Liquid biopsy: Clues on prostate cancer drug resistance

JOURNAL ARTICLE published 4 November 2015 in Science Translational Medicine

Authors: Michael T. Schweizer | Emmanuel S. Antonarakis

Clinical trials for neurodevelopmental disorders: At a therapeutic frontier

JOURNAL ARTICLE published 13 January 2016 in Science Translational Medicine

Authors: Shafali S. Jeste | Daniel H. Geschwind

Bone morphogenetic protein 9 is a candidate prognostic biomarker and host-directed therapy target for sepsis

JOURNAL ARTICLE published 31 January 2024 in Science Translational Medicine

Authors: Haobo Bai | Qian Lu | Chunxiang Wu | Fang Xu | Jiayu Liu | Ke Wang | Hao Ding | Yibing Yin | Yi Liu | Xiaofei Lai | Ju Cao

Melanocortin-1 receptor activation is neuroprotective in mouse models of neuroinflammatory disease

JOURNAL ARTICLE published 26 October 2016 in Science Translational Medicine

Authors: Nadine Mykicki | Alexander M. Herrmann | Nicholas Schwab | René Deenen | Tim Sparwasser | Andreas Limmer | Lydia Wachsmuth | Luisa Klotz | Karl Köhrer | Cornelius Faber | Heinz Wiendl | Thomas A. Luger | Sven G. Meuth | Karin Loser

Translational impact of NIH-funded nonhuman primate research in transplantation

JOURNAL ARTICLE published 10 July 2019 in Science Translational Medicine

Research funded by National Heart, Lung, and Blood Institute (P01HL018646) | National Institute of Allergy and Infectious Diseases (P01AI123086) | National Institute of Allergy and Infectious Diseases (U01AI131470) | National Institute of Allergy and Infectious Diseases (U19 AI131471-01) | National Institute of Allergy and Infectious Diseases (U19 AI051731) | National Institute of Allergy and Infectious Diseases (U01 AI074635)

Authors: Stuart J. Knechtle | Julia M. Shaw | Bernhard J. Hering | Kristy Kraemer | Joren C. Madsen

RNA-Based Gene Therapy for HIV with Lentiviral Vector–Modified CD34 ⁺ Cells in Patients Undergoing Transplantation for AIDS-Related Lymphoma

JOURNAL ARTICLE published 16 June 2010 in Science Translational Medicine

Authors: David L. DiGiusto | Amrita Krishnan | Lijing Li | Haitang Li | Shirley Li | Anitha Rao | Shu Mi | Priscilla Yam | Sherri Stinson | Michael Kalos | Joseph Alvarnas | Simon F. Lacey | Jiing-Kuan Yee | Mingjie Li | Larry Couture | David Hsu | Stephen J. Forman | John J. Rossi | John A. Zaia

Senescence-associated secretory phenotype contributes to pathological angiogenesis in retinopathy

JOURNAL ARTICLE published 26 October 2016 in Science Translational Medicine

Authors: Malika Oubaha | Khalil Miloudi | Agnieszka Dejda | Vera Guber | Gaëlle Mawambo | Marie-Anne Germain | Guillaume Bourdel | Natalija Popovic | Flavio A. Rezende | Randal J. Kaufman | Frédérick A. Mallette | Przemyslaw Sapieha

Broadly neutralizing antibodies targeting the HIV-1 envelope V2 apex confer protection against a clade C SHIV challenge

JOURNAL ARTICLE published 6 September 2017 in Science Translational Medicine

Research funded by National Institute of Allergy and Infectious Diseases (award306473,AI106408) | National Institute of Allergy and Infectious Diseases (award306474,AI126603) | National Institute of Allergy and Infectious Diseases (award306475,AI100663) | National Institute of Allergy and Infectious Diseases (award306476,AI096040) | amfAR (award306477,109219)

Authors: Boris Julg | Lawrence J. Tartaglia | Brandon F. Keele | Kshitij Wagh | Amarendra Pegu | Devin Sok | Peter Abbink | Stephen D. Schmidt | Keyun Wang | Xuejun Chen | M. Gordon Joyce | Ivelin S. Georgiev | Misook Choe | Peter D. Kwong | Nicole A. Doria-Rose | Khoa Le | Mark K. Louder | Robert T. Bailer | Penny L. Moore | Bette Korber | Michael S. Seaman | Salim S. Abdool Karim | Lynn Morris | Richard A. Koup | John R. Mascola | Dennis R. Burton | Dan H. Barouch

