobias Fehlmann | Artem A. Trotsyuk | Jagannath Padmanabhan | Dharshan Sivaraj | David P. Perrault | Alsu I. Zamaleeva | Chyna J. Mays | Autumn H. Greco | Sun Hyung Kwon | Melissa C. Leeolou | Savana L. Huskins | Sydney R. Steele | Katharina S. Fischer | Hudson C. Kussie | Smiti Mittal | Alana M. Mermin-Bunnell | Nestor M. Diaz Deleon | Christopher Lavin | Andreas Keller | Michael T. Longaker | Geoffrey C. Gurtner
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Targeting therapy-resistant prostate cancer via a direct inhibitor of the human heat shock transcription factor 1
Authors: Bushu Dong | Alex M. Jaeger | Philip F. Hughes | David R. Loiselle | J. Spencer Hauck | Yao Fu | Timothy A. Haystead | Jiaoti Huang | Dennis J. Thiele
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Arginine vasopressin receptor 1a is a therapeutic target for castration-resistant prostate cancer
Authors: Ning Zhao | Stephanie O. Peacock | Chen Hao Lo | Laine M. Heidman | Meghan A. Rice | Cale D. Fahrenholtz | Ann M. Greene | Fiorella Magani | Valeria A. Copello | Maria Julia Martinez | Yushan Zhang | Yehia Daaka | Conor C. Lynch | Kerry L. Burnstein
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Early skeletal outcomes after hematopoietic stem and progenitor cell gene therapy for Hurler syndrome
Authors: Giulia Consiglieri | Francesca Tucci | Maurizio De Pellegrin | Barbara Guerrini | Alessandro Cattoni | Giulia Risca | Stefano Scarparo | Marina Sarzana | Silvia Pontesilli | Renata Mellone | Serena Gasperini | Stefania Galimberti | Paolo Silvani | Chiara Filisetti | Silvia Darin | Giulia Forni | Simona Miglietta | Ludovica Santi | Marcella Facchini | Ambra Corti | Francesca Fumagalli | Maria Pia Cicalese | Valeria Calbi | Maddalena Migliavacca | Federica Barzaghi | Francesca Ferrua | Vera Gallo | Salvatore Recupero | Daniele Canarutto | Matteo Doglio | Lucia Tedesco | Nicola Volpi | Attilio Rovelli | Giancarlo la Marca | Maria Grazia Valsecchi | Stefano Zancan | Fabio Ciceri | Luigi Naldini | Cristina Baldoli | Rossella Parini | Bernhard Gentner | Alessandro Aiuti | Maria Ester Bernardo
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A multi-specific, multi-affinity antibody platform neutralizes sarbecoviruses and confers protection against SARS-CoV-2 in vivo
Authors: Clare Burn Aschner | Krithika Muthuraman | Iga Kucharska | Hong Cui | Katherine Prieto | Manoj S. Nair | Maple Wang | Yaoxing Huang | Natasha Christie-Holmes | Betty Poon | Jessica Lam | Azmiri Sultana | Robert Kozak | Samira Mubareka | John L. Rubinstein | Edurne Rujas | Bebhinn Treanor | David D. Ho | Arif Jetha | Jean-Philippe Julien
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A ticking time bomb hidden in plain sight
Authors: Sukanya Narasimhan | Durland Fish | Joao H. F. Pedra | Utpal Pal | Erol Fikrig
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Erratum for Research Article “Patient-derived glial enriched progenitors repair functional deficits due to white matter stroke and vascular dementia in rodents” by I. Llorente
et al
.
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USP2 inhibition prevents infection with ACE2-dependent coronaviruses in vitro and is protective against SARS-CoV-2 in mice
Authors: Fabin Dang | Lei Bai | Jiazhen Dong | Xiaoping Hu | Jingchao Wang | Joao A. Paulo | Yan Xiong | Xiaowei Liang | Yishuang Sun | Yuncai Chen | Ming Guo | Xin Wang | Zhixiang Huang | Hiroyuki Inuzuka | Li Chen | Chen Chu | Jianping Liu | Tao Zhang | Abdol-Hossein Rezaeian | Jing Liu | Husnu Ümit Kaniskan | Bo Zhong | Jinfang Zhang | Michael Letko | Jian Jin | Ke Lan | Wenyi Wei
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Erratum for the Research Article “Nuclear receptor PXR targets AKR1B7 to protect mitochondrial metabolism and renal function in AKI” by X. Yu
et al
.
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CNS therapeutics: Immune cells break the barriers
Authors: Karine Thai | Alexandre Prat
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