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Electron density is not spherical: the many applications of the transferable aspherical atom model

JOURNAL ARTICLE published 2022 in Computational and Structural Biotechnology Journal

Authors: Marta Kulik | Paulina M. Dominiak

MLSP: A bioinformatics tool for predicting molecular subtypes and prognosis in patients with breast cancer

JOURNAL ARTICLE published 2022 in Computational and Structural Biotechnology Journal

Research funded by National Natural Science Foundation of China (31671447,81903539)

Authors: Jie Zhu | Weikaixin Kong | Liting Huang | Shixin Wang | Suzhen Bi | Yin Wang | Peipei Shan | Sujie Zhu

ProxyBind: A compendium of binding sites for proximity-induced pharmacology

JOURNAL ARTICLE published 2022 in Computational and Structural Biotechnology Journal

Authors: Evianne Rovers | Lihua Liu | Matthieu Schapira

RNAME: A comprehensive database of RNA modification enzymes

JOURNAL ARTICLE published 2022 in Computational and Structural Biotechnology Journal

Research funded by National Natural Science Foundation of China (31771471) | Natural Science Foundation of Sichuan Province (2022NSFSC1770)

Authors: Fulei Nie | Qiang Tang | Ying Liu | Huaizhi Qin | Shilong Liu | Meng Wu | Pengmian Feng | Wei Chen

The NPR/Hal family of protein kinases in yeasts: biological role, phylogeny and regulation under environmental challenges

JOURNAL ARTICLE published 2022 in Computational and Structural Biotechnology Journal

Research funded by Fundação para a Ciência e a Tecnologia (2022.01501,LA/P/0140/2020,PD/BD/142944/2018) | Institute for Bioengineering and Biosciences (UIDB/04565/2020,UIDP/04565/2020)

Authors: Miguel Antunes | Isabel Sá-Correia

Mammalian RNA switches: Molecular rheostats in gene regulation, disease, and medicine

JOURNAL ARTICLE published 2019 in Computational and Structural Biotechnology Journal

Research funded by National Institutes of Health (R01 HL132899,R01HL147954) | American Heart Association (13SDG15970006)

Authors: Kadiam C. Venkata Subbaiah | Omar Hedaya | Jiangbin Wu | Feng Jiang | Peng Yao

A conserved Neurite Outgrowth and Guidance motif with biomimetic potential in neuronal Cell Adhesion Molecules

JOURNAL ARTICLE published 2021 in Computational and Structural Biotechnology Journal

Research funded by Università degli Studi di Padova (PRAT2015 CPDA151948)

Authors: Giorgia Scapin | Matteo Gasparotto | Daniele Peterle | Simone Tescari | Elena Porcellato | Alberto Piovesan | Irene Righetto | Laura Acquasaliente | Vincenzo De Filippis | Francesco Filippini

Mechanical and Systems Biology of Cancer

JOURNAL ARTICLE published 2018 in Computational and Structural Biotechnology Journal

Research funded by Stand Up to Cancer Campaign for Cancer Research UK (C37275/A20146)

Authors: Fabian Spill | Chris Bakal | Michael Mak

Exploring the patient-microbiome interaction patterns for pan-cancer

JOURNAL ARTICLE published 2022 in Computational and Structural Biotechnology Journal

Research funded by National Natural Science Foundation of China (81974469)

Authors: Lan Zhao | William C.S. Cho | Jun-Li Luo

Can we infer tumor presence of single cell transcriptomes and their tumor of origin from bulk transcriptomes by machine learning?

JOURNAL ARTICLE published 2022 in Computational and Structural Biotechnology Journal

Authors: Hua-Ping Liu | Dongwen Wang | Hung-Ming Lai

Prediction of CRISPR/Cas9 single guide RNA cleavage efficiency and specificity by attention-based convolutional neural networks

JOURNAL ARTICLE published 2021 in Computational and Structural Biotechnology Journal

Authors: Guishan Zhang | Tian Zeng | Zhiming Dai | Xianhua Dai

Methods for integration of transcriptomic data in genome-scale metabolic models

JOURNAL ARTICLE published August 2014 in Computational and Structural Biotechnology Journal

Authors: Min Kyung Kim | Desmond S. Lun

Circulating biomarkers to monitor cancer progression and treatment

JOURNAL ARTICLE published 2016 in Computational and Structural Biotechnology Journal

Authors: Suthee Rapisuwon | Eveline E. Vietsch | Anton Wellstein

Genus-specific pattern of intrinsically disordered central regions in the nucleocapsid protein of coronaviruses

JOURNAL ARTICLE published 2020 in Computational and Structural Biotechnology Journal

Authors: Sailen Barik

Zeta-carbonic anhydrases show CS2 hydrolase activity: A new metabolic carbon acquisition pathway in diatoms?

JOURNAL ARTICLE published 2021 in Computational and Structural Biotechnology Journal

Authors: Vincenzo Alterio | Emma Langella | Martina Buonanno | Davide Esposito | Alessio Nocentini | Emanuela Berrino | Silvia Bua | Maurizio Polentarutti | Claudiu T. Supuran | Simona Maria Monti | Giuseppina De Simone

PathExNET: A tool for extracting pathway expression networks from gene expression statistics

JOURNAL ARTICLE published 2021 in Computational and Structural Biotechnology Journal

Authors: George Minadakis | Alfonso Muñoz-Pomer Fuentes | George Tsouloupas | Irene Papatheodorou | George M. Spyrou

Discovery of a highly efficient TylF methyltransferase via random mutagenesis for improving tylosin production

JOURNAL ARTICLE published 2023 in Computational and Structural Biotechnology Journal

Authors: Jingyan Fan | Zhiming Yao | Chaoyue Yan | Meilin Hao | Jun Dai | Wenjin Zou | Minghui Ni | Tingting Li | Lu Li | Shuo Li | Jie Liu | Qi Huang | Rui Zhou

Predicting the effects of cultivation condition on gene regulation in Escherichia coli by using deep learning

JOURNAL ARTICLE published 2023 in Computational and Structural Biotechnology Journal

Research funded by National Research Foundation of Korea (2018M3A9F3079664,2022M3J5A1056072,2022M3J5A1056117)

Authors: Mun Su Kwon | Joshua Julio Adidjaja | Hyun Uk Kim

Critical evaluation of the use of artificial data for machine learning based de novo peptide identification

JOURNAL ARTICLE published 2023 in Computational and Structural Biotechnology Journal

Research funded by Irish Research Council for Science, Engineering and Technology (GOIPG/2019/1650)

Authors: Kevin McDonnell | Enda Howley | Florence Abram

TRIM56 coiled-coil domain structure provides insights into its E3 ligase functions

JOURNAL ARTICLE published 2023 in Computational and Structural Biotechnology Journal

Research funded by National Institute of Allergy and Infectious Diseases (R01 AI080779,R01 AI155488) | American Heart Association (20CDA35260116) | American Pain Society (DE-AC02–06CH11357)

Authors: Xiaohua Lou | Binbin Ma | Yuan Zhuang | Xiang Xiao | Laurie J. Minze | Junji Xing | Zhiqiang Zhang | Xian C. Li