Longitudinal Change in CSF Biomarkers in Autosomal-Dominant Alzheimer’s Disease

JOURNAL ARTICLE published 5 March 2014 in Science Translational Medicine

Authors: Anne M. Fagan | Chengjie Xiong | Mateusz S. Jasielec | Randall J. Bateman | Alison M. Goate | Tammie L. S. Benzinger | Bernardino Ghetti | Ralph N. Martins | Colin L. Masters | Richard Mayeux | John M. Ringman | Martin N. Rossor | Stephen Salloway | Peter R. Schofield | Reisa A. Sperling | Daniel Marcus | Nigel J. Cairns | Virginia D. Buckles | Jack H. Ladenson | John C. Morris | David M. Holtzman | The Dominantly Inherited Alzheimer Network

The Human Gut Microbiota and Undernutrition

JOURNAL ARTICLE published 6 June 2012 in Science Translational Medicine

Authors: Jeffrey I. Gordon | Kathryn G. Dewey | David A. Mills | Ruslan M. Medzhitov

The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer’s disease risk

JOURNAL ARTICLE published 14 August 2019 in Science Translational Medicine

Research funded by National Institutes of Health (R01AG044546) | National Institutes of Health (P01AG003991) | National Institutes of Health (RF1AG053303) | National Institutes of Health (R01AG058501) | National Institutes of Health (R01AG035083)

Authors: Yuetiva Deming | Fabia Filipello | Francesca Cignarella | Claudia Cantoni | Simon Hsu | Robert Mikesell | Zeran Li | Jorge L Del-Aguila | Umber Dube | Fabiana Geraldo Farias | Joseph Bradley | John Budde | Laura Ibanez | Maria Victoria Fernandez | Kaj Blennow | Henrik Zetterberg | Amanda Heslegrave | Per M Johansson | Johan Svensson | Bengt Nellgård | Alberto Lleo | Daniel Alcolea | Jordi Clarimon | Lorena Rami | José Luis Molinuevo | Marc Suárez-Calvet | Estrella Morenas-Rodríguez | Gernot Kleinberger | Michael Ewers | Oscar Harari | Christian Haass | Thomas J Brett | Bruno A. Benitez | Celeste M. Karch | Laura Piccio | Carlos Cruchaga

Evaluating strategies to improve rotavirus vaccine impact during the second year of life in Malawi

JOURNAL ARTICLE published 14 August 2019 in Science Translational Medicine

Research funded by National Institute of Allergy and Infectious Diseases (R01AI112970) | National Institute of Allergy and Infectious Diseases (R01AI112970) | Wellcome Trust (091909/Z/10/Z) | Wellcome Trust (102466/Z/13/A) | Wellcome Trust (201945/Z/16/Z)

Authors: Virginia E. Pitzer | Aisleen Bennett | Naor Bar-Zeev | Khuzwayo C. Jere | Benjamin A. Lopman | Joseph A. Lewnard | Umesh D. Parashar | Nigel A. Cunliffe

Bioengineering Dermo-Epidermal Skin Grafts with Blood and Lymphatic Capillaries

JOURNAL ARTICLE published 29 January 2014 in Science Translational Medicine

Authors: Daniela Marino | Joachim Luginbühl | Simonetta Scola | Martin Meuli | Ernst Reichmann

Reversal of synapse loss in Alzheimer mouse models by targeting mGluR5 to prevent synaptic tagging by C1Q

JOURNAL ARTICLE published June 2022 in Science Translational Medicine

Authors: Joshua Spurrier | LaShae Nicholson | Xiaotian T. Fang | Austin J. Stoner | Takuya Toyonaga | Daniel Holden | Timothy R. Siegert | William Laird | Mary Alice Allnutt | Marius Chiasseu | A. Harrison Brody | Hideyuki Takahashi | Sarah Helena Nies | Azucena Pérez-Cañamás | Pragalath Sadasivam | Supum Lee | Songye Li | Le Zhang | Yiyun H. Huang | Richard E. Carson | Zhengxin Cai | Stephen M. Strittmatter

A Tissue Engineering Solution for Segmental Defect Regeneration in Load-Bearing Long Bones

JOURNAL ARTICLE published 4 July 2012 in Science Translational Medicine

Authors: Johannes C. Reichert | Amaia Cipitria | Devakara R. Epari | Siamak Saifzadeh | Pushpanjali Krishnakanth | Arne Berner | Maria A. Woodruff | Hanna Schell | Manav Mehta | Michael A. Schuetz | Georg N. Duda | Dietmar W. Hutmacher

Control of cytokinesis by β-adrenergic receptors indicates an approach for regulating cardiomyocyte endowment

JOURNAL ARTICLE published 9 October 2019 in Science Translational Medicine

Authors: Honghai Liu | Cheng-Hai Zhang | Niyatie Ammanamanchi | Sangita Suresh | Christopher Lewarchik | Krithika Rao | Gerrida M. Uys | Lu Han | Maryline Abrial | Dean Yimlamai | Balakrishnan Ganapathy | Christelle Guillermier | Nathalie Chen | Mugdha Khaladkar | Jennifer Spaethling | James H. Eberwine | Junhyong Kim | Stuart Walsh | Sangita Choudhury | Kathryn Little | Kimberly Francis | Mahesh Sharma | Melita Viegas | Abha Bais | Dennis Kostka | Jun Ding | Ziv Bar-Joseph | Yijen Wu | Vijay Yechoor | Mousumi Moulik | Jennifer Johnson | Jacqueline Weinberg | Miguel Reyes-Múgica | Matthew L. Steinhauser | Bernhard Kühn

Vasopressin stimulates the proliferation and differentiation of red blood cell precursors and improves recovery from anemia

JOURNAL ARTICLE published 29 November 2017 in Science Translational Medicine

Research funded by NIH Office of the Director, NIDCR (award353709,N/A)

Authors: Balázs Mayer | Krisztián Németh | Miklós Krepuska | Vamsee D. Myneni | Dragan Maric | John F. Tisdale | Matthew M. Hsieh | Naoya Uchida | Heon-Jin Lee | Michael J. Nemeth | Kenn Holmbeck | Constance Tom Noguchi | Heather Rogers | Soumyadeep Dey | Arne Hansen | Jeffrey Hong | Ian Chow | Sharon Key | Ildikó Szalayova | Jerome Pagani | Károly Markó | Ian McClain-Caldwell | Lynn Vitale-Cross | W. Scott Young | Michael J. Brownstein | Éva Mezey

Developing predictive assays: The phenotypic screening “rule of 3”

JOURNAL ARTICLE published 24 June 2015 in Science Translational Medicine

Authors: Fabien Vincent | Paula Loria | Marko Pregel | Robert Stanton | Linda Kitching | Karl Nocka | Regis Doyonnas | Claire Steppan | Adam Gilbert | Thomas Schroeter | Marie-Claire Peakman

Semen enhances HIV infectivity and impairs the antiviral efficacy of microbicides

JOURNAL ARTICLE published 12 November 2014 in Science Translational Medicine

Authors: Onofrio Zirafi | Kyeong-Ae Kim | Nadia R. Roan | Silvia F. Kluge | Janis A. Müller | Shibo Jiang | Benjamin Mayer | Warner C. Greene | Frank Kirchhoff | Jan Münch

Chronic hypoxia–induced Cirbp hypermethylation attenuates hypothermic cardioprotection via down-regulation of ubiquinone biosynthesis

JOURNAL ARTICLE published 24 April 2019 in Science Translational Medicine

Research funded by National Science Fund for Distinguished Young Scholars (81525002) | CAMS Innovation Fund for Medical Sciences (2017-IZM-1-00) | Graduate Innovation Fund Project of Peking Union Medical College (2015-1002-02-21)

Authors: Yiwei Liu | Junyue Xing | Yongnan Li | Qipeng Luo | Zhanhao Su | Xiaoling Zhang | Hao Zhang